Exosome-Liposome Hybrid Nanoparticles Deliver CRISPR/Cas9 System in MSCs

Exosomes: Fundamental Biology and Roles in Cardiovascular Physiology

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Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo

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Macrophage Exosomes Induce Placental Inflammatory Cytokines: A Novel Mode of Maternal-Placental Messaging

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Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia

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Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation

(2016) Defang Li et al.   Nature Communications

MSC Transplantation Improves Osteopenia via Epigenetic Regulation of Notch Signaling in Lupus

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Current and future delivery systems for engineered nucleases: ZFN, TALEN and RGEN

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Exosomes as drug delivery vehicles for Parkinson's disease therapy

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Exogenous DNA Loading into Extracellular Vesicles via Electroporation is Size-Dependent and Enables Limited Gene Delivery

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Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

(2015) Silvana Konermann et al.   NATURE

Gene therapy returns to centre stage

(2015) Luigi Naldini   NATURE

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

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CRISPR/Cas9-mediated genome engineering: An adeno-associated viral (AAV) vector toolbox

(2014) Elena Senís et al.   Biotechnology Journal

Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos

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Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

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CRISPR/Cas9 for genome editing: progress, implications and challenges

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Curcumin-primed exosomes mitigate endothelial cell dysfunction during hyperhomocysteinemia

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CRISPR-Cas systems for editing, regulating and targeting genomes

(2014) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

A guide to genome engineering with programmable nucleases

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Exosome Release and Low pH Belong to a Framework of Resistance of Human Melanoma Cells to Cisplatin

(2014) Cristina Federici et al.   PLoS One

The new frontier of genome engineering with CRISPR-Cas9

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Adenoviral vector delivery of RNA-guided CRISPR/Cas9 nuclease complexes induces targeted mutagenesis in a diverse array of human cells

(2014) Ignazio Maggio et al.   Scientific Reports

Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors

(2013) Su Chul Jang et al.   ACS Nano

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

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One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

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Extracellular vesicles: Exosomes, microvesicles, and friends

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Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

(2013) Seung Woo Cho et al.   NATURE BIOTECHNOLOGY

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

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Multiplex Genome Engineering Using CRISPR/Cas Systems

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A strategy of antigen incorporation into exosomes: Comparing cross-presentation levels of antigens delivered by engineered exosomes and by lentiviral virus-like particles

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Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

SiRNA delivery with exosome nanoparticles

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Microvesicle-mediated RNA Molecule Delivery System Using Monocytes/Macrophages

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