Matrine Ameliorates Colorectal Cancer in Rats via Inhibition of HMGB1 Signaling and Downregulation of IL-6, TNF-α, and HMGB1

The use of Chinese herbal medicine as an adjuvant therapy to reduce incidence of chronic hepatitis in colon cancer patients: A Taiwanese population-based cohort study

(2017) Tsai-Hui Lin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cytokine Imbalance as a Common Mechanism in Both Psoriasis and Rheumatoid Arthritis

(2017) Yong Tan et al.   MEDIATORS OF INFLAMMATION

Strong association of interleukin-6 −174G/C promoter single nucleotide polymorphism with a decreased risk of colorectal cancer in ethnic Kashmiri population: A case control study

(2017) Mujeeb Zafar Banday et al.   TUMOR BIOLOGY

Clinicopathological significance of overexpression of interleukin-6 in colorectal cancer

(2017) Jun Zeng et al.   WORLD JOURNAL OF GASTROENTEROLOGY

KRAS and TP53 mutations in inflammatory bowel disease-associated colorectal cancer: a meta-analysis

(2017) Lijun Du et al.   Oncotarget

Therapeutic efficacy of Traditional Chinese medicine, “Kuan-Sin-Yin”, in patients undergoing chemotherapy for advanced colon cancer – A controlled trial

(2016) Tsai-Ju Chien et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Polypharmacology in Drug Discovery: A Review from Systems Pharmacology Perspective

(2016) Wenjuan Zhang et al.   CURRENT PHARMACEUTICAL DESIGN

Association between TNF-α-308G>A and -238G>A gene polymorphisms and TNF-α serum levels in Mexican colorectal cancer patients

(2016) I.A. Gutiérrez-Hurtado et al.   GENETICS AND MOLECULAR RESEARCH

Network meta-analysis of Chinese herb injections combined with FOLFOX chemotherapy in the treatment of advanced colorectal cancer

(2016) L. Ge et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Nuclear Export of Ubiquitinated Proteins Determines the Sensitivity of Colorectal Cancer to Proteasome Inhibitor

(2016) Tingyu Wu et al.   MOLECULAR CANCER THERAPEUTICS

Increased transforming growth factor β and interleukin 10 transcripts in peripheral blood mononuclear cells of colorectal cancer patients

(2016) Noyko S. Stanilov et al.   Wspolczesna Onkologia-Contemporary Oncology

Interleukin-6 promotes tumor progression in colitis-associated colorectal cancer through HIF-1α regulation

(2016) Jun Han et al.   Oncology Letters

Matrine derivative YF-18 inhibits lung cancer cell proliferation and migration through down-regulating Skp2

(2016) Lichuan Wu et al.   Oncotarget

TGF-β1 promotes colorectal cancer immune escape by elevating B7-H3 and B7-H4 via the miR-155/miR-143 axis

(2016) Xinru Zhou et al.   Oncotarget

Molecular network-based analysis of Guizhi-Shaoyao-Zhimu decoction, a TCM herbal formula, for treatment of diabetic peripheral neuropathy

(2015) Ning Zhao et al.   ACTA PHARMACOLOGICA SINICA

Mechanisms and Αpplications of Ιnterleukins in Cancer Immunotherapy

(2015) Doxakis Anestakis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TP53 loss creates therapeutic vulnerability in colorectal cancer

(2015) Yunhua Liu et al.   NATURE

Role of TGF-β1 in Human Colorectal Cancer and Effects after Cantharidinate Intervention

(2014) Jie Ma et al.   Asian Pacific Journal of Cancer Prevention

Prescription patterns of Chinese herbal products for post-surgery colon cancer patients in Taiwan

(2014) Te-Hsin Chao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Uncovering the role of p53 splice variants in human malignancy: a clinical perspective

(2013) Jean-Christophe Bourdon et al.   OncoTargets and Therapy

The Emerging Paradigm of Network Medicine in the Study of Human Disease

(2012) Stephen Y. Chan et al.   CIRCULATION RESEARCH

Traditional Chinese Medicine-Based Network Pharmacology Could Lead to New Multicompound Drug Discovery

(2012) Jian Li et al.   Evidence-based Complementary and Alternative Medicine

Tumor Microenvironment Macrophage Inhibitory Factor Directs the Accumulation of Interleukin-17-producing Tumor-infiltrating Lymphocytes and Predicts Favorable Survival in Nasopharyngeal Carcinoma Patients

(2012) Jiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

Non-histone nuclear factor HMGB1 as a therapeutic target in colorectal cancer

(2011) Hitoshi Ohmori et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Colorectal cancer

(2010) David Cunningham et al.   LANCET

Network-Based Relating Pharmacological and Genomic Spaces for Drug Target Identification

(2010) Shiwen Zhao et al.   PLoS One

A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

(2010) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting HMGB1 in inflammation

(2009) Huan Yang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Unknown

(2008) John Klune et al.   MOLECULAR MEDICINE