miR-21 Protects Against Ischemia/Reperfusion-Induced Acute Kidney Injury by Preventing Epithelial Cell Apoptosis and Inhibiting Dendritic Cell Maturation

The feedback loop between miR-21, PDCD4 and AP-1 functions as a driving force for renal fibrogenesis

(2018) Qi Sun et al.   JOURNAL OF CELL SCIENCE

MicroRNAs associated with the development of kidney diseases in humans and animals

(2018) Osamu Ichii et al.   Journal of Toxicologic Pathology

Role of miR-21 on vascular endothelial cells in the protective effect of renal delayed ischemic preconditioning

(2017) Xialian Xu et al.   Molecular Medicine Reports

miR-21 contributes to renal protection by targeting prolyl hydroxylase domain protein 2 in delayed ischaemic preconditioning

(2017) Xiaoyan Jiao et al.   NEPHROLOGY

Renal Protection Mediated by Hypoxia Inducible Factor-1α Depends on Proangiogenesis Function of miR-21 by Targeting Thrombospondin 1

(2017) Xialian Xu et al.   TRANSPLANTATION

Urinary miR-21 as a potential biomarker of hypertensive kidney injury and fibrosis

(2017) Congcong Chen et al.   Scientific Reports

Upregulation of miR-21 by Ghrelin Ameliorates Ischemia/Reperfusion-Induced Acute Kidney Injury by Inhibiting Inflammation and Cell Apoptosis

(2016) Wanzhe Zhang et al.   DNA AND CELL BIOLOGY

TGF-β1/Smads and miR-21 in Renal Fibrosis and Inflammation

(2016) Agnieszka Loboda et al.   MEDIATORS OF INFLAMMATION

Plasma microRNA-21 for the early prediction of acute kidney injury in patients undergoing major cardiac surgery

(2016) Luise Gaede et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Vhl deletion in renal epithelia causes HIF-1α-dependent, HIF-2α-independent angiogenesis and constitutive diuresis

(2016) Désirée Schönenberger et al.   Oncotarget

miR-146a is essential for lipopolysaccharide (LPS)-induced cross-tolerance against kidney ischemia/reperfusion injury in mice

(2016) Yan Dai et al.   Scientific Reports

Acid-sensing ion channels are expressed in the ventrolateral medulla and contribute to central chemoreception

(2016) Nana Song et al.   Scientific Reports

miR-21-5p renal expression is associated with fibrosis and renal survival in patients with IgA nephropathy

(2016) Marie-Flore Hennino et al.   Scientific Reports

Adaptive response to hypoxia and remote ischaemia pre-conditioning: a new hypoxia-inducible factors era in clinical medicine

(2015) S. N. Heyman et al.   Acta Physiologica

Xenon Protects Against Septic Acute Kidney Injury via miR-21 Target Signaling Pathway*

(2015) Ping Jia et al.   CRITICAL CARE MEDICINE

Ultrasound-targeted microbubble destruction-mediated microRNA-21 transfection regulated PDCD4/NF-κB/TNF-α pathway to prevent coronary microembolization-induced cardiac dysfunction

(2015) Q Su et al.   GENE THERAPY

NFAT-1, Sp-1, Sp-3, and miR-21: New regulators of chemokine C receptor 7 expression in mature human dendritic cells

(2015) Carine Al Akoum et al.   HUMAN IMMUNOLOGY

Natural IgM Switches the Function of Lipopolysaccharide-Activated Murine Bone Marrow-Derived Dendritic Cells to a Regulatory Dendritic Cell That Suppresses Innate Inflammation

(2015) P. I. Lobo et al.   JOURNAL OF IMMUNOLOGY

Betalactam antibiotics affect human dendritic cells maturation through MAPK/NF-kB systems. Role in allergic reactions to drugs

(2015) Soledad Lopez et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A novel cyclic helix B peptide inhibits dendritic cell maturation during amelioration of acute kidney graft rejection through Jak-2/STAT3/SOCS1

(2015) C Yang et al.   Cell Death & Disease

Vagotomy attenuates bleomycin-induced pulmonary fibrosis in mice

(2015) Nana Song et al.   Scientific Reports

Turning 21: Induction of miR-21 as a Key Switch in the Inflammatory Response

(2015) Frederick J. Sheedy   Frontiers in Immunology

A feedback regulatory loop between HIF-1α and miR-21 in response to hypoxia in cardiomyocytes

(2014) Yang Liu et al.   FEBS LETTERS

miR-21 in ischemia/reperfusion injury: a double-edged sword?

(2014) Xialian Xu et al.   PHYSIOLOGICAL GENOMICS

CD31 is a key coinhibitory receptor in the development of immunogenic dendritic cells

(2014) M. Clement et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-21 Contributes to Xenon-conferred Amelioration of Renal Ischemia–Reperfusion Injury in Mice

(2013) Ping Jia et al.   ANESTHESIOLOGY

Exclusive CX3CR1 dependence of kidney DCs impacts glomerulonephritis progression

(2013) Katharina Hochheiser et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor Necrosis Factor Alpha Promoter Polymorphism and Severity of Acute Kidney Injury

(2013) Paweena Susantitaphong et al.   NEPHRON CLINICAL PRACTICE

MicroRNA-21 in the pathogenesis of acute kidney injury

(2013) Ya-Feng Li et al.   Protein & Cell

Dendritic cells tolerized with adenosine A2AR agonist attenuate acute kidney injury

(2012) Li Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Dendritic Cell Sphingosine 1-Phosphate Receptor-3 Regulates Th1-Th2 Polarity in Kidney Ischemia-Reperfusion Injury

(2012) A. Bajwa et al.   JOURNAL OF IMMUNOLOGY

Delayed ischemic preconditioning contributes to renal protection by upregulation of miR-21

(2012) Xialian Xu et al.   KIDNEY INTERNATIONAL

Hypoxia Inducible Factor 1-Alpha (HIF-1 Alpha) Is Induced during Reperfusion after Renal Ischemia and Is Critical for Proximal Tubule Cell Survival

(2012) Elisa Conde et al.   PLoS One

Acid Sensing Ion Channel 1 in Lateral Hypothalamus Contributes to Breathing Control

(2012) Nana Song et al.   PLoS One

MicroRNA-21 Promotes Fibrosis of the Kidney by Silencing Metabolic Pathways

(2012) B. N. Chau et al.   Science Translational Medicine

CCR2 Plays a Critical Role in Dendritic Cell Maturation: Possible Role of CCL2 and NF- B

(2010) F. Jimenez et al.   JOURNAL OF IMMUNOLOGY

Identification of a microRNA signature of renal ischemia reperfusion injury

(2010) J. G. Godwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophages, Dendritic Cells, and Kidney Ischemia-Reperfusion Injury

(2010) Li Li et al.   SEMINARS IN NEPHROLOGY

Renal Dendritic Cells Ameliorate Nephrotoxic Acute Kidney Injury

(2009) R. K. Tadagavadi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Critical involvement of Th1-related cytokines in renal injuries induced by ischemia and reperfusion

(2008) Vanessa Nunes de Paiva et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inhibition of Hypoxia Inducible Factor Hydroxylases Protects Against Renal Ischemia-Reperfusion Injury

(2008) P. Hill et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY