Pharmacological Inhibition of Indoleamine 2,3-Dioxygenase-2 and Kynurenine 3-Monooxygenase, Enzymes of the Kynurenine Pathway, Significantly Diminishes Neuropathic Pain in a Rat Model

Targeting the Microglial Signaling Pathways: New Insights in the Modulation of Neuropathic Pain

(2016) Katarzyna Popiolek-Barczyk et al.   CURRENT MEDICINAL CHEMISTRY

Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model

(2016) Ewelina Rojewska et al.   NEUROPHARMACOLOGY

Effects of indoleamine 2,3-dioxygenase inhibitor in non-Hodgkin lymphoma model mice

(2015) Nobuhiko Nakamura et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Expression of the Kynurenine Pathway in Human Peripheral Blood Mononuclear Cells: Implications for Inflammatory and Neurodegenerative Disease

(2015) Simon P. Jones et al.   PLoS One

1-Methyl-D-Tryptophan Potentiates TGF-β-Induced Epithelial-Mesenchymal Transition in T24 Human Bladder Cancer Cells

(2015) Rodrigo Barbosa Oliveira Brito et al.   PLoS One

PD98059 Influences Immune Factors and Enhances Opioid Analgesia in Model of Neuropathy

(2015) Ewelina Rojewska et al.   PLoS One

Involvement of pro- and antinociceptive factors in minocycline analgesia in rat neuropathic pain model

(2014) Ewelina Rojewska et al.   JOURNAL OF NEUROIMMUNOLOGY

Expression Profiling of Genes Modulated by Minocycline in a Rat Model of Neuropathic Pain

(2014) Ewelina Rojewska et al.   Molecular Pain

Minocycline prevents dynorphin-induced neurotoxicity during neuropathic pain in rats

(2014) Ewelina Rojewska et al.   NEUROPHARMACOLOGY

Indoleamine 2,3-Dioxygenase (IDO) Activity During the Primary Immune Response to Influenza Infection Modifies the Memory T Cell Response to Influenza Challenge

(2014) Leo K. Sage et al.   VIRAL IMMUNOLOGY

Kynurenines in CNS disease: regulation by inflammatory cytokines

(2014) Brian M. Campbell et al.   Frontiers in Neuroscience

Structural basis of kynurenine 3-monooxygenase inhibition

(2013) Marta Amaral et al.   NATURE

Effects of selective and non-selective inhibitors of nitric oxide synthase on morphine- and endomorphin-1-induced analgesia in acute and neuropathic pain in rats

(2013) Wioletta Makuch et al.   NEUROPHARMACOLOGY

Quinolinic Acid: An Endogenous Neurotoxin with Multiple Targets

(2013) Rafael Lugo-Huitrón et al.   Oxidative Medicine and Cellular Longevity

Bacterial expression of human kynurenine 3-monooxygenase: Solubility, activity, purification

(2013) K. Wilson et al.   PROTEIN EXPRESSION AND PURIFICATION

Kynurenines and other novel therapeutic strategies in the treatment of dementia

(2013) Zsófia Majláth et al.   Therapeutic Advances in Neurological Disorders

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

(2011) Daniel Zwilling et al.   CELL

Kynurenine Metabolites and Migraine: Experimental Studies and Therapeutic Perspectives

(2011) Annamaria Fejes et al.   Current Neuropharmacology

Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats

(2011) Nady Braidy et al.   FEBS Journal

The Indoleamine-2,3-Dioxygenase (IDO) Inhibitor 1-Methyl-D-tryptophan Upregulates IDO1 in Human Cancer Cells

(2011) Christiane A. Opitz et al.   PLoS One

Peripheral and cerebral metabolic abnormalities of the tryptophan–kynurenine pathway in a murine model of major depression

(2010) Anthony Laugeray et al.   BEHAVIOURAL BRAIN RESEARCH

Differential activation of spinal microglial and astroglial cells in a mouse model of peripheral neuropathic pain

(2009) Joanna Mika et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

On the relationship between the two branches of the kynurenine pathway in the rat brainin vivo

(2009) Laura Amori et al.   JOURNAL OF NEUROCHEMISTRY

Minocycline reduces the injury-induced expression of prodynorphin and pronociceptin in the dorsal root ganglion in a rat model of neuropathic pain

(2009) J. Mika et al.   NEUROSCIENCE

RuBi-Glutamate: Two-photon and visible-light photoactivation of neurons and dendritic spines

(2009) Elodie Fino   Frontiers in Neural Circuits

Indoleamine 2,3-dioxygenase in infection: the paradox of an evasive strategy that benefits the host

(2008) T ZELANTE et al.   MICROBES AND INFECTION

Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys

(2007) L GREGOIRE et al.   BEHAVIOURAL BRAIN RESEARCH