Inhibition of Glucose-6-Phosphate Dehydrogenase Reverses Cisplatin Resistance in Lung Cancer Cells via the Redox System

Disrupting G6PD-mediated Redox homeostasis enhances chemosensitivity in colorectal cancer

(2017) H-Q Ju et al.   ONCOGENE

Overexpression of G6PD Represents a Potential Prognostic Factor in Clear Cell Renal Cell Carcinoma

(2017) Qiao Zhang et al.   Journal of Cancer

Nrf2 inhibition reverses the resistance of cisplatin-resistant head and neck cancer cells to artesunate-induced ferroptosis

(2017) Jong-Lyel Roh et al.   Redox Biology

Emerging Role of the Pentose Phosphate Pathway in Hepatocellular Carcinoma

(2017) Marta Anna Kowalik et al.   Frontiers in Oncology

Effects of G6PD activity inhibition on the viability, ROS generation and mechanical properties of cervical cancer cells

(2016) Zishui Fang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Emerging role of NRF2 in chemoresistance by regulating drug-metabolizing enzymes and efflux transporters

(2016) Xupeng Bai et al.   DRUG METABOLISM REVIEWS

Cisplatin resistance and opportunities for precision medicine

(2016) Lauren Amable   PHARMACOLOGICAL RESEARCH

Nrf2 inhibition sensitizes cholangiocarcinoma cells to cytotoxic and antiproliferative activities of chemotherapeutic agents

(2016) Papavee Samatiwat et al.   TUMOR BIOLOGY

Cancer drug resistance: redox resetting renders a way

(2016) Yuan Liu et al.   Oncotarget

Cryptotanshinone Reverses Cisplatin Resistance of Human Lung Carcinoma A549 Cells through Down-Regulating Nrf2 Pathway

(2015) Chen Xia et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling

(2015) Ruiting Lin et al.   NATURE CELL BIOLOGY

G6PD downregulation triggered growth inhibition and induced apoptosis by regulating STAT3 signaling pathway in esophageal squamous cell carcinoma

(2015) Xin Wang et al.   TUMOR BIOLOGY

Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death

(2015) Daniela Catanzaro et al.   Oncotarget

Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma

(2015) Giuseppe Lucarelli et al.   Oncotarget

The pentose phosphate pathway and cancer

(2014) Krushna C. Patra et al.   TRENDS IN BIOCHEMICAL SCIENCES

Regulation of the pentose phosphate pathway in cancer

(2014) Peng Jiang et al.   Protein & Cell

Molecular Pathways: Reactive Oxygen Species Homeostasis in Cancer Cells and Implications for Cancer Therapy

(2013) V. Nogueira et al.   CLINICAL CANCER RESEARCH

Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis

(2013) Anju Singh et al.   JOURNAL OF CLINICAL INVESTIGATION

Modulation of oxidative stress as an anticancer strategy

(2013) Chiara Gorrini et al.   NATURE REVIEWS DRUG DISCOVERY

Role of Glutathione in Cancer Progression and Chemoresistance

(2013) Nicola Traverso et al.   Oxidative Medicine and Cellular Longevity

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

Oxidative stress and cancer: An overview

(2012) Venus Sosa et al.   AGEING RESEARCH REVIEWS

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

(2012) Haoqiang Ying et al.   CELL

Adjuvant chemotherapy for resectable non-small-cell lung cancer: where is it going?

(2010) T. Le Chevalier   ANNALS OF ONCOLOGY