G6PD downregulation triggered growth inhibition and induced apoptosis by regulating STAT3 signaling pathway in esophageal squamous cell carcinoma

STAT3 the oncogene - still eluding therapy?

(2015) Matthew S. Wake et al.   FEBS Journal

Metabolic pathways promoting cancer cell survival and growth

(2015) Lindsey K. Boroughs et al.   NATURE CELL BIOLOGY

Changes in glucose-6-phosphate dehydrogenase expression results in altered behavior of HBV-associated liver cancer cells

(2014) Huaidong Hu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Glucose-6-phosphate Dehydrogenase: a Biomarker and Potential Therapeutic Target for Cancer

(2014) Chunhua Zhang et al.   Anti-Cancer Agents in Medicinal Chemistry

The pentose phosphate pathway and cancer

(2014) Krushna C. Patra et al.   TRENDS IN BIOCHEMICAL SCIENCES

High expression of astrocyte elevated gene-1 is associated with clinical staging, metastasis, and unfavorable prognosis in gastric carcinoma

(2014) Liangpeng Dong et al.   TUMOR BIOLOGY

Regulation of the pentose phosphate pathway in cancer

(2014) Peng Jiang et al.   Protein & Cell

Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model

(2013) Tao Hu et al.   BMC CANCER

A critical role of glucose-6-phosphate dehydrogenase in TAp73-mediated cell proliferation

(2013) Peng Jiang et al.   CELL CYCLE

PTEN antagonises Tcl1/hnRNPK-mediated G6PD pre-mRNA splicing which contributes to hepatocarcinogenesis

(2013) Xuehui Hong et al.   GUT

TAp73 enhances the pentose phosphate pathway and supports cell proliferation

(2013) Wenjing Du et al.   NATURE CELL BIOLOGY

Target protein for Xklp2 (TPX2), a microtubule-related protein, contributes to malignant phenotype in bladder carcinoma

(2013) Liang Yan et al.   TUMOR BIOLOGY

Increased PrLZ-mediated androgen receptor transactivation promotes prostate cancer growth at castration-resistant stage

(2012) Lei Li et al.   CARCINOGENESIS

Clinical Implication of Elevated Human Cervical Cancer Oncogene-1 Expression in Esophageal Squamous Cell Carcinoma

(2012) Ying Liu et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Expression of Id proteins is regulated by the Bcl-3 proto-oncogene in prostate cancer

(2012) K Ahlqvist et al.   ONCOGENE

PrLZ Protects Prostate Cancer Cells from Apoptosis Induced by Androgen Deprivation via the Activation of Stat3/Bcl-2 Pathway

(2011) D. Zhang et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Targeting cancer metabolism – aiming at a tumour's sweet-spot

(2011) Neil P. Jones et al.   DRUG DISCOVERY TODAY

Overexpression of G6PD is associated with poor clinical outcome in gastric cancer

(2011) Jixu Wang et al.   TUMOR BIOLOGY

Functional and biological analysis of Bcl-xL expression in human osteosarcoma

(2010) Zhao-Xia Wang et al.   BONE

Impaired dephosphorylation renders G6PD-knockdown HepG2 cells more susceptible to H2O2-induced apoptosis

(2010) Chang-Jun Lin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

(2010) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

Anti-Tumoral Effect of a Celecoxib Low Dose on a Model of Human Medullary Thyroid Cancer in Nude Mice

(2009) Virginie Quidville et al.   THYROID