Hydrogen Sulfide Reverses Aging-Associated Amygdalar Synaptic Plasticity and Fear Memory Deficits in Rats

Gasotransmitter hydrogen sulfide signaling in neuronal health and disease

(2018) Bindu D. Paul et al.   BIOCHEMICAL PHARMACOLOGY

Activation of TrkB by 7,8-Dihydroxyflavone Prevents Fear Memory Defects and Facilitates Amygdalar Synaptic Plasticity in Aging

(2018) Yan Zeng et al.   JOURNAL OF ALZHEIMERS DISEASE

Effects of ibuprofen on cognition and NMDA receptor subunit expression across aging

(2017) Alejandra Márquez Loza et al.   NEUROSCIENCE

Cystathionine-β-synthase-derived hydrogen sulfide is required for amygdalar long-term potentiation and cued fear memory in rats

(2017) Hai-Bo Chen et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

GluN2B-containing NMDA receptors contribute to the beneficial effects of hydrogen sulfide on cognitive and synaptic plasticity deficits in APP/PS1 transgenic mice

(2016) Yuan-Jian Yang et al.   NEUROSCIENCE

Modes of Physiologic H2S Signaling in the Brain and Peripheral Tissues

(2015) Bindu D. Paul et al.   ANTIOXIDANTS & REDOX SIGNALING

Forebrain NR2B overexpression enhancing fear acquisition and long-term potentiation in the lateral amygdala

(2015) Yanhong Duan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

NMDA Receptor Function During Senescence: Implication on Cognitive Performance

(2015) Ashok Kumar   Frontiers in Neuroscience

Aggravation of Seizure-like Events by Hydrogen Sulfide: Involvement of Multiple Targets that Control Neuronal Excitability

(2014) Yi Luo et al.   CNS Neuroscience & Therapeutics

Targeting the NMDA receptor subunit NR2B for treating or preventing age-related memory decline

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Regulation of emotional memory by hydrogen sulfide: role of GluN2B-containing NMDA receptor in the amygdala

(2014) Can-Ming Wang et al.   JOURNAL OF NEUROCHEMISTRY

Hydrogen sulfide improves spatial memory impairment and decreases production of Aβ in APP/PS1 transgenic mice

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Extrasynaptic NMDA Receptor in Excitotoxicity

(2014) Xianju Zhou et al.   NEUROSCIENTIST

Linking Redox Regulation of NMDAR Synaptic Function to Cognitive Decline during Aging

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Hydrogen sulfide slows down progression of experimental Alzheimer’s disease by targeting multiple pathophysiological mechanisms

(2013) Daniela Giuliani et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Reversal of age-related oxidative stress prevents hippocampal synaptic plasticity deficits by protecting d-serine-dependent NMDA receptor activation

(2012) Coline Haxaire et al.   AGING CELL

Memory in aged mice is rescued by enhanced expression of the GluN2B subunit of the NMDA receptor

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Dissecting the age-related decline on spatial learning and memory tasks in rodent models: N-methyl-D-aspartate receptors and voltage-dependent Ca2+ channels in senescent synaptic plasticity

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Changes in expression of splice cassettes of NMDA receptor GluN1 subunits within the frontal lobe and memory in mice during aging

(2011) Siba R. Das et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of Elevation of Brain Magnesium on Fear Conditioning, Fear Extinction, and Synaptic Plasticity in the Infralimbic Prefrontal Cortex and Lateral Amygdala

(2011) N. Abumaria et al.   JOURNAL OF NEUROSCIENCE

Aging redistributes medial prefrontal neuronal excitability and impedes extinction of trace fear conditioning

(2011) Catherine C. Kaczorowski et al.   NEUROBIOLOGY OF AGING

Protective Effects of Exogenous Hydrogen Sulfide on Neurons of Hippocampus in a Rat Model of Brain Ischemia

(2011) Zhanyong Li et al.   NEUROCHEMICAL RESEARCH

Glutathione Restores the Mechanism of Synaptic Plasticity in Aged Mice to That of the Adult

(2011) Julie M. Robillard et al.   PLoS One

Reversal of aging-associated hippocampal synaptic plasticity deficits by reductants via regulation of thiol redox and NMDA receptor function

(2010) Yuan-Jian Yang et al.   AGING CELL

Hydrogen Sulfide: Neurophysiology and Neuropathology

(2010) Li-Fang Hu et al.   ANTIOXIDANTS & REDOX SIGNALING

Neural mechanisms of ageing and cognitive decline

(2010) Nicholas A. Bishop et al.   NATURE

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

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Enhancement of Learning and Memory by Elevating Brain Magnesium

(2010) Inna Slutsky et al.   NEURON

Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of adult mice

(2009) T. Muller et al.   LEARNING & MEMORY

The effects of aging on N-methyl-d-aspartate receptor subunits in the synaptic membrane and relationships to long-term spatial memory

(2009) X. Zhao et al.   NEUROSCIENCE

Upregulation of Calcium/Calmodulin-Dependent Protein Kinase IV Improves Memory Formation and Rescues Memory Loss with Aging

(2008) H. Fukushima et al.   JOURNAL OF NEUROSCIENCE

Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long-term potentiation in the adult mouse CNS

(2008) Hideki Miwa et al.   JOURNAL OF PHYSIOLOGY-LONDON

Glutamate receptor subunits expression in memory-associated brain structures: Regional variations and effects of aging

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