Lipin-1 determines lung cancer cell survival and chemotherapy sensitivity by regulation of endoplasmic reticulum homeostasis and autophagy

Lipin-1 regulation of phospholipid synthesis maintains endoplasmic reticulum homeostasis and is critical for triple-negative breast cancer cell survival

(2017) Jingquan He et al.   FASEB JOURNAL

Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment

(2015) Laura Brohée et al.   Oncotarget

Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

(2014) Tomoyuki Mashimo et al.   CELL

Lipin-1 Regulates Autophagy Clearance and Intersects with Statin Drug Effects in Skeletal Muscle

(2014) Peixiang Zhang et al.   Cell Metabolism

The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

(2014) David Heras-Sandoval et al.   CELLULAR SIGNALLING

Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer

(2013) Balázs Győrffy et al.   PLoS One

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

(2013) X Sui et al.   Cell Death & Disease

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Induction of Autophagy by Palmitic Acid via Protein Kinase C-mediated Signaling Pathway Independent of mTOR (Mammalian Target of Rapamycin)

(2012) Shi Hao Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

(2011) Timothy R. Peterson et al.   CELL

Dual function lipin proteins and glycerolipid metabolism

(2011) Thurl E. Harris et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Lipins: Multifunctional Lipid Metabolism Proteins

(2010) Lauren S. Csaki et al.   Annual Review of Nutrition

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

A Diacylglycerol-Dependent Signaling Pathway Contributes to Regulation of Antibacterial Autophagy

(2010) Shahab Shahnazari et al.   Cell Host & Microbe

mTOR regulation of autophagy

(2010) Chang Hwa Jung et al.   FEBS LETTERS

LPIN1 gene mutations: a major cause of severe rhabdomyolysis in early childhood

(2010) Caroline Michot et al.   HUMAN MUTATION

Direct evidence for the up-regulation of Vps34 regulated by PKCγ during short-term treatment with morphine

(2009) Masahiro Shibasaki et al.   SYNAPSE

Thematic Review Series: Glycerolipids.Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism

(2008) Karen Reue et al.   JOURNAL OF LIPID RESEARCH

Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival

(2007) Christopher Fung et al.   MOLECULAR BIOLOGY OF THE CELL