The current state and future perspectives of cannabinoids in cancer biology

Cannabidiol Reduces Leukemic Cell Size – But Is It Important?

(2017) Nikoletta Kalenderoglou et al.   Frontiers in Pharmacology

Cannabinoid pharmacology in cancer research: A new hope for cancer patients?

(2016) Farideh A. Javid et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The use of cannabinoids as anticancer agents

(2016) Guillermo Velasco et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The Use of Medical Marijuana in Cancer

(2016) Shauna M. Birdsall et al.   Current Oncology Reports

Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells

(2016) Katrin Winkler et al.   Oncotarget

Cannabis sativa: The Plant of the Thousand and One Molecules

(2016) Christelle M. Andre et al.   Frontiers in Plant Science

Exploiting Cannabinoid-Induced Cytotoxic Autophagy to Drive Melanoma Cell Death

(2015) Jane L. Armstrong et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Antitumor Activity of Plant-Derived Non-Psychoactive Cannabinoids

(2015) Sean D. McAllister et al.   Journal of Neuroimmune Pharmacology

Effects of Cannabinoids on T-cell Function and Resistance to Infection

(2015) Toby K. Eisenstein et al.   Journal of Neuroimmune Pharmacology

Role of Cannabinoid Receptor CB2 in HER2 Pro-oncogenic Signaling in Breast Cancer

(2015) Eduardo Pérez-Gómez et al.   JNCI-Journal of the National Cancer Institute

Modulation of the tumor microenvironment and inhibition of EGF/EGFR pathway: Novel anti-tumor mechanisms of Cannabidiol in breast cancer

(2015) Mohamad Elbaz et al.   Molecular Oncology

Proapoptotic effect of endocannabinoids in prostate cancer cells

(2015) O. ORELLANA-SERRADELL et al.   ONCOLOGY REPORTS

Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma

(2015) E Singer et al.   Cell Death & Disease

Role of Cannabinoid Receptor CB2 in HER2 Pro-oncogenic Signaling in Breast Cancer

(2015) Eduardo Pérez-Gómez et al.   JNCI-Journal of the National Cancer Institute

Cannabinoids increase lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1

(2014) Maria Haustein et al.   BIOCHEMICAL PHARMACOLOGY

Medical marijuana for cancer

(2014) Joan L. Kramer   CA-A CANCER JOURNAL FOR CLINICIANS

Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid

(2014) Francesca Borrelli et al.   CARCINOGENESIS

Histone Modifications Are Associated with Δ9-Tetrahydrocannabinol-mediated Alterations in Antigen-specific T Cell Responses

(2014) Xiaoming Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The pseudokinase tribbles homologue-3 plays a crucial role in cannabinoid anticancer action

(2013) María Salazar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cannabidiol attenuates deficits of visuospatial associative memory induced by Δ9tetrahydrocannabinol

(2013) M Jerry Wright et al.   BRITISH JOURNAL OF PHARMACOLOGY

Non-THC cannabinoids inhibit prostate carcinoma growthin vitroandin vivo: pro-apoptotic effects and underlying mechanisms

(2012) Luciano De Petrocellis et al.   BRITISH JOURNAL OF PHARMACOLOGY

COX-2 and PPAR-  Confer Cannabidiol-Induced Apoptosis of Human Lung Cancer Cells

(2012) R. Ramer et al.   MOLECULAR CANCER THERAPEUTICS

Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy

(2011) D Vara et al.   CELL DEATH AND DIFFERENTIATION

Update on the endocannabinoid system as an anticancer target

(2011) Anna Maria Malfitano et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma

(2011) S. Torres et al.   MOLECULAR CANCER THERAPEUTICS

Cannabidiol Induces Programmed Cell Death in Breast Cancer Cells by Coordinating the Cross-talk between Apoptosis and Autophagy

(2011) A. Shrivastava et al.   MOLECULAR CANCER THERAPEUTICS

Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism

(2011) M Donadelli et al.   Cell Death & Disease

Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis

(2010) Sean D. McAllister et al.   BREAST CANCER RESEARCH AND TREATMENT

CB2: a cannabinoid receptor with an identity crisis

(2010) Brady K Atwood et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabinoids and the immune system: An overview

(2010) Radu Tanasescu et al.   IMMUNOBIOLOGY

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

(2010) R. G. Pertwee et al.   PHARMACOLOGICAL REVIEWS

Fatty Acid Amide Hydrolase in Prostate Cancer: Association with Disease Severity and Outcome, CB1 Receptor Expression and Regulation by IL-4

(2010) Lina Thors et al.   PLoS One

Cannabinoids, Endocannabinoids, and Related Analogs in Inflammation

(2009) Sumner H. Burstein et al.   AAPS Journal

Emerging strategies for exploiting cannabinoid receptor agonists as medicines

(2009) Roger G Pertwee   BRITISH JOURNAL OF PHARMACOLOGY

Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

(2009) Daniel K. Nomura et al.   CELL

Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression

(2009) Sadiye Amcaoglu Rieder et al.   IMMUNOBIOLOGY

Cannabinoid Receptor Type 1- and 2-mediated Increase in Cyclic AMP Inhibits T Cell Receptor-triggered Signaling

(2009) Christine Börner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

(2009) María Salazar et al.   JOURNAL OF CLINICAL INVESTIGATION

Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer

(2009) Z. Qamri et al.   MOLECULAR CANCER THERAPEUTICS

Synergy research: Approaching a new generation of phytopharmaceuticals

(2009) H. Wagner et al.   PHYTOMEDICINE

The profile of immune modulation by cannabidiol (CBD) involves deregulation of nuclear factor of activated T cells (NFAT)

(2008) Barbara L.F. Kaplan et al.   BIOCHEMICAL PHARMACOLOGY

Loss of Cannabinoid Receptor 1 Accelerates Intestinal Tumor Growth

(2008) D. Wang et al.   CANCER RESEARCH

The Cannabinoid Receptors Are Required for Ultraviolet-Induced Inflammation and Skin Cancer Development

(2008) D. Zheng et al.   CANCER RESEARCH

Cannabinoids for Cancer Treatment: Progress and Promise

(2008) S. Sarfaraz et al.   CANCER RESEARCH

Cannabinoids Inhibit Glioma Cell Invasion by Down-regulating Matrix Metalloproteinase-2 Expression

(2008) C. Blazquez et al.   CANCER RESEARCH

Mechanisms of Control of Neuron Survival by the Endocannabinoid System

(2008) Ismael Galve-Roperh et al.   CURRENT PHARMACEUTICAL DESIGN

Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids: Involvement of Regulatory T Cells

(2008) V. L. Hegde et al.   MOLECULAR PHARMACOLOGY

Endocannabinoid signaling as a synaptic circuit breaker in neurological disease

(2008) István Katona et al.   NATURE MEDICINE

JunD is involved in the antiproliferative effect of Δ9-tetrahydrocannabinol on human breast cancer cells

(2008) M M Caffarel et al.   ONCOGENE

Inhibition of Cancer Cell Invasion by Cannabinoids via Increased Expression of Tissue Inhibitor of Matrix Metalloproteinases-1

(2007) Robert Ramer et al.   JNCI-Journal of the National Cancer Institute