Marine sponge-derived smenospongine preferentially eliminates breast cancer stem-like cells via p38/AMPKα pathways

Sesquiterpene Quinones/Hydroquinones from the Marine Sponge Spongia pertusa Esper

(2017) Jing Li et al.   JOURNAL OF NATURAL PRODUCTS

Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication

(2016) Samantha Kaufhold et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

ErbB2 and p38γ MAPK mediate alcohol-induced increase in breast cancer stem cells and metastasis

(2016) Mei Xu et al.   Molecular Cancer

Magnetic Tandem Apoptosis for Overcoming Multidrug-Resistant Cancer

(2016) Mi Hyeon Cho et al.   NANO LETTERS

Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy

(2016) Prasad R. Dandawate et al.   SEMINARS IN CANCER BIOLOGY

Coexpression of gene Oct4 and Nanog initiates stem cell characteristics in hepatocellular carcinoma and promotes epithelial-mesenchymal transition through activation of Stat3/Snail signaling

(2015) Xin Yin et al.   Journal of Hematology & Oncology

Regulation of NANOG in cancer cells

(2015) Shuai Gong et al.   MOLECULAR CARCINOGENESIS

γ-oryzanol reduces caveolin-1 and PCGEM1 expression, markers of aggressiveness in prostate cancer cell lines

(2015) Gabriela E. Hirsch et al.   PROSTATE

Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell

(2015) Mayuko Nishi et al.   Oncotarget

p38γ Mitogen-Activated Protein Kinase Contributes to Oncogenic Properties Maintenance and Resistance to Poly (ADP-Ribose)-Polymerase-1 Inhibition in Breast Cancer

(2015) Fanyan Meng et al.   NEOPLASIA

Bmi1 regulates self-renewal and epithelial to mesenchymal transition in breast cancer cells through Nanog

(2014) Anurag N Paranjape et al.   BMC CANCER

Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells

(2013) Min-Bin Chen et al.   CELLULAR SIGNALLING

The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis

(2013) X Lu et al.   ONCOGENE

Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers

(2012) M K Y Siu et al.   ONCOGENE

Glioma-Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK

(2012) Atsushi Sato et al.   Stem Cells Translational Medicine

Over-expression of Sox2 in C3H10T1/2 cells inhibits osteoblast differentiation through Wnt and MAPK signalling pathways

(2011) Daofang Ding et al.   INTERNATIONAL ORTHOPAEDICS

Antiproliferative and Antiangiogenic Activities of Smenospongine, a Marine Sponge Sesquiterpene Aminoquinone

(2011) Dexin Kong et al.   Marine Drugs

In vitro generation of human cells with cancer stem cell properties

(2011) Paola Scaffidi et al.   NATURE CELL BIOLOGY

Sox2 expression in breast tumours and activation in breast cancer stem cells

(2011) O Leis et al.   ONCOGENE

Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancer

(2010) Hui-Min Meng et al.   CANCER BIOLOGY & THERAPY

Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell-Like Properties and Epithelial-Mesenchymal Transdifferentiation

(2010) S.-H. Chiou et al.   CANCER RESEARCH

Molecular biology of breast cancer stem cells: Potential clinical applications

(2010) Nam P. Nguyen et al.   CANCER TREATMENT REVIEWS

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Positive Correlations of Oct-4 and Nanog in Oral Cancer Stem-Like Cells and High-Grade Oral Squamous Cell Carcinoma

(2008) S.-H. Chiou et al.   CLINICAL CANCER RESEARCH

Survival of the Fittest: Cancer Stem Cells in Therapeutic Resistance and Angiogenesis

(2008) Christine E. Eyler et al.   JOURNAL OF CLINICAL ONCOLOGY

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute