Article
Medicine, General & Internal
Kyung-Min Ahn, Byung-Keun Kim, Min-Suk Yang
Summary: Drug-induced anaphylaxis is a fatal medical condition with increasing incidence. This study investigated culprit drugs and common medication risk factors for drug-induced anaphylaxis in the Korean general population. By analyzing medical prescription histories in the Health Insurance Service and Assessment Service database, 5 common medication risk factors were identified.
Article
Public, Environmental & Occupational Health
Keiji Muramatsu, Hanaka Imamura, Kei Tokutsu, Kenji Fujimoto, Kiyohide Fushimi, Shinya Matsuda
Summary: This study aimed to identify foods that cause food-induced anaphylaxis (FIA) in Japan. The results revealed that eggs were the most common causative food, and the main causative food varied among different age groups. It was found that peanut-induced FIA has become as common in Japan as it is in the West. These findings highlight the importance of preventing peanut allergies.
JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Medicine, General & Internal
Xujing Liu, Aihua Zhai, Bai Zhang
Summary: This case study discusses the anaphylactic shock caused by reexposure to exenatide after interruption of treatment. The study highlights the immunogenicity of exenatide and the importance of considering the possibility of anaphylactic shock in patients receiving exenatide treatment.
Article
Allergy
R. Casas-Saucedo, C. de la Cruz, G. Araujo-Sanchez, S. Gelis, T. Jimenez, S. Riggioni, C. San Bartolome, M. Pascal, J. Bartra Tomas, R. Munoz-Cano
Summary: The study aimed to identify risk factors in patients who experience anaphylactic shock. Using lipid transfer protein (LTP) allergy as a model, the characteristics of patients who developed anaphylaxis and anaphylactic shock were compared. The results showed that patients in the anaphylaxis group experienced more reactions than those in the anaphylactic shock group. There was no relationship between different food groups and the severity of the reaction. The most frequent food involved in both groups was a combination of several plant-derived foods. Anaphylactic shock seems to be associated with other individual-related factors requiring further evaluation.
JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
(2022)
Article
Allergy
Sakura Sato, Noriyuki Yanagida, Komei Ito, Yoshitaka Okamoto, Hirohisa Saito, Masami Taniguchi, Makoto Nagata, Hirokuni Hirata, Masao Yamaguchi, Ruby Pawankar, Motohiro Ebisawa
Summary: This study conducted the first nationwide epidemiological survey on anaphylaxis in Japan. The results showed that children were the main population affected by anaphylaxis, with food and drugs being the most common triggers. Intramuscular injection of adrenaline was commonly used for treatment. The findings highlight the importance of comprehensive education and training on anaphylaxis.
ALLERGOLOGY INTERNATIONAL
(2023)
Article
Multidisciplinary Sciences
Mohammad Altermanini, Mohamad Hijazi, Tarek Aboursheid, Muhammad Firas Alhammad, Khaled Ali, Elias Tayar, Ramsey Jasim
Summary: This article presents a rare case of anaphylaxis due to worm infestation, where a young gentleman had extremely high levels of procalcitonin (PCT), a well-known biomarker for bacterial infection.
Article
Immunology
Fotini Boufidou, Sophia Hatziantoniou, Kalliopi Theodoridou, Helena C. C. Maltezou, Konstantinos Vasileiou, Cleo Anastassopoulou, Snezana Medic, Athanasios Tsakris
Summary: This study provides an updated assessment of anaphylaxis incidence associated with COVID-19 vaccines based on pharmacovigilance data. The latest analysis shows a lower incidence of anaphylactic reaction and anaphylactic shock compared to previous estimates. The study also highlights the importance of continuous monitoring through specialized pharmacovigilance databases for ensuring the safety of COVID-19 vaccines.
Article
Allergy
Theresa Hanschmann, Wojciech Francuzik, Sabine Doelle-Bierke, Kathrin Scherer Hofmeier, Linus Grabenhenrich, Franziska Rueff, Jean-Marie Renaudin, Claudia Pfoehler, Regina Treudler, M. Beatrice Bilo, Roland Lang, Luis Felipe Ensina, George Christoff, Victoria Cardona, Nicola Wagner, Norbert Reider, Sabine Mueller, Heinrich Dickel, Margitta Worm
Summary: This study analyzes a large dataset on drug induced anaphylaxis and provides insights into its causes, risk factors, symptoms, and treatment. Drugs, particularly analgesics and antibiotics, are found to be the third most common cause of anaphylactic reactions. Female gender and older age are identified as relevant risk factors, while children are less affected by drug induced anaphylaxis.
Article
Allergy
Isaku Kurotori, Takashi Kimura, Wataru Sasao, Masahiko Abe, Hideki Kumagai, Akiko Tamakoshi
Summary: Fishery workers in Hokkaido involved in scallop aquaculture are at risk of natto allergy, and this risk is associated with age, experience in repairing nets, and length of work experience.
ALLERGOLOGY INTERNATIONAL
(2023)
Article
Allergy
Sevim Bavbek, Secil Kepil Ozdemir, Patrizia Bonadonna, Marina Atanaskovic-Markovic, Annick Barbaud, Knut Brockow, Jose Laguna Martinez, Alla Nakonechna, Mauro Pagani, Alessandra Arcolaci, Carla Lombardo, Maria J. Torres
Summary: This paper provides evidence-based recommendations for the diagnosis and management of hypersensitivity reactions (HSRs) to proton pump inhibitors (PPIs), and calls for further in-depth research.
Review
Allergy
Kaitlin B. Proctor, Katherine Tison, Hayley H. Estrem, Jinhee Park, Lawrence Scahill, Brian P. Vickery, William G. Sharp
Summary: The systematic review evaluated parent report measures assessing the psychosocial impact of pediatric IgE-mediated FA, finding that while available measures show some evidence of reliability and validity, none completely adhere to PROMIS guidelines. The results emphasize the need for further research to develop a measurement approach that assesses the full range of psychosocial impact that parents and families may experience as a result of FA, and also serve as a research outcome to help the field continue to develop effective treatments, including immunotherapy.
Review
Allergy
Paul J. Turner, Stefania Arasi, Barbara Ballmer-Weber, Alessia Baseggio Conrado, Antoine Deschildre, Jennifer Gerdts, Susanne Halken, Antonella Muraro, Nandinee Patel, Ronald Van Ree, Debra de Silva, Margitta Worm, Torsten Zuberbier, Graham Roberts
Summary: This study summarizes the latest evidence on risk factors for severe food-induced allergic reactions. The study found significant uncertainties in predicting severe reactions and identified some molecular allergology markers that may be helpful. Age was identified as an important factor in severe reactions, but the contribution of risk-taking behavior remains unclear.
Review
Immunology
Alessandra Vultaggio, Margherita Perlato, Francesca Nencini, Emanuele Vivarelli, Enrico Maggi, Andrea Matucci
Summary: Biologicals are commonly used for rheumatologic diseases, cancers, and chronic inflammatory conditions, but they may lead to the development of anti-drug antibodies (ADA), limiting their clinical usage due to safety concerns. Strategies such as concomitant immunosuppressive treatment and regular infusion regimens can help reduce the risk of immediate hypersensitivity reactions (HSRs) associated with ADA. Drug desensitization (DD) may be considered for patients needing reintroduction of the biological culprit, especially in cases of IgE-mediated HSRs, potentially inhibiting mast cell degranulation and cytokine production.
FRONTIERS IN IMMUNOLOGY
(2021)
Review
Allergy
Irene Mikhail, David R. Stukus, Benjamin T. Prince
Summary: This review aims to help clinicians understand the risk factors associated with fatal anaphylaxis and to promote personalized management plans based on individual clinical histories. Anaphylaxis is a rapidly progressive systemic reaction with various triggers and severity levels, requiring tailored counseling and management strategies for each patient.
CURRENT ALLERGY AND ASTHMA REPORTS
(2021)
Article
Oncology
Nobuyuki Horita, Etsuko Miyagi, Taichi Mizushima, Maki Hagihara, Chiaki Hata, Yuki Hattori, Narihiko Hayashi, Kuniyasu Irie, Hideyuki Ishikawa, Yusuke Kawabata, Yosuke Kitani, Noritoshi Kobayashi, Nobuaki Kobayashi, Yusuke Kurita, Yohei Miyake, Kentaro Miyake, Senri Oguri, Ichiro Ota, Ayako Shimizu, Masanobu Takeuchi, Akimitsu Yamada, Kojiro Yamamoto, Norio Yukawa, Munetaka Masuda, Nobuhiko Oridate, Yasushi Ichikawa, Takeshi Kaneko
Summary: This study examined the incidence and risk factors of severe anaphylaxis induced by intravenous chemotherapy in cancer patients. A total of 27 cases of severe anaphylaxis were observed among 5584 patients, with drugs like carboplatin and paclitaxel being the main culprits. The study highlighted the high-risk settings associated with these severe allergic reactions.