Current Progress and Challenges for Skeletal Muscle Differentiation from Human Pluripotent Stem Cells Using Transgene-Free Approaches

Engineering human pluripotent stem cells into a functional skeletal muscle tissue

(2018) Lingjun Rao et al.   Nature Communications

ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs

(2017) Michael R. Hicks et al.   NATURE CELL BIOLOGY

PAX7 Targets, CD54, Integrin α9β1, and SDC2, Allow Isolation of Human ESC/iPSC-Derived Myogenic Progenitors

(2017) Alessandro Magli et al.   Cell Reports

In Vivo Human Somitogenesis Guides Somite Development from hPSCs

(2017) Haibin Xi et al.   Cell Reports

Skeletal Muscle Cell Induction from Pluripotent Stem Cells

(2017) Yusaku Kodaka et al.   Stem Cells International

Expansion and Purification Are Critical for the Therapeutic Application of Pluripotent Stem Cell-Derived Myogenic Progenitors

(2017) Jaemin Kim et al.   Stem Cell Reports

Robust generation and expansion of skeletal muscle progenitors and myocytes from human pluripotent stem cells

(2016) Michael Shelton et al.   METHODS

Generation of human muscle fibers and satellite-like cells from human pluripotent stem cells in vitro

(2016) Jérome Chal et al.   Nature Protocols

Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model

(2016) In Young Choi et al.   Cell Reports

A Novel Protocol for Directed Differentiation of C9orf72-Associated Human Induced Pluripotent Stem Cells Into Contractile Skeletal Myotubes

(2016) Elliot W. Swartz et al.   Stem Cells Translational Medicine

A Human Pluripotent Stem Cell Model of Facioscapulohumeral Muscular Dystrophy-Affected Skeletal Muscles

(2016) Leslie Caron et al.   Stem Cells Translational Medicine

Skeletal muscle fiber type: using insights from muscle developmental biology to dissect targets for susceptibility and resistance to muscle disease

(2016) Jared Talbot et al.   Wiley Interdisciplinary Reviews-Developmental Biology

The Role of Notch Receptors in Transcriptional Regulation

(2015) Hongfang Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

WNT/β-Catenin Signaling Regulates Multiple Steps of Myogenesis by Regulating Step-Specific Targets

(2015) Akiko Suzuki et al.   MOLECULAR AND CELLULAR BIOLOGY

Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy

(2015) Jérome Chal et al.   NATURE BIOTECHNOLOGY

Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells

(2015) Christoph Patsch et al.   NATURE CELL BIOLOGY

Efficient derivation and inducible differentiation of expandable skeletal myogenic cells from human ES and patient-specific iPS cells

(2015) Sara M Maffioletti et al.   Nature Protocols

PAX3 and PAX7 as upstream regulators of myogenesis

(2015) Margaret Buckingham et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Identification of Small Molecules Which Induce Skeletal Muscle Differentiation in Embryonic Stem Cells via Activation of the Wnt and Inhibition of Smad2/3 and Sonic Hedgehog Pathways

(2015) Hyunwoo Lee et al.   STEM CELLS

Myogenic Precursors from iPS Cells for Skeletal Muscle Cell Replacement Therapy

(2015) Isart Roca et al.   Journal of Clinical Medicine

Functional analysis of iPSC-derived myocytes from a patient with carnitine palmitoyltransferase II deficiency

(2014) Tetsuhiko Yasuno et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Micropattern width dependent sarcomere development in human ESC-derived cardiomyocytes

(2014) Max R. Salick et al.   BIOMATERIALS

Small Molecules Dorsomorphin and LDN-193189 Inhibit Myostatin/GDF8 Signaling and Promote Functional Myoblast Differentiation

(2014) Daniel Horbelt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physiological and ultrastructural features of human induced pluripotent and embryonic stem cell-derived skeletal myocytes in vitro

(2014) G. Skoglund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Derivation of Myogenic Progenitors Directly From Human Pluripotent Stem Cells Using a Sphere-Based Culture

(2014) Tohru Hosoyama et al.   Stem Cells Translational Medicine

Myogenic Differentiation of Muscular Dystrophy-Specific Induced Pluripotent Stem Cells for Use in Drug Discovery

(2014) Ramzey Abujarour et al.   Stem Cells Translational Medicine

Isolation of Progenitors that Exhibit Myogenic/Osteogenic Bipotency In Vitro by Fluorescence-Activated Cell Sorting from Human Fetal Muscle

(2014) Alessandra Castiglioni et al.   Stem Cell Reports

Derivation and Expansion of PAX7-Positive Muscle Progenitors from Human and Mouse Embryonic Stem Cells

(2014) Michael Shelton et al.   Stem Cell Reports

Use of Flow, Electrical, and Mechanical Stimulation to Promote Engineering of Striated Muscles

(2013) Swathi Rangarajan et al.   ANNALS OF BIOMEDICAL ENGINEERING

A Zebrafish Embryo Culture System Defines Factors that Promote Vertebrate Myogenesis across Species

(2013) Cong Xu et al.   CELL

Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro

(2013) Akihito Tanaka et al.   PLoS One

Directed In Vitro Myogenesis of Human Embryonic Stem Cells and Their In Vivo Engraftment

(2013) Yongsung Hwang et al.   PLoS One

Skeletal Muscle Tissue Engineering: Methods to Form Skeletal Myotubes and Their Applications

(2013) Serge Ostrovidov et al.   TISSUE ENGINEERING PART B-REVIEWS

Stem cells for skeletal muscle regeneration: therapeutic potential and roadblocks

(2013) Fabrizio Rinaldi et al.   Translational Research

Electrical stimulation as a biomimicry tool for regulating muscle cell behavior

(2013) Samad Ahadian et al.   Organogenesis

In vitro differentiation of functional human skeletal myotubes in a defined system

(2013) Xiufang Guo et al.   Biomaterials Science

Derivation and FACS-Mediated Purification of PAX3+/PAX7+ Skeletal Muscle Precursors from Human Pluripotent Stem Cells

(2013) Bianca Borchin et al.   Stem Cell Reports

Human ES- and iPS-Derived Myogenic Progenitors Restore DYSTROPHIN and Improve Contractility upon Transplantation in Dystrophic Mice

(2012) Radbod Darabi et al.   Cell Stem Cell

Murine GASP-1N-Glycosylation is not Essential for its Activity on C2C12 Myogenic Cells but Alters its Secretion

(2012) Caroline Brun et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Selective Development of Myogenic Mesenchymal Cells from Human Embryonic and Induced Pluripotent Stem Cells

(2012) Tomonari Awaya et al.   PLoS One

Building Muscle: Molecular Regulation of Myogenesis

(2012) C. F. Bentzinger et al.   Cold Spring Harbor Perspectives in Biology

Follistatin Improves Skeletal Muscle Healing after Injury and Disease through an Interaction with Muscle Regeneration, Angiogenesis, and Fibrosis

(2011) Jinhong Zhu et al.   AMERICAN JOURNAL OF PATHOLOGY

Neural crest regulates myogenesis through the transient activation of NOTCH

(2011) Anne C. Rios et al.   NATURE

CREB Is Activated by Muscle Injury and Promotes Muscle Regeneration

(2011) Randi Stewart et al.   PLoS One

The Role of GH and IGF-I in Mediating Anabolic Effects of Testosterone on Androgen-Responsive Muscle

(2010) Carlo Serra et al.   ENDOCRINOLOGY

Identification of Retinoic Acid in a High Content Screen for Agents that Overcome the Anti-Myogenic Effect of TGF-Beta-1

(2010) Chateen Krueger et al.   PLoS One

Hierarchization of Myogenic and Adipogenic Progenitors Within Human Skeletal Muscle

(2010) Didier F. Pisani et al.   STEM CELLS

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program

(2008) M. Lagha et al.   GENES & DEVELOPMENT

Cell Therapies for Muscular Dystrophy

(2008) Helen M. Blau   NEW ENGLAND JOURNAL OF MEDICINE