A Novel Protocol for Directed Differentiation of C9orf72-Associated Human Induced Pluripotent Stem Cells Into Contractile Skeletal Myotubes

Isoform-specific antibodies reveal distinct subcellular localizations of C9orf72 in amyotrophic lateral sclerosis

(2015) Shangxi Xiao et al.   ANNALS OF NEUROLOGY

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport

(2015) Ke Zhang et al.   NATURE

GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport

(2015) Brian D. Freibaum et al.   NATURE

Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy

(2015) Jérome Chal et al.   NATURE BIOTECHNOLOGY

A qPCR ScoreCard quantifies the differentiation potential of human pluripotent stem cells

(2015) Alexander M Tsankov et al.   NATURE BIOTECHNOLOGY

Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS

(2015) Mercedes Prudencio et al.   NATURE NEUROSCIENCE

Efficient derivation and inducible differentiation of expandable skeletal myogenic cells from human ES and patient-specific iPS cells

(2015) Sara M Maffioletti et al.   Nature Protocols

Increased Stiffness in Aged Skeletal Muscle Impairs Muscle Progenitor Cell Proliferative Activity

(2015) Grégory Lacraz et al.   PLoS One

Insights into Muscle Degeneration from Heritable Inclusion Body Myopathies

(2015) Sabine Krause   Frontiers in Aging Neuroscience

Increased microenvironment stiffness in damaged myofibers promotes myogenic progenitor cell proliferation

(2015) Frédéric Trensz et al.   Skeletal Muscle

C9ORF72-ALS: P62- and ubiquitin-aggregation pathology in skeletal muscle

(2014) Matthias Türk et al.   MUSCLE & NERVE

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

(2014) Benjamin D Cosgrove et al.   NATURE MEDICINE

Derivation of Myogenic Progenitors Directly From Human Pluripotent Stem Cells Using a Sphere-Based Culture

(2014) Tohru Hosoyama et al.   Stem Cells Translational Medicine

Myogenic Differentiation of Muscular Dystrophy-Specific Induced Pluripotent Stem Cells for Use in Drug Discovery

(2014) Ramzey Abujarour et al.   Stem Cells Translational Medicine

Derivation and Expansion of PAX7-Positive Muscle Progenitors from Human and Mouse Embryonic Stem Cells

(2014) Michael Shelton et al.   Stem Cell Reports

A simple tool to improve pluripotent stem cell differentiation

(2013) Sundari Chetty et al.   NATURE METHODS

The mouse C9ORF72 ortholog is enriched in neurons known to degenerate in ALS and FTD

(2013) Naoki Suzuki et al.   NATURE NEUROSCIENCE

RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention

(2013) Christopher J. Donnelly et al.   NEURON

Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis

(2013) Shuo-Chien Ling et al.   NEURON

Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion

(2013) D. Sareen et al.   Science Translational Medicine

Efficient Derivation of Lateral Plate and Paraxial Mesoderm Subtypes from Human Embryonic Stem Cells Through GSKi-Mediated Differentiation

(2013) Jia Yong Tan et al.   STEM CELLS AND DEVELOPMENT

Signals and Switches in Mammalian Neural Crest Cell Differentiation

(2013) S. Bhatt et al.   Cold Spring Harbor Perspectives in Biology

Epigenetic Reprogramming of Human Embryonic Stem Cells into Skeletal Muscle Cells and Generation of Contractile Myospheres

(2013) Sonia Albini et al.   Cell Reports

Derivation and FACS-Mediated Purification of PAX3+/PAX7+ Skeletal Muscle Precursors from Human Pluripotent Stem Cells

(2013) Bianca Borchin et al.   Stem Cell Reports

Human ES- and iPS-Derived Myogenic Progenitors Restore DYSTROPHIN and Improve Contractility upon Transplantation in Dystrophic Mice

(2012) Radbod Darabi et al.   Cell Stem Cell

Assessing iPSC reprogramming methods for their suitability in translational medicine

(2012) Mahendra S. Rao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Myoblasts Derived From Normal hESCs and Dystrophic hiPSCs Efficiently Fuse With Existing Muscle Fibers Following Transplantation

(2012) Sébastien Goudenege et al.   MOLECULAR THERAPY

Generation of human vascular smooth muscle subtypes provides insight into embryological origin–dependent disease susceptibility

(2012) Christine Cheung et al.   NATURE BIOTECHNOLOGY

Substrate stiffness affects skeletal myoblast differentiationin vitro

(2012) Sara Romanazzo et al.   SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS

Building Muscle: Molecular Regulation of Myogenesis

(2012) C. F. Bentzinger et al.   Cold Spring Harbor Perspectives in Biology

Marking the tempo for myogenesis: Pax7 and the regulation of muscle stem cell fate decisions

(2011) Hugo C. Olguín et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Multiple Faces of Valosin-Containing Protein-Associated Diseases: Inclusion Body Myopathy with Paget’s Disease of Bone, Frontotemporal Dementia, and Amyotrophic Lateral Sclerosis

(2011) Angèle Nalbandian et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

A bioinformatic assay for pluripotency in human cells

(2011) Franz-Josef Müller et al.   NATURE METHODS

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

(2011) Mariely DeJesus-Hernandez et al.   NEURON

Retinoic Acid Enhances Skeletal Myogenesis in Human Embryonic Stem Cells by Expanding the Premyogenic Progenitor Population

(2011) Tammy Ryan et al.   Stem Cell Reviews and Reports

Assessment of the Myogenic Stem Cell Compartment Following Transplantation ofPax3/Pax7-Induced Embryonic Stem Cell-Derived Progenitors

(2011) Radbod Darabi et al.   STEM CELLS

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Explorations in statistics: the bootstrap

(2009) Douglas Curran-Everett   ADVANCES IN PHYSIOLOGY EDUCATION

Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Distinguished by Gene Expression Signatures

(2009) Mark H. Chin et al.   Cell Stem Cell

Wnt7a Activates the Planar Cell Polarity Pathway to Drive the Symmetric Expansion of Satellite Stem Cells

(2009) Fabien Le Grand et al.   Cell Stem Cell

Neuromuscular junction destruction during amyotrophic lateral sclerosis: insights from transgenic models

(2009) Luc Dupuis et al.   CURRENT OPINION IN PHARMACOLOGY

A home away from home: Challenges and opportunities in engineering in vitro muscle satellite cell niches

(2009) Benjamin D. Cosgrove et al.   DIFFERENTIATION

The elastic modulus of Matrigel™ as determined by atomic force microscopy

(2009) Shauheen S. Soofi et al.   JOURNAL OF STRUCTURAL BIOLOGY

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

(2009) Akiko Doi et al.   NATURE GENETICS

Signaling Gradients during Paraxial Mesoderm Development

(2009) A. Aulehla et al.   Cold Spring Harbor Perspectives in Biology

Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated

(2008) Shao H. Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional skeletal muscle regeneration from differentiating embryonic stem cells

(2008) Radbod Darabi et al.   NATURE MEDICINE

Paraxial Mesodermal Progenitors Derived from Mouse Embryonic Stem Cells Contribute to Muscle Regeneration via Differentiation into Muscle Satellite Cells

(2008) Hidetoshi Sakurai et al.   STEM CELLS