Analysis of the Paternally-Imprinted DLK1–MEG3 and IGF2–H19 Tandem Gene Loci in NT2 Embryonal Carcinoma Cells Identifies DLK1 as a Potential Therapeutic Target
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Title
Analysis of the Paternally-Imprinted DLK1–MEG3 and IGF2–H19 Tandem Gene Loci in NT2 Embryonal Carcinoma Cells Identifies DLK1 as a Potential Therapeutic Target
Authors
Keywords
Imprinting, DLK1, Embryonal carcinoma, Pluripotency, Primordial germ cells, Teratocarcinoma, Proliferation, Metastasis, 5-azaD
Journal
Stem Cell Reviews and Reports
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2018-07-06
DOI
10.1007/s12015-018-9838-5
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- (2016) Pengxu Qian et al. Cell Stem Cell
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- (2015) MACIEJ TARNOWSKI et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- The knockdown of H19lncRNA reveals its regulatory role in pluripotency and tumorigenesis of human embryonic carcinoma cells
- (2015) Evelyne Zeira et al. Oncotarget
- Germ Cell Tumors of the Ovary: An Update
- (2014) Francisco F. Nogales et al. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
- Aza-deoxycytidine induces apoptosis or differentiation via DNMT3B and targets embryonal carcinoma cells but not their differentiated derivatives
- (2014) P Wongtrakoongate et al. BRITISH JOURNAL OF CANCER
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- (2013) GABRIELA SCHNEIDER et al. INTERNATIONAL JOURNAL OF ONCOLOGY
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- (2013) Asma Begum et al. MOLECULAR CANCER RESEARCH
- Maternal imprinting at the H19–Igf2 locus maintains adult haematopoietic stem cell quiescence
- (2013) Aparna Venkatraman et al. NATURE
- Physiological Oxygen Prevents Frequent Silencing of theDLK1-DIO3Cluster during Human Embryonic Stem Cells Culture
- (2013) Pingyuan Xie et al. STEM CELLS
- The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r
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- Acute Hypersensitivity of Pluripotent Testicular Cancer-Derived Embryonal Carcinoma to Low-Dose 5-Aza Deoxycytidine Is Associated with Global DNA Damage-Associated p53 Activation, Anti-Pluripotency and DNA Demethylation
- (2012) Bijesh K. Biswal et al. PLoS One
- Primordial Germ Cells in Mice
- (2012) M. Saitou et al. Cold Spring Harbor Perspectives in Biology
- DLK1, delta-like 1 homolog (Drosophila), regulates tumor cell differentiation in vivo
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- (2010) Cynthia Gomes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
- (2010) Matthias Stadtfeld et al. NATURE
- Effect of retinoic acid and delta-like 1 homologue (DLK1) on differentiation in neuroblastoma
- (2010) Yuri Kim Nutrition Research and Practice
- Hypoxia-Regulated Delta-like 1 Homologue Enhances Cancer Cell Stemness and Tumorigenicity
- (2009) Y. Kim et al. CANCER RESEARCH
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