Use of Haploid Model of Candida albicans to Uncover Mechanism of Action of a Novel Antifungal Agent

Nerol triggers mitochondrial dysfunction and disruption via elevation of Ca 2+ and ROS in Candida albicans

(2017) Jun Tian et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Scolopendin, an antimicrobial peptide from centipede, attenuates mitochondrial functions and triggers apoptosis in Candida albicans

(2016) Heejeong Lee et al.   BIOCHEMICAL JOURNAL

Comparative Ploidy Proteomics ofCandida albicansBiofilms Unraveled the Role of theAHP1Gene in the Biofilm Persistence Against Amphotericin B

(2016) Thuyen Truong et al.   MOLECULAR & CELLULAR PROTEOMICS

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

(2015) Kıvanç Birsoy et al.   CELL

Clinical perspectives on echinocandin resistance among Candida species

(2015) Ryan K. Shields et al.   CURRENT OPINION IN INFECTIOUS DISEASES

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

New “haploid biofilm model” unravels IRA2 as a novel regulator of Candida albicans biofilm formation

(2015) Chaminda Jayampath Seneviratne et al.   Scientific Reports

Budding Yeast for Budding Geneticists: A Primer on the Saccharomyces cerevisiae Model System

(2014) Andrea A. Duina et al.   GENETICS

One-step targeted gene deletion in Candida albicans haploids

(2014) Guisheng Zeng et al.   Nature Protocols

In Vitro and In Vivo Activity of a Novel Antifungal Small Molecule against Candida Infections

(2014) Sarah Sze Wah Wong et al.   PLoS One

Regulatory Networks Controlling Nitrogen Sensing and Uptake in Candida albicans

(2014) Shruthi Ramachandra et al.   PLoS One

Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels

(2014) Alistair J.P. Brown et al.   TRENDS IN MICROBIOLOGY

Mitochondrial Two-Component Signaling Systems in Candida albicans

(2013) John Mavrianos et al.   EUKARYOTIC CELL

The ‘obligate diploid’ Candida albicans forms mating-competent haploids

(2013) Meleah A. Hickman et al.   NATURE

Generation of Genetically Modified Mice by Oocyte Injection of Androgenetic Haploid Embryonic Stem Cells

(2012) Hui Yang et al.   CELL

Mitochondria and Mitophagy

(2012) Dieter A. Kubli et al.   CIRCULATION RESEARCH

Mating-Type Genes and MAT Switching in Saccharomyces cerevisiae

(2012) J. E. Haber   GENETICS

Failure of Amino Acid Homeostasis Causes Cell Death following Proteasome Inhibition

(2012) Amila Suraweera et al.   MOLECULAR CELL

Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells

(2011) Ulrich Elling et al.   Cell Stem Cell

Mitochondria and Fungal Pathogenesis: Drug Tolerance, Virulence, and Potential for Antifungal Therapy

(2011) Miguel Shingu-Vazquez et al.   EUKARYOTIC CELL

The Regulation and Physiology of Mitochondrial Proton Leak

(2011) Ajit S. Divakaruni et al.   PHYSIOLOGY

Pathogenesis and treatment of oral candidosis

(2011) David Williams et al.   Journal of Oral Microbiology

Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2

(2010) Michael J. Dagley et al.   MOLECULAR MICROBIOLOGY

Pathway analysis of Candida albicans survival and virulence determinants in a murine infection model

(2010) J. M. Becker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essentials for ATP Synthesis by F1F0ATP Synthases

(2009) Christoph von Ballmoos et al.   Annual Review of Biochemistry

Hypersusceptibility to Azole Antifungals in a Clinical Isolate of Candida glabrata with Reduced Aerobic Growth

(2009) P. Vandeputte et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Goa1p ofCandida albicansLocalizes to the Mitochondria during Stress and Is Required for Mitochondrial Function and Virulence

(2009) Adrienne Bambach et al.   EUKARYOTIC CELL

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Reactive oxygen species and yeast apoptosis

(2008) Gabriel G. Perrone et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Cytochrome c: functions beyond respiration

(2008) Yong-Ling P. Ow et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY