Dynamic action of the Sec machinery during initiation, protein translocation and termination

Long-Lived Folding Intermediates Predominate the Targeting-Competent Secretome

(2018) Alexandra Tsirigotaki et al.   STRUCTURE

Protein translocation: what's the problem?

(2016) R. A. Corey et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Photon-HDF5: An Open File Format for Timestamp-Based Single-Molecule Fluorescence Experiments

(2016) Antonino Ingargiola et al.   BIOPHYSICAL JOURNAL

Toward a structural understanding of co-translational protein translocation

(2016) Rebecca M Voorhees et al.   CURRENT OPINION IN CELL BIOLOGY

Crystal structure of a substrate-engaged SecY protein-translocation channel

(2016) Long Li et al.   NATURE

Skp is a multivalent chaperone of outer-membrane proteins

(2016) Bob Schiffrin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Unlocking the Bacterial SecY Translocon

(2016) Robin A. Corey et al.   STRUCTURE

Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon

(2016) Ahmad Jomaa et al.   Nature Communications

Skp is a multivalent chaperone of outer-membrane proteins

(2016) Bob Schiffrin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation

(2016) William John Allen et al.   eLife

FRETBursts: An Open Source Toolkit for Analysis of Freely-Diffusing Single-Molecule FRET

(2016) Antonino Ingargiola et al.   PLoS One

Quantitative Interpretation of FRET Experiments via Molecular Simulation: Force Field and Validation

(2015) Robert B. Best et al.   BIOPHYSICAL JOURNAL

iSMS: single-molecule FRET microscopy software

(2015) Søren Preus et al.   NATURE METHODS

Channel crossing: how are proteins shipped across the bacterial plasma membrane?

(2015) Ian Collinson et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Crystal Structures of SecYEG in Lipidic Cubic Phase Elucidate a Precise Resting and a Peptide-Bound State

(2015) Yoshiki Tanaka et al.   Cell Reports

A “Push and Slide” Mechanism Allows Sequence-Insensitive Translocation of Secretory Proteins by the SecA ATPase

(2014) Benedikt W. Bauer et al.   CELL

Domain movements of the enhancer-dependent sigma factor drive DNA delivery into the RNA polymerase active site: insights from single molecule studies

(2014) Amit Sharma et al.   NUCLEIC ACIDS RESEARCH

Mobility of the SecA 2-helix-finger is not essential for polypeptide translocation via the SecYEG complex

(2012) Sarah Whitehouse et al.   JOURNAL OF CELL BIOLOGY

Development of new photon-counting detectors for single-molecule fluorescence microscopy

(2012) X. Michalet et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Structure of the SecY Complex Unlocked by a Preprotein Mimic

(2012) Dilem Hizlan et al.   Cell Reports

Identifying Molecular Dynamics in Single-Molecule FRET Experiments with Burst Variance Analysis

(2011) Joseph P. Torella et al.   BIOPHYSICAL JOURNAL

Quantifying heterogeneity and conformational dynamics from single molecule FRET of diffusing molecules: recurrence analysis of single particles (RASP)

(2011) Armin Hoffmann et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

The Oligomeric State and Arrangement of the Active Bacterial Translocon

(2010) Karine Deville et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial Sec Protein Transport Is Rate-limited by Precursor Length: A Single Turnover Study

(2009) Fu-Cheng Liang et al.   MOLECULAR BIOLOGY OF THE CELL

Signal peptides are allosteric activators of the protein translocase

(2009) Giorgos Gouridis et al.   NATURE

Energy transduction in protein transport and the ATP hydrolytic cycle of SecA

(2009) A. Robson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic peptides identify a second periplasmic site for the plug of the SecYEG protein translocation complex

(2008) Alice Robson et al.   FEBS LETTERS

Analysis of Polypeptide Movement in the SecY Channel during SecA-mediated Protein Translocation

(2008) Karl J. Erlandson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of a complex of the ATPase SecA and the protein-translocation channel

(2008) Jochen Zimmer et al.   NATURE

An Oxygen Scavenging System for Improvement of Dye Stability in Single-Molecule Fluorescence Experiments

(2007) Colin Echeverría Aitken et al.   BIOPHYSICAL JOURNAL