Orphan receptor GPR158 controls stress-induced depression

Gpr158 mediates osteocalcin’s regulation of cognition

(2017) Lori Khrimian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NMDAR inhibition-independent antidepressant actions of ketamine metabolites

(2016) Panos Zanos et al.   NATURE

BDNF – a key transducer of antidepressant effects

(2016) Carl Björkholm et al.   NEUROPHARMACOLOGY

Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain

(2015) Cesare Orlandi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ProLuCID: An improved SEQUEST-like algorithm with enhanced sensitivity and specificity

(2015) T. Xu et al.   Journal of Proteomics

Somatostatin, neuronal vulnerability and behavioral emotionality

(2015) L C Lin et al.   MOLECULAR PSYCHIATRY

Social deficits in IRSp53 mutant mice improved by NMDAR and mGluR5 suppression

(2015) Woosuk Chung et al.   NATURE NEUROSCIENCE

Stress weakens prefrontal networks: molecular insults to higher cognition

(2015) Amy F T Arnsten   NATURE NEUROSCIENCE

Glucocorticoids and Stress-Induced Changes in the Expression of PERIOD1 in the Rat Forebrain

(2015) Sherin Al-Safadi et al.   PLoS One

Optogenetic stimulation of infralimbic PFC reproduces ketamine’s rapid and sustained antidepressant actions

(2015) Manabu Fuchikami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors

(2015) Prerana Shrestha et al.   eLife

Acute and chronic stress differentially regulate cyclin-dependent kinase 5 in mouse brain: implications to glucocorticoid actions and major depression

(2015) A Papadopoulou et al.   Translational Psychiatry

HuD Interacts with Bdnf mRNA and Is Essential for Activity-Induced BDNF Synthesis in Dendrites

(2015) Filip Vanevski et al.   PLoS One

GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine

(2014) Oliver H Miller et al.   eLife

Neuropathology of stress

(2013) Paul J. Lucassen et al.   ACTA NEUROPATHOLOGICA

Repeated Ketamine Exposure Induces an Enduring Resilient Phenotype in Adolescent and Adult Rats

(2013) Eric M. Parise et al.   BIOLOGICAL PSYCHIATRY

Ketamine-induced antidepressant effects are associated with AMPA receptors-mediated upregulation of mTOR and BDNF in rat hippocampus and prefrontal cortex

(2013) W. Zhou et al.   EUROPEAN PSYCHIATRY

Glucocorticoid actions on synapses, circuits, and behavior: Implications for the energetics of stress

(2013) Brent Myers et al.   FRONTIERS IN NEUROENDOCRINOLOGY

The Munc13 Proteins Differentially Regulate Readily Releasable Pool Dynamics and Calcium-Dependent Recovery at a Central Synapse

(2013) Z. Chen et al.   JOURNAL OF NEUROSCIENCE

Cortical Control of Affective Networks

(2013) S. Kumar et al.   JOURNAL OF NEUROSCIENCE

Hippocampal gene expression changes underlying stress sensitization and recovery

(2013) J D Gray et al.   MOLECULAR PSYCHIATRY

Stress-induced metaplasticity: From synapses to behavior

(2013) M.V. Schmidt et al.   NEUROSCIENCE

GPR158, an Orphan Member of G Protein-Coupled Receptor Family C: Glucocorticoid-Stimulated Expression and Novel Nuclear Role

(2013) Nitin Patel et al.   PLoS One

Monoamine neurocircuitry in depression and strategies for new treatments

(2013) Michel Hamon et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Glucocorticoid receptor signaling in health and disease

(2013) Mahita Kadmiel et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

G protein-linked signaling pathways in bipolar and major depressive disorders

(2013) Hiroaki Tomita et al.   Frontiers in Genetics

GPR179 Is Required for Depolarizing Bipolar Cell Function and Is Mutated in Autosomal-Recessive Complete Congenital Stationary Night Blindness

(2012) Neal S. Peachey et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Whole-Exome Sequencing Identifies Mutations in GPR179 Leading to Autosomal-Recessive Complete Congenital Stationary Night Blindness

(2012) Isabelle Audo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Identification of the Cortical Neurons that Mediate Antidepressant Responses

(2012) Eric F. Schmidt et al.   CELL

GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes

(2012) Cesare Orlandi et al.   JOURNAL OF CELL BIOLOGY

A prefrontal cortex–brainstem neuronal projection that controls response to behavioural challenge

(2012) Melissa R. Warden et al.   NATURE

Repeated Stress Causes Cognitive Impairment by Suppressing Glutamate Receptor Expression and Function in Prefrontal Cortex

(2012) Eunice Y. Yuen et al.   NEURON

G Protein–Coupled Receptor Deorphanizations

(2011) Olivier Civelli et al.   Annual Review of Pharmacology and Toxicology

pUNISHER: a high-level expression cassette for use with recombinant viral vectors for rapid and long term in vivo neuronal expression in the CNS

(2011) Monica S. Montesinos et al.   JOURNAL OF NEUROPHYSIOLOGY

Integrated behavioral z-scoring increases the sensitivity and reliability of behavioral phenotyping in mice: Relevance to emotionality and sex

(2011) Jean-Philippe Guilloux et al.   JOURNAL OF NEUROSCIENCE METHODS

NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses

(2011) Anita E. Autry et al.   NATURE

Chronic antidepressant treatments induce a time-dependent up-regulation of AMPA receptor subunit protein levels

(2011) Alessandro Barbon et al.   NEUROCHEMISTRY INTERNATIONAL

Resilient emotionality and molecular compensation in mice lacking the oligodendrocyte-specific gene Cnp1

(2011) N M Edgar et al.   Translational Psychiatry

Antidepressant Effect of Optogenetic Stimulation of the Medial Prefrontal Cortex

(2010) H. E. Covington et al.   JOURNAL OF NEUROSCIENCE

Local Presynaptic Activity Gates Homeostatic Changes in Presynaptic Function Driven by Dendritic BDNF Synthesis

(2010) Sonya K. Jakawich et al.   NEURON

Regulation of hippocampal H3 histone methylation by acute and chronic stress

(2009) R. G. Hunter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-lasting behavioral effects and recognition memory deficit induced by chronic mild stress in mice: effect of antidepressant treatment

(2008) N. Elizalde et al.   PSYCHOPHARMACOLOGY

The Antidepressant Fluoxetine Restores Plasticity in the Adult Visual Cortex

(2008) J. F. M. Vetencourt et al.   SCIENCE

Repeated stress alters dendritic spine morphology in the rat medial prefrontal cortex

(2007) Jason J. Radley et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test

(2007) Todd D. Gould et al.   NEUROPHARMACOLOGY