Social deficits in IRSp53 mutant mice improved by NMDAR and mGluR5 suppression

Attention Deficit Hyperactivity Disorder and N-methyl-D-aspartate (NMDA) Dysregulation

(2014) Jane Chang et al.   CURRENT PHARMACEUTICAL DESIGN

Are NMDA receptor antagonists beneficial in the treatment of schizophrenia?

(2014) Seong S. Shim et al.   JOURNAL OF PSYCHIATRIC RESEARCH

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality

(2014) Tzyy-Nan Huang et al.   NATURE NEUROSCIENCE

Neurobiology of autism gene products: towards pathogenesis and drug targets

(2014) Kristel T. E. Kleijer et al.   PSYCHOPHARMACOLOGY

Fragile X syndrome: From protein function to therapy

(2013) Claudia Bagni et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The Genetic Landscapes of Autism Spectrum Disorders

(2013) Guillaume Huguet et al.   Annual Review of Genomics and Human Genetics

BAIAP2 exhibits association to childhood ADHD especially predominantly inattentive subtype in Chinese Han subjects

(2013) Lu Liu et al.   Behavioral and Brain Functions

Postsynaptic distribution of IRSp53 in spiny excitatory and inhibitory neurons

(2013) Alain C. Burette et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Activity-dependent neuronal signalling and autism spectrum disorder

(2013) Daniel H. Ebert et al.   NATURE

Progress toward treatments for synaptic defects in autism

(2013) Richard Delorme et al.   NATURE MEDICINE

The translation of translational control by FMRP: therapeutic targets for FXS

(2013) Jennifer C Darnell et al.   NATURE NEUROSCIENCE

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

Functional Consequences of Mutations in Postsynaptic Scaffolding Proteins and Relevance to Psychiatric Disorders

(2012) Jonathan T. Ting et al.   Annual Review of Neuroscience

Disruption of Dentate Gyrus Blocks Effect of Visual Input on Spatial Firing of CA1 Neurons

(2012) J. W. Lee et al.   JOURNAL OF NEUROSCIENCE

Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

(2012) Hyejung Won et al.   NATURE

Deletion of Glutamate Delta-1 Receptor in Mouse Leads to Aberrant Emotional and Social Behaviors

(2012) Roopali Yadav et al.   PLoS One

Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders

(2012) Will Spooren et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Ultrastructure of Synapses in the Mammalian Brain

(2012) K. M. Harris et al.   Cold Spring Harbor Perspectives in Biology

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

(2012) H. Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

Absence of CNTNAP2 Leads to Epilepsy, Neuronal Migration Abnormalities, and Core Autism-Related Deficits

(2011) Olga Peñagarikano et al.   CELL

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

(2011) Dan Levy et al.   NEURON

Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses

(2011) Sarah R. Gilman et al.   NEURON

Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function

(2011) M. Etherton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rare Copy Number Variation Discovery and Cross-Disorder Comparisons Identify Risk Genes for ADHD

(2011) A. C. Lionel et al.   Science Translational Medicine

Motor and cognitive stereotypies in the BTBR T+tf/J mouse model of autism

(2010) B. L. Pearson et al.   GENES BRAIN AND BEHAVIOR

Association study of six candidate genes asymmetrically expressed in the two cerebral hemispheres suggests the involvement of BAIAP2 in autism

(2010) Claudio Toma et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders

(2010) Dan Ehninger et al.   TRENDS IN MOLECULAR MEDICINE

Case-Control Study of Six Genes Asymmetrically Expressed in the Two Cerebral Hemispheres: Association of BAIAP2 with Attention-Deficit/Hyperactivity Disorder

(2009) Marta Ribasés et al.   BIOLOGICAL PSYCHIATRY

The Insulin Receptor Substrate of 53 kDa (IRSp53) Limits Hippocampal Synaptic Plasticity

(2009) Corinna Sawallisch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhanced NMDA Receptor-Mediated Synaptic Transmission, Enhanced Long-Term Potentiation, and Impaired Learning and Memory in Mice Lacking IRSp53

(2009) M.-H. Kim et al.   JOURNAL OF NEUROSCIENCE

The Medial Prefrontal Cortex and Integration in Autism

(2009) Dorit Ben Shalom   NEUROSCIENTIST

Social approach and repetitive behavior in eleven inbred mouse strains

(2008) Sheryl S. Moy et al.   BEHAVIOURAL BRAIN RESEARCH

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy

(2008) Lorenzo A. Cingolani et al.   NATURE REVIEWS NEUROSCIENCE

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism

(2008) S. Jamain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions

(2008) Giorgio Scita et al.   TRENDS IN CELL BIOLOGY

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR