Revised roles of ISL1 in a hES cell-based model of human heart chamber specification

Generation and cardiac subtype-specific differentiation of PITX2-deficient human iPS cell lines for exploring familial atrial fibrillation

(2017) Maike Marczenke et al.   Stem Cell Research

Cardiac Subtype-Specific Modeling of Kv1.5 Ion Channel Deficiency Using Human Pluripotent Stem Cells

(2017) Maike Marczenke et al.   Frontiers in Physiology

Rigorous Phenotyping of Cardiac iPSC Preparations Requires Knowledge of Their Resting Potential(s)

(2016) Wayne R. Giles et al.   BIOPHYSICAL JOURNAL

Expandable Cardiovascular Progenitor Cells Reprogrammed from Fibroblasts

(2016) Yu Zhang et al.   Cell Stem Cell

Stepwise Clearance of Repressive Roadblocks Drives Cardiac Induction in Human ESCs

(2016) Jyoti Rao et al.   Cell Stem Cell

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

ISL1 and JMJD3 synergistically control cardiac differentiation of embryonic stem cells

(2016) Yang Wang et al.   NUCLEIC ACIDS RESEARCH

Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology

(2015) H. D. Devalla et al.   EMBO Molecular Medicine

Mechanisms of retinoic acid signalling and its roles in organ and limb development

(2015) Thomas J. Cunningham et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Universal Cardiac Induction of Human Pluripotent Stem Cells in Two and Three-Dimensional Formats: Implications for In Vitro Maturation

(2015) Miao Zhang et al.   STEM CELLS

Direct Nkx2-5 Transcriptional Repression of Isl1 Controls Cardiomyocyte Subtype Identity

(2015) Tatjana Dorn et al.   STEM CELLS

Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis

(2015) Laurent Dupays et al.   Cell Reports

Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1

(2015) Rosalie M. E. Meijer van Putten et al.   Frontiers in Physiology

Identification and Purification of Human Induced Pluripotent Stem Cell-Derived Atrial-Like Cardiomyocytes Based on Sarcolipin Expression

(2014) Rebecca Josowitz et al.   PLoS One

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

(2013) F. Ann Ran et al.   CELL

Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions

(2013) Nan Cao et al.   CELL RESEARCH

Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity

(2013) Esteban O Mazzoni et al.   NATURE NEUROSCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

A Temporal Chromatin Signature in Human Embryonic Stem Cells Identifies Regulators of Cardiac Development

(2012) Sharon L. Paige et al.   CELL

Dynamic and Coordinated Epigenetic Regulation of Developmental Transitions in the Cardiac Lineage

(2012) Joseph A. Wamstad et al.   CELL

The LIM Protein Ajuba Restricts the Second Heart Field Progenitor Pool by Regulating Isl1 Activity

(2012) Hagen R. Witzel et al.   DEVELOPMENTAL CELL

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Identifying ChIP-seq enrichment using MACS

(2012) Jianxing Feng et al.   Nature Protocols

Small Molecule-Assisted, Line-Independent Maintenance of Human Pluripotent Stem Cells in Defined Conditions

(2012) Stefan Frank et al.   PLoS One

Fibroblast growth factor 10 gene regulation in the second heart field by Tbx1, Nkx2-5, and Islet1 reveals a genetic switch for down-regulation in the myocardium

(2012) Y. Watanabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cozzarelli Prize Winner: Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling

(2012) X. Lian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induced pluripotent stem cell derived cardiomyocytes as models for cardiac arrhythmias

(2012) Maaike Hoekstra et al.   Frontiers in Physiology

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents

(2011) Junyi Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors

(2009) Alessandra Moretti et al.   FASEB JOURNAL

Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages

(2009) Lei Bu et al.   NATURE

A regulatory pathway involving Notch1/β-catenin/Isl1 determines cardiac progenitor cell fate.

(2009) Chulan Kwon et al.   NATURE CELL BIOLOGY

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

Retinoic Acid Synthesis and Signaling during Early Organogenesis

(2008) Gregg Duester   CELL

Identification of Cardiac-Specific Myosin Light Chain Kinase

(2008) Jason Y. Chan et al.   CIRCULATION RESEARCH

Retinoic acid controls heart anteroposterior patterning by down-regulatingIsl1 through theFgf8 pathway

(2008) Ioan Ovidiu Sirbu et al.   DEVELOPMENTAL DYNAMICS

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

(2008) Lei Yang et al.   NATURE

Retinoic acid deficiency alters second heart field formation

(2008) L. Ryckebusch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY