Dynein–Dynactin–NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble

Regulation of mitotic spindle assembly factor NuMA by Importin-β

(2017) Chih-Chia Chang et al.   JOURNAL OF CELL BIOLOGY

Molecular mechanism of dynein recruitment to kinetochores by the Rod–Zw10–Zwilch complex and Spindly

(2017) José B. Gama et al.   JOURNAL OF CELL BIOLOGY

Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP2

(2017) Elsa A. Tungadi et al.   JOURNAL OF CELL SCIENCE

NuMA recruits dynein activity to microtubule minus-ends at mitosis

(2017) Christina L Hueschen et al.   eLife

Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly

(2016) Yoana N. Dimitrova et al.   CELL

Dynein Clusters into Lipid Microdomains on Phagosomes to Drive Rapid Transport toward Lysosomes

(2016) Ashim Rai et al.   CELL

NuMA Phosphorylation by Aurora-A Orchestrates Spindle Orientation

(2016) Sara Gallini et al.   CURRENT BIOLOGY

Regulation of mitotic spindle orientation: an integrated view

(2016) Florencia di Pietro et al.   EMBO REPORTS

Rapid Protein Depletion in Human Cells by Auxin-Inducible Degron Tagging with Short Homology Donors

(2016) Toyoaki Natsume et al.   Cell Reports

NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures

(2016) Lindsey Seldin et al.   eLife

Direct Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin Clouds

(2015) Mijung Kwon et al.   DEVELOPMENTAL CELL

Mechanisms of daughter cell-size control during cell division

(2015) Tomomi Kiyomitsu   TRENDS IN CELL BIOLOGY

SiR–Hoechst is a far-red DNA stain for live-cell nanoscopy

(2015) Gražvydas Lukinavičius et al.   Nature Communications

The Dual Characteristics of Light-Induced Cryptochrome 2, Homo-oligomerization and Heterodimerization, for Optogenetic Manipulation in Mammalian Cells

(2015) Daphne L. Che et al.   ACS Synthetic Biology

NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane

(2014) S. Kotak et al.   EMBO JOURNAL

In vitroreconstitution of a highly processive recombinant human dynein complex

(2014) Max A Schlager et al.   EMBO JOURNAL

Autoinhibition and cooperative activation mechanisms of cytoplasmic dynein

(2014) Takayuki Torisawa et al.   NATURE CELL BIOLOGY

Fluorogenic probes for live-cell imaging of the cytoskeleton

(2014) Gražvydas Lukinavičius et al.   NATURE METHODS

Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins

(2014) Gurkan Guntas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes

(2014) R. J. McKenney et al.   SCIENCE

The Kinetochore

(2014) I. M. Cheeseman   Cold Spring Harbor Perspectives in Biology

Cortical Dynein and Asymmetric Membrane Elongation Coordinately Position the Spindle in Anaphase

(2013) Tomomi Kiyomitsu et al.   CELL

Oriented divisions, fate decisions

(2013) Scott E Williams et al.   CURRENT OPINION IN CELL BIOLOGY

Mechanisms of spindle positioning: cortical force generators in the limelight

(2013) Sachin Kotak et al.   CURRENT OPINION IN CELL BIOLOGY

Cell cycle–regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation

(2013) Zhen Zheng et al.   MOLECULAR BIOLOGY OF THE CELL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Cortical Dynein Controls Microtubule Dynamics to Generate Pulling Forces that Position Microtubule Asters

(2012) Liedewij Laan et al.   CELL

The Kinetochore-Bound Ska1 Complex Tracks Depolymerizing Microtubules and Binds to Curved Protofilaments

(2012) Jens C. Schmidt et al.   DEVELOPMENTAL CELL

Cortical dynein is critical for proper spindle positioning in human cells

(2012) Sachin Kotak et al.   JOURNAL OF CELL BIOLOGY

Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

(2012) Ari J. Firestone et al.   NATURE

Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation

(2012) Tomomi Kiyomitsu et al.   NATURE CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

The structure of purified kinetochores reveals multiple microtubule-attachment sites

(2012) Shane Gonen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ABL1 regulates spindle orientation in adherent cells and mammalian skin

(2012) Shigeru Matsumura et al.   Nature Communications

Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development

(2011) Xavier Morin et al.   DEVELOPMENTAL CELL

LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways

(2011) Jinwei Zhu et al.   MOLECULAR CELL

MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis

(2011) Catarina P. Samora et al.   NATURE CELL BIOLOGY

The Fz-Dsh Planar Cell Polarity Pathway Induces Oriented Cell Division via Mud/NuMA in Drosophila and Zebrafish

(2010) Marion Ségalen et al.   DEVELOPMENTAL CELL

Long astral microtubules uncouple mitotic spindles from the cytokinetic furrow

(2010) Kathleen E. Rankin et al.   JOURNAL OF CELL BIOLOGY

Inhibition of Protein 4.1 R and NuMA Interaction by Mutagenization of Their Binding-Sites Abrogates Nuclear Localization of 4.1 R

(2009) Subhendra N. Mattagajasingh et al.   CTS-Clinical and Translational Science

Requirements for NuMA in maintenance and establishment of mammalian spindle poles

(2009) Alain D. Silk et al.   JOURNAL OF CELL BIOLOGY

Determination of the Cleavage Plane in Early C. elegans Embryos

(2008) Matilde Galli et al.   Annual Review of Genetics

Fibrils Connect Microtubule Tips with Kinetochores: A Mechanism to Couple Tubulin Dynamics to Chromosome Motion

(2008) J. Richard McIntosh et al.   CELL

CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether

(2008) Yumi Kim et al.   JOURNAL OF CELL BIOLOGY

Mechanisms of asymmetric cell division: flies and worms pave the way

(2008) Pierre Gönczy   NATURE REVIEWS MOLECULAR CELL BIOLOGY