Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia

Utility of DNA methylation to assess placental health

(2018) Samantha L. Wilson et al.   PLACENTA

Mining DNA methylation alterations towards a classification of placental pathologies

(2017) Samantha L Wilson et al.   HUMAN MOLECULAR GENETICS

Dysregulated DNA Methyltransferase 3A Upregulates IGFBP5 to Suppress Trophoblast Cell Migration and Invasion in PreeclampsiaNovelty and Significance

(2017) Yuanhui Jia et al.   HYPERTENSION

A complex association between DNA methylation and gene expression in human placenta at first and third trimesters

(2017) Yen Ching Lim et al.   PLoS One

Decreased mRNA expression levels of DNA methyltransferases type 1 and 3A in systemic lupus erythematosus

(2017) Mariusz J. Nawrocki et al.   RHEUMATOLOGY INTERNATIONAL

Sexual epigenetic dimorphism in the human placenta: implications for susceptibility during the prenatal period

(2017) Elizabeth Martin et al.   Epigenomics

Unsupervised Placental Gene Expression Profiling Identifies Clinically Relevant Subclasses of Human PreeclampsiaNovelty and Significance

(2016) Katherine Leavey et al.   HYPERTENSION

Comprehensive analysis of DNA methylation and gene expression of placental tissue in preeclampsia patients

(2016) Jin Xuan et al.   HYPERTENSION IN PREGNANCY

Non-coding RNAs as drug targets

(2016) Masayuki Matsui et al.   NATURE REVIEWS DRUG DISCOVERY

Differential Expression of Extracellular Matrix and Adhesion Molecules in Fetal-Origin Amniotic Epithelial Cells of Preeclamptic Pregnancy

(2016) Myung-Sun Kim et al.   PLoS One

The aberrantly expressed miR-193b-3p contributes to preeclampsia through regulating transforming growth factor-β signaling

(2016) Xinyao Zhou et al.   Scientific Reports

Chronic inflammation of the placenta: definition, classification, pathogenesis, and clinical significance

(2015) Chong Jai Kim et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Changes in correlation between promoter methylation and gene expression in cancer

(2015) Matahi Moarii et al.   BMC GENOMICS

Human body epigenome maps reveal noncanonical DNA methylation variation

(2015) Matthew D. Schultz et al.   NATURE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

The Reactome pathway Knowledgebase

(2015) Antonio Fabregat et al.   NUCLEIC ACIDS RESEARCH

Characterization of whole-genome autosomal differences of DNA methylation between men and women

(2015) Paula Singmann et al.   Epigenetics & Chromatin

The Human Placental Methylome

(2015) W. P. Robinson et al.   Cold Spring Harbor Perspectives in Medicine

Large Scale Aggregate Microarray Analysis Reveals Three Distinct Molecular Subclasses of Human Preeclampsia

(2015) Katherine Leavey et al.   PLoS One

Overlapping DNA methylation profile between placentas with trisomy 16 and early-onset preeclampsia

(2014) J.D. Blair et al.   PLACENTA

Lipidomic Assessment of Plasma and Placenta of Women with Early-Onset Preeclampsia

(2014) Henri Augusto Korkes et al.   PLoS One

Meta-analysis of human methylomes reveals stably methylated sequences surrounding CpG islands associated with high gene expression

(2014) Rachel Edgar et al.   Epigenetics & Chromatin

Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy

(2014) Laura A. Magee et al.   Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health

ChAMP: 450k Chip Analysis Methylation Pipeline

(2013) Tiffany J. Morris et al.   BIOINFORMATICS

Hypoxia alters the epigenetic profile in cultured human placental trophoblasts

(2013) Ryan K.C. Yuen et al.   Epigenetics

Dynamic DNA methylation across diverse human cell lines and tissues

(2013) K. E. Varley et al.   GENOME RESEARCH

A leading role for the immune system in the pathophysiology of preeclampsia

(2013) Estibalitz Laresgoiti-Servitje   JOURNAL OF LEUKOCYTE BIOLOGY

Placental syndecan-1 and sulphated glycosaminoglycans are decreased in preeclampsia

(2013) Narinda Heyer-Chauhan et al.   JOURNAL OF PERINATAL MEDICINE

Widespread DNA hypomethylation at gene enhancer regions in placentas associated with early-onset pre-eclampsia

(2013) J. D. Blair et al.   MOLECULAR HUMAN REPRODUCTION

DNA methylation: roles in mammalian development

(2013) Zachary D. Smith et al.   NATURE REVIEWS GENETICS

Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array

(2013) Magda E Price et al.   Epigenetics & Chromatin

Levels of Key Enzymes of Methionine-Homocysteine Metabolism in Preeclampsia

(2013) Alejandra Pérez-Sepúlveda et al.   Biomed Research International

Differential placental methylation and expression of VEGF, FLT-1 and KDR genes in human term and preterm preeclampsia

(2013) Deepali P Sundrani et al.   Clinical Epigenetics

Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

(2013) Jessica Nordlund et al.   GENOME BIOLOGY

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

A comparison of feature selection and classification methods in DNA methylation studies using the Illumina Infinium platform

(2012) Joanna J Zhuang et al.   BMC BIOINFORMATICS

DNA Methylation Profiling Identifies Global Methylation Differences and Markers of Adrenocortical Tumors

(2012) Nesrin S. Rechache et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

DNA methylation profiling in the clinic: applications and challenges

(2012) Holger Heyn et al.   NATURE REVIEWS GENETICS

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

(2012) Lovisa E. Reinius et al.   PLoS One

Heterogeneity in White Blood Cells Has Potential to Confound DNA Methylation Measurements

(2012) Bjorn T. Adalsteinsson et al.   PLoS One

Factors underlying variable DNA methylation in a human community cohort

(2012) L. L. Lam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors

(2011) Boris Novakovic et al.   BMC GENOMICS

Epigenetics in Alternative Pre-mRNA Splicing

(2011) Reini F. Luco et al.   CELL

Preeclampsia leads to dysregulation of various signaling pathways in placenta

(2011) Jin Hee Kang et al.   JOURNAL OF HYPERTENSION

Lipid Rafts and Cytoskeletal Proteins in Placental Microvilli Membranes from Preeclamptic and IUGR Pregnancies

(2011) Gloria Riquelme et al.   JOURNAL OF MEMBRANE BIOLOGY

The Epigenetic promise for prostate cancer diagnosis

(2011) Leander Van Neste et al.   PROSTATE

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

(2010) Pan Du et al.   BMC BIOINFORMATICS

Evaluating DNA methylation and gene expression variability in the human term placenta

(2010) L. Avila et al.   PLACENTA

Targeting DNA methylation for epigenetic therapy

(2010) Xiaojing Yang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Epigenetic mechanisms and genome stability

(2010) Emily L. Putiri et al.   Clinical Epigenetics

Decreased DNA methyltransferase levels contribute to abnormal gene expression in “senescent” CD4+CD28− T cells

(2009) Ying Liu et al.   CLINICAL IMMUNOLOGY

Histone modifications at human enhancers reflect global cell-type-specific gene expression

(2009) Nathaniel D. Heintzman et al.   NATURE

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS