Mining DNA methylation alterations towards a classification of placental pathologies

An empirically driven data reduction method on the human 450K methylation array to remove tissue specific non-variable CpGs

(2017) Rachel D. Edgar et al.   Clinical Epigenetics

DNA methylation profiles in preeclampsia and healthy control placentas

(2016) Kristen R. Yeung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Unsupervised Placental Gene Expression Profiling Identifies Clinically Relevant Subclasses of Human PreeclampsiaNovelty and Significance

(2016) Katherine Leavey et al.   HYPERTENSION

Placental growth factor as a marker of fetal growth restriction caused by placental dysfunction

(2016) Samantha J. Benton et al.   PLACENTA

Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies

(2016) Emily Bartsch et al.   BMJ-British Medical Journal

Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies

(2016) Emily Bartsch et al.   BMJ-British Medical Journal

Genome-wide placental DNA methylation analysis of severely growth-discordant monochorionic twins reveals novel epigenetic targets for intrauterine growth restriction

(2016) Maian Roifman et al.   Clinical Epigenetics

Placental DNA methylation at term reflects maternal serum levels of INHA and FN1, but not PAPPA, early in pregnancy

(2015) Samantha L. Wilson et al.   BMC Medical Genetics

Morphological changes of placental syncytium and their implications for the pathogenesis of preeclampsia

(2015) Cynthia S. Roland et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pre-eclampsia has an adverse impact on maternal and fetal health

(2015) Saunders Lin et al.   Translational Research

Large Scale Aggregate Microarray Analysis Reveals Three Distinct Molecular Subclasses of Human Preeclampsia

(2015) Katherine Leavey et al.   PLoS One

Reference-free cell mixture adjustments in analysis of DNA methylation data

(2014) Eugene Andres Houseman et al.   BIOINFORMATICS

CXCL9 and CXCL10 Expression Are Critical for Control of Genital Herpes Simplex Virus Type 2 Infection through Mobilization of HSV-Specific CTL and NK Cells to the Nervous System

(2014) M. Thapa et al.   JOURNAL OF IMMUNOLOGY

Early Developmental Conditioning of Later Health and Disease: Physiology or Pathophysiology?

(2014) M. A. Hanson et al.   PHYSIOLOGICAL REVIEWS

Overlapping DNA methylation profile between placentas with trisomy 16 and early-onset preeclampsia

(2014) J.D. Blair et al.   PLACENTA

Different expression of placental pyruvate kinase in normal, preeclamptic and intrauterine growth restriction pregnancies

(2014) B.L. Bahr et al.   PLACENTA

Differential Methylation of Genes Associated with Cell Adhesion in Preeclamptic Placentas

(2014) Lauren Anton et al.   PLoS One

Comprehensive Analysis of Preeclampsia-Associated DNA Methylation in the Placenta

(2014) Tianjiao Chu et al.   PLoS One

Stratified randomization controls better for batch effects in 450K methylation analysis: a cautionary tale

(2014) Olive D. Buhule et al.   Frontiers in Genetics

Hypoxia alters the epigenetic profile in cultured human placental trophoblasts

(2013) Ryan K.C. Yuen et al.   Epigenetics

Dynamic DNA methylation across diverse human cell lines and tissues

(2013) K. E. Varley et al.   GENOME RESEARCH

If we know so much about preeclampsia, why haven’t we cured the disease?

(2013) James M. Roberts et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Widespread DNA hypomethylation at gene enhancer regions in placentas associated with early-onset pre-eclampsia

(2013) J. D. Blair et al.   MOLECULAR HUMAN REPRODUCTION

Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array

(2013) Magda E Price et al.   Epigenetics & Chromatin

Differential placental methylation and expression of VEGF, FLT-1 and KDR genes in human term and preterm preeclampsia

(2013) Deepali P Sundrani et al.   Clinical Epigenetics

DNA methylation arrays as surrogate measures of cell mixture distribution

(2012) Eugene Houseman et al.   BMC BIOINFORMATICS

Combined Screening for Preeclampsia and Small for Gestational Age at 11–13 Weeks

(2012) Leona C.Y. Poon et al.   FETAL DIAGNOSIS AND THERAPY

Low Placental Growth Factor Across Pregnancy Identifies a Subset of Women With Preterm Preeclampsia

(2012) Robert W. Powers et al.   HYPERTENSION

Can placental growth factor in maternal circulation identify fetuses with placental intrauterine growth restriction?

(2011) Samantha J. Benton et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Infant growth restriction is associated with distinct patterns of DNA methylation in human placentas

(2011) Carolyn E. Banister et al.   Epigenetics

DNA methylation ofIGF2,GNASAS,INSIGFandLEPand being born small for gestational age

(2011) Elmar W. Tobi et al.   Epigenetics

High density DNA methylation array with single CpG site resolution

(2011) Marina Bibikova et al.   GENOMICS

Screening for preeclampsia using first-trimester serum markers and uterine artery Doppler in nulliparous women

(2010) François Audibert et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Pre-eclampsia

(2010) Eric AP Steegers et al.   LANCET

Gene function analysis in complex data sets using ErmineJ

(2010) Jesse Gillis et al.   Nature Protocols

Evaluating DNA methylation and gene expression variability in the human term placenta

(2010) L. Avila et al.   PLACENTA

Assessing the role of placental trisomy in preeclampsia and intrauterine growth restriction

(2009) Wendy P. Robinson et al.   PRENATAL DIAGNOSIS

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

The placenta in pre-eclampsia and intrauterine growth restriction

(2008) D J Roberts et al.   JOURNAL OF CLINICAL PATHOLOGY

The Human Intermediate Filament Database: comprehensive information on a gene family involved in many human diseases

(2007) Ildiko Szeverenyi et al.   HUMAN MUTATION