Specific or not specific recruitment of DNMTs for DNA methylation, an epigenetic dilemma

ZEB1 induces ER-α promoter hypermethylation and confers antiestrogen resistance in breast cancer

(2017) Jianbo Zhang et al.   Cell Death & Disease

Epigenetic response to environmental stress: Assembly of BRG1–G9a/GLP–DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts

(2016) Pei Han et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Specific Inhibition of DNMT3A/ISGF3γ Interaction Increases the Temozolomide Efficiency to Reduce Tumor Growth

(2016) Mathilde Cheray et al.   Theranostics

DNMT3L interacts with transcription factors to target DNMT3L/DNMT3B to specific DNA sequences: Role of the DNMT3L/DNMT3B/p65-NFκB complex in the (de-)methylation of TRAF1

(2014) Romain Pacaud et al.   BIOCHIMIE

Specific inhibition of DNMT1/CFP1 reduces cancer phenotypes and enhances chemotherapy effectiveness

(2014) Mathilde Cheray et al.   Epigenomics

Analysis of DNA methylation change induced by Dnmt3b in mouse hepatocytes

(2013) Mayumi Takahashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9

(2013) Xiaoli Liu et al.   Nature Communications

Specific inhibition of one DNMT1-including complex influences tumor initiation and progression

(2013) Mathilde Cheray et al.   Clinical Epigenetics

Methylation of RASSF1A gene promoter is regulated by p53 and DAXX

(2012) Hailong Zhang et al.   FASEB JOURNAL

Mutant p53 binds to estrogen receptor negative promoter via DNMT1 and HDAC1 in MDA-MB-468 breast cancer cells

(2012) Rita Arabsolghar et al.   MOLECULAR BIOLOGY REPORTS

DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes

(2012) Eriko G. Clements et al.   NUCLEIC ACIDS RESEARCH

Kinetics of DNA methylation inheritance by the Dnmt1-including complexes during the cell cycle

(2012) Eric Hervouet et al.   Cell Division

Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells

(2012) Shikhar Sharma et al.   Epigenetics & Chromatin

In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases

(2012) Julia Arand et al.   PLoS Genetics

PKC isoforms interact with and phosphorylate DNMT1

(2011) Geneviève Lavoie et al.   BMC BIOLOGY

Proximity ligation in situ assay for monitoring the global DNA methylation in cells

(2011) Eric Hervouet et al.   BMC BIOTECHNOLOGY

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

(2011) Max Felle et al.   NUCLEIC ACIDS RESEARCH

The Oncoprotein EVI1 and the DNA Methyltransferase Dnmt3 Co-Operate in Binding and De Novo Methylation of Target DNA

(2011) Vitalyi Senyuk et al.   PLoS One

Differential Recruitment of Methyl CpG-Binding Domain Factors and DNA Methyltransferases by the Orphan Receptor Germ Cell Nuclear Factor Initiates the Repression and Silencing of Oct4

(2011) Peili Gu et al.   STEM CELLS

MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a

(2011) Yanqi Chang et al.   Nature Communications

The DNA-binding activity of mouse DNA methyltransferase 1 is regulated by phosphorylation with casein kinase 1δ/ε

(2010) Yasunori Sugiyama et al.   BIOCHEMICAL JOURNAL

DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development

(2010) Tao Fan et al.   Epigenetics

Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation

(2010) Eric Hervouet et al.   Epigenetics

Targeting of EZH2 to a defined genomic site is sufficient for recruitment of Dnmt3a but not de novo DNA methylation

(2010) Margaret Rush et al.   Epigenetics

De NovoDNA Methyltransferase DNMT3b Interacts with NEDD8-modified Proteins

(2010) Meir Shamay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Dnmt3a PWWP Domain Reads Histone 3 Lysine 36 Trimethylation and Guides DNA Methylation

(2010) Arunkumar Dhayalan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1

(2010) W. Pan et al.   JOURNAL OF IMMUNOLOGY

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

(2010) Jian Feng et al.   NATURE NEUROSCIENCE

A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability

(2010) Pierre-Olivier Estève et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail

(2010) Yingying Zhang et al.   NUCLEIC ACIDS RESEARCH

Targeting of De Novo DNA Methylation Throughout the Oct-4 Gene Regulatory Region in Differentiating Embryonic Stem Cells

(2010) Rodoniki Athanasiadou et al.   PLoS One

Disruption of Dnmt1/PCNA/UHRF1 Interactions Promotes Tumorigenesis from Human and Mice Glial Cells

(2010) Eric Hervouet et al.   PLoS One

Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues

(2010) G. Velasco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of the DNA methyltransferases expression on the methylation status of apoptosis-associated genes in glioblastoma multiforme

(2010) E Hervouet et al.   Cell Death & Disease

SUMOylation enhances DNA methyltransferase 1 activity

(2009) Bongyong Lee et al.   BIOCHEMICAL JOURNAL

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1

(2009) R. Garzon et al.   BLOOD

DNMT1 and DNMT3B Modulate Distinct Polycomb-Mediated Histone Modifications in Colon Cancer

(2009) B. Jin et al.   CANCER RESEARCH

Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX–DNMT3–DNMT3L domain

(2009) Junji Otani et al.   EMBO REPORTS

Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells

(2009) Daniela Meilinger et al.   EMBO REPORTS

Dmap1 plays an essential role in the maintenance of genome integrity through the DNA repair process

(2009) Masamitsu Negishi et al.   GENES TO CELLS

DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions

(2009) Suhasni Gopalakrishnan et al.   HUMAN MOLECULAR GENETICS

Dimerization of DNA methyltransferase 1 is mediated by its regulatory domain

(2009) Karin Fellinger et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

CG dinucleotide periodicities recognized by the Dnmt3a–Dnmt3L complex are distinctive at retroelements and imprinted domains

(2009) Jacob L. Glass et al.   MAMMALIAN GENOME

Selective Anchoring of DNA Methyltransferases 3A and 3B to Nucleosomes Containing Methylated DNA

(2009) S. Jeong et al.   MOLECULAR AND CELLULAR BIOLOGY

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing

(2009) Quan Zhao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The multi-domain protein Np95 connects DNA methylation and histone modification

(2009) Andrea Rottach et al.   NUCLEIC ACIDS RESEARCH

DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis

(2009) G Foltz et al.   ONCOGENE

The N-terminus of histone H3 is required for de novo DNA methylation in chromatin

(2009) Jia-Lei Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

(2009) P.-O. Esteve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lsh Participates in DNA Methylation and Silencing of Stem Cell Genes

(2009) Sichuan Xi et al.   STEM CELLS

CXXC Domain of Human DNMT1 Is Essential for Enzymatic Activity

(2008) Mihika Pradhan et al.   BIOCHEMISTRY

CFP1 Interacts with DNMT1 Independently of Association with the Setd1 Histone H3K4 Methyltransferase Complexes

(2008) Jill Sergesketter Butler et al.   DNA AND CELL BIOLOGY

Daxx represses RelB target promoters via DNA methyltransferase recruitment and DNA hypermethylation

(2008) L. A. Puto et al.   GENES & DEVELOPMENT

Structure and Hemimethylated CpG Binding of the SRA Domain from Human UHRF1

(2008) Chengmin Qian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G9a and HP1 Couple Histone and DNA Methylation to TNFα Transcription Silencing during Endotoxin Tolerance

(2008) Mohamed El Gazzar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bmi1 regulates memory CD4 T cell survival via repression of theNoxagene

(2008) Masakatsu Yamashita et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epigenetic modification induced by hepatitis B virus X protein via interaction with de novo DNA methyltransferase DNMT3A

(2008) Da-Li Zheng et al.   JOURNAL OF HEPATOLOGY

Characterization of Dnmt3b:Thymine-DNA Glycosylase Interaction and Stimulation of Thymine Glycosylase-Mediated Repair by DNA Methyltransferase(s) and RNA

(2008) Michael J. Boland et al.   JOURNAL OF MOLECULAR BIOLOGY

Cyclical DNA methylation of a transcriptionally active promoter

(2008) Raphaël Métivier et al.   NATURE

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix

(2008) Hideharu Hashimoto et al.   NATURE

Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism

(2008) Kyohei Arita et al.   NATURE

Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1

(2008) George V. Avvakumov et al.   NATURE

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

(2008) Jing Wang et al.   NATURE GENETICS

De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

(2008) Silvina Epsztejn-Litman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells

(2008) Jong Kyong Kim et al.   NUCLEIC ACIDS RESEARCH

Cooperation between EZH2, NSPc1-mediated histone H2A ubiquitination and Dnmt1 in HOX gene silencing

(2008) Xudong Wu et al.   NUCLEIC ACIDS RESEARCH

Double Strand Breaks Can Initiate Gene Silencing and SIRT1-Dependent Onset of DNA Methylation in an Exogenous Promoter CpG Island

(2008) Heather M. O'Hagan et al.   PLoS Genetics

DNMT1 interacts with the developmental transcriptional repressor HESX1

(2007) Ezat Sajedi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH