Article
Infectious Diseases
Josef Chudacek, Petr Spicka, Milan Kolar, Martin Stasek, Stefan Kolcun, Dusan Klos, Kristyna Hricova, Patrik Mlynarcik, Vendula Pudova, Olga Klementova, Rostislav Horacek
Summary: This study extends the existing knowledge of hospital-acquired pneumonia (HAP) complicating secondary peritonitis by providing detailed microbiological characteristics, including the identification of isolated bacterial pathogens and their potential sources. The study emphasizes the importance of initial antibiotic therapy effective against enterobacteria, ESBL and AmpC β-lactamases producing strains, Pseudomonas aeruginosa, and Enterococcus faecalis in patients with secondary peritonitis complicated by HAP. Monitoring the respiratory tract bacterial microflora in these patients is also highlighted as important.
Article
Medicine, General & Internal
Yingying Jiang, Chunlei Fan, Yan Dang, Wenmin Zhao, Lingna Lv, Jinli Lou, Lei Li, Huiguo Ding
Summary: This study aimed to determine the characteristics, prognosis, and risk factors of cirrhotic patients with spontaneous fungal peritonitis (SFP) and fungiascites, as well as to develop a predictive model for early differentiation of SFP/fungiascites from spontaneous bacterial peritonitis (SBP).
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Silvia Wuerstle, Alexander Hapfelmeier, Siranush Karapetyan, Fabian Studen, Andriana Isaakidou, Tillman Schneider, Roland M. Schmid, Stefan von Delius, Felix Gundling, Rainer Burgkart, Andreas Obermeier, Ulrich Mayr, Marc Ringelhan, Sebastian Rasch, Tobias Lahmer, Fabian Geisler, Paul E. Turner, Benjamin K. Chan, Christoph D. Spinner, Jochen Schneider
Summary: Ascitic fluid infection is a serious complication of liver cirrhosis, and it is crucial to distinguish between spontaneous bacterial peritonitis (SBP) and secondary peritonitis in these patients due to different treatment approaches. This study analyzed 532 SBP episodes and 37 secondary peritonitis episodes to identify key differentiation criteria. Microbiological characteristics, severity of illness, and clinicopathological parameters were identified as the most important predictors to distinguish between SBP and secondary peritonitis. A point-score model with ten discriminatory features was established, and two cut-off scores were defined to divide patients into low-risk and high-risk groups for secondary peritonitis based on a sensitivity of 95% to rule out or rule in SBP episodes. Overall, the discrimination between secondary peritonitis and SBP remains challenging, but the findings of this study may help clinicians with the crucial differentiation.
Article
Veterinary Sciences
Rachel Marwood, Kathryn Fleming, Aurore Veronique Masson, Hannah Gilmour, Frederike Schiborra, Thomas W. Maddox
Summary: This study aimed to determine the accuracy of abdominal radiography for diagnosing pneumoperitoneum in animals and investigate the impact of observer experience. The results showed variability in accuracy among veterinarians with different levels of experience. Further research is needed to validate these findings in other populations of animals with pneumoperitoneum.
Article
Veterinary Sciences
Giovanni Pavone, Barbara Castellucci, Silvia Pavone, Valentina Stefanetti, Chiara Vitolo, Sara Mangiaterra
Summary: This case report describes a Bobtail dog with biliary peritonitis due to gastric perforation, possibly induced by the administration of nonsteroidal anti-inflammatory drugs (NSAIDs). The dog underwent elective surgery and was referred for medical management due to inappetence, mental depression, and gastric vomits with traces of blood. Clinical diagnostic tests confirmed the presence of biliary peritonitis. The dog was euthanized due to worsening clinical conditions. Macroscopic examination revealed free brownish abdominal effusion and a perforating ulcer in the stomach pylorus region.
VETERINARY SCIENCES
(2023)
Article
Veterinary Sciences
Fatima Zahra Laabouri, Chelsea Folmar, Vicente Avila Reyes, Erin Beasley, Clare Ryan, Corrie Brown
Summary: This case study presents a perforating ulcer in a 3-day-old Brahman heifer, which resulted from a congenital narrowing of the pylorus and proximal duodenum. The condition caused significant abomasal distention, leakage, peritonitis, and sepsis.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Review
Gastroenterology & Hepatology
Roman Liebe, Irene Esposito, Hans H. Bock, Stephan vom Dahl, Jan Stindt, Ulrich Baumann, Tom Luedde, Verena Keitel
Summary: The term NAFLD was originally used to describe hepatic fat deposition in association with the metabolic syndrome. Secondary causes of fatty liver disease should be considered during diagnosis and treatment to halt disease progression, while genetic variants may play a role in the development and progression of liver diseases.
JOURNAL OF HEPATOLOGY
(2021)
Article
Immunology
Hao-Xin Wu, Wei Hou, Wei Zhang, Zheng Wang, Shan Guo, De-Xi Chen, Zhen Li, Feili Wei, Zhongjie Hu
Summary: BactDNA detection can enhance the efficiency of diagnosis for spontaneous bacterial peritonitis and play a role in the clinical assessment of antibiotic treatment.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Surgery
Nicolas Siembida, Charles Sabbagh, Tami Chal, Marion Demouron, Davide Rossi, Jeanne Dembinski, Jean-Marc Regimbeau
Summary: This study retrospectively evaluated the need for abdominal drainage after surgery for lower gastrointestinal tract peritonitis and found that drainage may not be necessary. Further research is needed to establish guidelines for postoperative drainage.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Article
Anesthesiology
Hugues Georges, Adrien Krings, Patrick Devos, Pierre-Yves Delannoy, Nicolas Boussekey, Damien Thellier, Vanessa Jean-Michel, Thomas Caulier, Olivier Leroy
Summary: In this study, inappropriate IAT was not associated with a worse prognosis in ICU patients with secondary peritonitis, and carbapenems were found to be overused.
MINERVA ANESTESIOLOGICA
(2022)
Article
Infectious Diseases
Liang Xu, Shaotang Ye, Yulin Ding, Yuqing Xiao, Congwen Yao, Zhen Wang, Siqi Cai, Jiajun Ou, Jianwei Mao, Xuerui Hu, Song Cheng, Jingyu Wang, Gang Lu, Shoujun Li
Summary: A new rapid and highly sensitive method for clinical diagnosis of FIPV infection was explored in this study, based on the FIPV BS8 N protein monoclonal antibody. A combination method of indirect immunofluorescence assay (IFA) and nested reverse transcription polymerase chain reaction (RT-nPCR) was used to examine FIP-suspected clinical samples, and the results were 100% consistent with immunohistochemistry (IHC), indicating the potential of this method for rapid and accurate diagnosis of FIPV infection within 24 hours.
TRANSBOUNDARY AND EMERGING DISEASES
(2023)
Article
Surgery
Guido Fallani, Raffaele Lombardi, Michele Masetti, Mario Chisari, Nicola Zanini, Gaetano M. Cattaneo, Mauro Filosa, Federico Zanzi, Enrico Guerra, Stefano Bonilauri, Luca Di Donato, Gianluca Garulli, Andrea Lucchi, Michele Grassia, Giampaolo Ugolini, Francesco Pasini, Gaetano Vetrone, Claudia Benini, Simone Nicosia, Elio Jovine
Summary: This study examined the impact of the COVID-19 pandemic on the outcomes of patients undergoing surgery for peritonitis, revealing that patients in the COVID period group were more likely to present late to emergency departments and had a higher rate of postoperative complications.
UPDATES IN SURGERY
(2021)
Review
Pediatrics
Jiaxi Huang, Chaojun Du, Wenbo Zhang, Yaping Mi, Yaping Shan, Huifeng Zhang, Qiqi Shi, Gang Chen
Summary: Unguarded severe tricuspid regurgitation caused by rupture of papillary muscle or chordae tendineae is a rare but fatal condition in neonates. Limited experience exists in the management of these patients. This case report highlights the importance of echocardiography in diagnosing and prompt surgical intervention in neonates with tricuspid regurgitation secondary to rupture of chordae tendineae.
FRONTIERS IN PEDIATRICS
(2023)
Review
Medicine, General & Internal
Tomoyuki Hioki, Mayumi Komine, Mamitaro Ohtsuki
Summary: Psoriatic arthritis is a chronic inflammatory disorder that can cause deformities and joint damage, impacting quality of life. Early diagnosis and intervention are important to prevent permanent disability, but the clinical features overlap with other diseases, making early detection and intervention challenging.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Plant Sciences
Irfan Bashir Ganie, Zishan Ahmad, Anwar Shahzad, Alexandra Zaushintsena, Olga Neverova, Svetlana Ivanova, Adla Wasi, Sabaha Tahseen
Summary: Centella asiatica, also known as Gotu kola, is a medicinal plant with a wide range of active metabolites. However, limited cultivation and overexploitation have led to severe depletion of its resources. This review provides up-to-date information on biotechnological tools for in vitro propagation, secondary metabolite production, and biosynthetic mechanism of Centella asiatica.
