Implementation of Fully Integrated Continuous Antibody Processing: Effects on Productivity and COGm

Single pass diafiltration integrated into a fully continuous mAb purification process

(2018) Joanna Rucker-Pezzini et al.   BIOTECHNOLOGY AND BIOENGINEERING

Continuous desalting of refolded protein solution improves capturing in ion exchange chromatography: A seamless process

(2017) Nicole Walch et al.   Biotechnology Journal

Adapting viral safety assurance strategies to continuous processing of biological products

(2016) Sarah A. Johnson et al.   BIOTECHNOLOGY AND BIOENGINEERING

Continuous precipitation of process related impurities from clarified cell culture supernatant using a novel coiled flow inversion reactor (CFIR)

(2016) Nikhil Kateja et al.   Biotechnology Journal

Continuous counter-current chromatography for capture and polishing steps in biopharmaceutical production

(2016) Fabian Steinebach et al.   Biotechnology Journal

Life-cycle and cost of goods assessment of fed-batch and perfusion-based manufacturing processes for mAbs

(2016) Phumthep Bunnak et al.   BIOTECHNOLOGY PROGRESS

Continuous viral inactivation at low pH value in antibody manufacturing

(2016) Stephan Klutz et al.   CHEMICAL ENGINEERING AND PROCESSING

Continuous precipitation of process related impurities from clarified cell culture supernatant using a novel coiled flow inversion reactor (CFIR)

(2016) Nikhil Kateja et al.   Biotechnology Journal

Continuous counter-current chromatography for capture and polishing steps in biopharmaceutical production

(2016) Fabian Steinebach et al.   Biotechnology Journal

Continuous and semi-continuous cell culture for production of blood clotting factors

(2015) Sunil G. Desai   JOURNAL OF BIOTECHNOLOGY

Purification of monoclonal antibodies from clarified cell culture fluid using Protein A capture continuous countercurrent tangential chromatography

(2015) Amit K. Dutta et al.   JOURNAL OF BIOTECHNOLOGY

A new, integrated, continuous purification process template for monoclonal antibodies: Process modeling and cost of goods studies

(2015) Alex Xenopoulos   JOURNAL OF BIOTECHNOLOGY

The business impact of an integrated continuous biomanufacturing platform for recombinant protein production

(2015) Jason Walther et al.   JOURNAL OF BIOTECHNOLOGY

Developing the biofacility of the future based on continuous processing and single-use technology

(2015) Stephan Klutz et al.   JOURNAL OF BIOTECHNOLOGY

Large-scale monoclonal antibody purification by continuous chromatography, from process design to scale-up

(2015) Valérie Girard et al.   JOURNAL OF BIOTECHNOLOGY

White Paper on Continuous Bioprocessing May 20–21 2014 Continuous Manufacturing Symposium

(2015) Konstantin B. Konstantinov et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Perspectives on integrated continuous bioprocessing—opportunities and challenges

(2015) Andrew L Zydney   Current Opinion in Chemical Engineering

Continuous bioprocessing: The real thing this time?

(2014) Suzanne S Farid et al.   mAbs

Design of high productivity sequential multi-column chromatography for antibody capture

(2013) Candy K.S. Ng et al.   FOOD AND BIOPRODUCTS PROCESSING

Integrated continuous production of recombinant therapeutic proteins

(2012) Veena Warikoo et al.   BIOTECHNOLOGY AND BIOENGINEERING

The need for innovation in biomanufacturing

(2012) Uwe Gottschalk et al.   NATURE BIOTECHNOLOGY

An improved manufacturing process for Xyntha/ReFacto AF

(2009) B. KELLEY et al.   HAEMOPHILIA