Staphylococcus aureus Toxins and Their Molecular Activity in Infectious Diseases

Staphylococcus aureus pore-forming toxins: The interface of pathogen and host complexity

(2017) E. Sachiko Seilie et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Improved Protection in a Rabbit Model of Community-Associated Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia upon Neutralization of Leukocidins in Addition to Alpha-Hemolysin

(2016) Binh An Diep et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bacterial Sphingomyelinases and Phospholipases as Virulence Factors

(2016) Marietta Flores-Díaz et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Staphylococcus aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes

(2015) András N. Spaan et al.   Cell Host & Microbe

Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

(2015) Steven Y. C. Tong et al.   CLINICAL MICROBIOLOGY REVIEWS

Role of Phenol-Soluble Modulins in Formation of Staphylococcus aureus Biofilms in Synovial Fluid

(2015) Sana S. Dastgheyb et al.   INFECTION AND IMMUNITY

Differential Interaction of the Staphylococcal Toxins Panton–Valentine Leukocidin and γ-Hemolysin CB with Human C5a Receptors

(2015) András N. Spaan et al.   JOURNAL OF IMMUNOLOGY

Molecular characteristics and virulence factors in methicillin-susceptible, resistant, and heterogeneous vancomycin-intermediate Staphylococcus aureus from central-southern China

(2015) Cailin Liu et al.   JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION

Antibiotic Discovery: Combatting Bacterial Resistance in Cells and in Biofilm Communities

(2015) Anahit Penesyan et al.   MOLECULES

Staphylococcus aureus Biofilms Induce Macrophage Dysfunction Through Leukocidin AB and Alpha-Toxin

(2015) Tyler D. Scherr et al.   mBio

Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular

(2015) Jason H. Melehani et al.   PLoS Pathogens

Polysaccharide intercellular adhesin in biofilm: structural and regulatory aspects

(2015) Carla Renata Arciola et al.   Frontiers in Cellular and Infection Microbiology

Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of theStaphylococcus aureusBi-component Toxin LukGH

(2014) Adriana Badarau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Five birds, one stone: Neutralization of α-hemolysin and 4 bi-component leukocidins ofStaphylococcus aureuswith a single human monoclonal antibody

(2014) Harald Rouha et al.   mAbs

The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors

(2014) András N. Spaan et al.   Nature Communications

Three-Dimensional Human Skin Models to Understand Staphylococcus aureus Skin Colonization and Infection

(2014) Lauren Popov et al.   Frontiers in Immunology

A Serologic Correlate of Protective Immunity Against Community-Onset Staphylococcus aureus Infection

(2013) Stephanie A. Fritz et al.   CLINICAL INFECTIOUS DISEASES

The effects of Staphylococcus aureus leukotoxins on the host: cell lysis and beyond

(2013) Pauline Yoong et al.   CURRENT OPINION IN MICROBIOLOGY

Staphylococcus aureus toxins

(2013) Michael Otto   CURRENT OPINION IN MICROBIOLOGY

Staphylococcus aureus Elaborates Leukocidin AB To Mediate Escape from within Human Neutrophils

(2013) Ashley L. DuMont et al.   INFECTION AND IMMUNITY

Identification of a Crucial Residue Required for Staphylococcus aureus LukAB Cytotoxicity and Receptor Recognition

(2013) Ashley L. DuMont et al.   INFECTION AND IMMUNITY

Staphylococcus aureus toxins – Their functions and genetics

(2013) Dorothee Grumann et al.   INFECTION GENETICS AND EVOLUTION

Beta-Hemolysin Promotes Skin Colonization by Staphylococcus aureus

(2013) Y. Katayama et al.   JOURNAL OF BACTERIOLOGY

Phenol-soluble modulins and staphylococcal infection

(2013) Andreas Peschel et al.   NATURE REVIEWS MICROBIOLOGY

Staphylococcus aureus α-Toxin: Nearly a Century of Intrigue

(2013) Bryan Berube et al.   Toxins

Phospholipid Scramblase 1 Mediates Type I Interferon-Induced Protection against Staphylococcal α-Toxin

(2012) Miroslaw Lizak et al.   Cell Host & Microbe

Structural Model of the Pre-pore Ring-like Structure of Panton-Valentine Leukocidin: Providing Dimensionality to Biophysical and Mutational Data

(2012) M. Javad Aman et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Lower Antibody Levels to Staphylococcus aureus Exotoxins Are Associated With Sepsis in Hospitalized Adults With Invasive S. aureus Infections

(2012) R. P. Adhikari et al.   JOURNAL OF INFECTIOUS DISEASES

ADAM10 Mediates Vascular Injury Induced by Staphylococcus aureus α-Hemolysin

(2012) Michael E. Powers et al.   JOURNAL OF INFECTIOUS DISEASES

CCR5 is a receptor for Staphylococcus aureus leukotoxin ED

(2012) Francis Alonzo III et al.   NATURE

Alpha-Toxin Induces Programmed Cell Death of Human T cells, B cells, and Monocytes during USA300 Infection

(2012) Tyler K. Nygaard et al.   PLoS One

How Staphylococcus aureus biofilms develop their characteristic structure

(2012) S. Periasamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Infecting Strains and Superantigen-Neutralizing Antibodies inStaphylococcus aureusBacteremia

(2011) Dorothee Grumann et al.   Clinical and Vaccine Immunology

Staphylococcus aureus leucocidin ED contributes to systemic infection by targeting neutrophils and promoting bacterial growth in vivo

(2011) Francis Alonzo III et al.   MOLECULAR MICROBIOLOGY

A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice

(2011) Ichiro Inoshima et al.   NATURE MEDICINE

Should we stay or should we go: mechanisms and ecological consequences for biofilm dispersal

(2011) Diane McDougald et al.   NATURE REVIEWS MICROBIOLOGY

Crystal structure of the octameric pore of staphylococcal  -hemolysin reveals the  -barrel pore formation mechanism by two components

(2011) K. Yamashita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular differentiation of historic phage-type 80/81 and contemporary epidemic Staphylococcus aureus

(2011) F. R. DeLeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinctive patterns in the human antibody response to Staphylococcus aureus bacteremia in carriers and non-carriers

(2011) Julia Kolata et al.   PROTEOMICS

Staphylococcus aureusbiofilms

(2011) Nathan K. Archer et al.   Virulence

A Novel Core Genome-Encoded Superantigen Contributes to Lethality of Community-Associated MRSA Necrotizing Pneumonia

(2011) Gillian J. Wilson et al.   PLoS Pathogens

Mucosal tissue polyclonal IgE is functional in response to allergen and SEB

(2010) N. Zhang et al.   ALLERGY

Basis of Virulence in Community-Associated Methicillin-ResistantStaphylococcus aureus

(2010) Michael Otto   Annual Review of Microbiology

Reduced Vancomycin Susceptibility in Staphylococcus aureus, Including Vancomycin-Intermediate and Heterogeneous Vancomycin-Intermediate Strains: Resistance Mechanisms, Laboratory Detection, and Clinical Implications

(2010) B. P. Howden et al.   CLINICAL MICROBIOLOGY REVIEWS

Neutrophil responses to staphylococcal pathogens and commensals via the formyl peptide receptor 2 relates to phenol-soluble modulin release and virulence

(2010) Maren Rautenberg et al.   FASEB JOURNAL

Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma

(2010) Claus Bachert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Virulence Genes and Genotypic Associations in Nasal Carriage, Community-Associated Methicillin-Susceptible and Methicillin-Resistant USA400 Staphylococcus aureus Isolates

(2010) S. K. Shukla et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis

(2010) Ashley L. DuMont et al.   MOLECULAR MICROBIOLOGY

Staphylococcus aureus Pathogenesis

(2010) Allison H. Bartlett et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Identification of a Novel Staphylococcus aureus Two-Component Leukotoxin Using Cell Surface Proteomics

(2010) Christy L. Ventura et al.   PLoS One

Beta toxin catalyzes formation of nucleoprotein matrix in staphylococcal biofilms

(2010) M. J. Huseby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exfoliative Toxins of Staphylococcus aureus

(2010) Michal Bukowski et al.   Toxins

Staphylococcus aureus Beta-Toxin Induces Lung Injury through Syndecan-1

(2009) Atsuko Hayashida et al.   AMERICAN JOURNAL OF PATHOLOGY

Prevention and Treatment of Staphylococcus aureus Pneumonia with a  -Cyclodextrin Derivative

(2009) B. E. Ragle et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Intrinsic asthma: not so different from allergic asthma but driven by superantigens?

(2009) P. J. Barnes   CLINICAL AND EXPERIMENTAL ALLERGY

Role of staphylococcal superantigens in upper airway disease

(2009) Claus Bachert et al.   Current Opinion in Allergy and Clinical Immunology

Anti-Alpha-Hemolysin Monoclonal Antibodies Mediate Protection against Staphylococcus aureus Pneumonia

(2009) B. E. Ragle et al.   INFECTION AND IMMUNITY

Diversity of Prophages in Dominant Staphylococcus aureus Clonal Lineages

(2009) C. Goerke et al.   JOURNAL OF BACTERIOLOGY

Quorum Sensing in Staphylococci

(2008) Richard P. Novick et al.   Annual Review of Genetics

Inhibition of Endothelial Interleukin-8 Production and Neutrophil Transmigration by Staphylococcus aureus Beta-Hemolysin

(2008) A. Tajima et al.   INFECTION AND IMMUNITY

Identification and Characterization of Two Novel Staphylococcal Enterotoxins, Types S and T

(2008) H. K. Ono et al.   INFECTION AND IMMUNITY

Changes in the Prevalence of Nasal Colonization withStaphylococcus aureusin the United States, 2001–2004

(2008) Rachel J. Gorwitz et al.   JOURNAL OF INFECTIOUS DISEASES

ADAM10-Mediated E-Cadherin Release Is Regulated by Proinflammatory Cytokines and Modulates Keratinocyte Cohesion in Eczematous Dermatitis

(2008) Thorsten Maretzky et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The ADAM metalloproteinases

(2008) D EDWARDS et al.   MOLECULAR ASPECTS OF MEDICINE

agr-Mediated Dispersal of Staphylococcus aureus Biofilms

(2008) Blaise R. Boles et al.   PLoS Pathogens

Staphylococcal exfoliative toxins: “Molecular scissors” of bacteria that attack the cutaneous defense barrier in mammals

(2007) Koji Nishifuji et al.   JOURNAL OF DERMATOLOGICAL SCIENCE