Heterogeneity in pneumolysin expression governs the fate of Streptococcus pneumoniae during blood-brain barrier trafficking
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Title
Heterogeneity in pneumolysin expression governs the fate of Streptococcus pneumoniae during blood-brain barrier trafficking
Authors
Keywords
Blood, Analysis of variance, Intracellular pathogens, Autophagic cell death, Cytosol, Flow cytometry, Endothelium, Mutant strains
Journal
PLoS Pathogens
Volume 14, Issue 7, Pages e1007168
Publisher
Public Library of Science (PLoS)
Online
2018-07-17
DOI
10.1371/journal.ppat.1007168
References
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Note: Only part of the references are listed.- Molecular mechanisms of Streptococcus pneumoniae -targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked ubiquitination
- (2018) Michinaga Ogawa et al. CELLULAR MICROBIOLOGY
- pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion
- (2017) Federico Iovino et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TIGR4 strain causes more severe disease than WU2 strain in a mouse model of Streptococcus pneumoniae meningitis: a common pathogenic role for interferon-γ
- (2017) Belinda Yau et al. MICROBES AND INFECTION
- Measuring kinetic drivers of pneumolysin pore structure
- (2016) Robert J. C. Gilbert et al. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
- Pneumococcal meningitis is promoted by single cocci expressing pilus adhesin RrgA
- (2016) Federico Iovino et al. JOURNAL OF CLINICAL INVESTIGATION
- Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses
- (2015) Roi Avraham et al. CELL
- Rational Manipulation of mRNA Folding Free Energy Allows Rheostat Control of Pneumolysin Production by Streptococcus pneumoniae
- (2015) Fábio E. Amaral et al. PLoS One
- V-ATPase and osmotic imbalances activate endolysosomal LC3 lipidation
- (2014) Oliver Florey et al. Autophagy
- Platelet Endothelial Cell Adhesion Molecule-1, a Putative Receptor for the Adhesion of Streptococcus pneumoniae to the Vascular Endothelium of the Blood-Brain Barrier
- (2014) Federico Iovino et al. INFECTION AND IMMUNITY
- Bright Fluorescent Streptococcus pneumoniae for Live-Cell Imaging of Host-Pathogen Interactions
- (2014) Morten Kjos et al. JOURNAL OF BACTERIOLOGY
- Bacteria–autophagy interplay: a battle for survival
- (2014) Ju Huang et al. NATURE REVIEWS MICROBIOLOGY
- Streptococcus pneumoniae Interacts with pIgR Expressed by the Brain Microvascular Endothelium but Does Not Co-Localize with PAF Receptor
- (2014) Federico Iovino et al. PLoS One
- The Proteasome-Ubiquitin System Is Required for Efficient Killing of Intracellular Streptococcus pneumoniae by Brain Endothelial Cells
- (2014) F. Iovino et al. mBio
- Incomplete pneumolysin oligomers form membrane pores
- (2014) A. F.- P. Sonnen et al. Open Biology
- Streptococcus pyogenes Escapes from Autophagy
- (2013) Ichiro Nakagawa Cell Host & Microbe
- Interactions between Mytilus galloprovincialis hemocytes and the bivalve pathogens Vibrio aestuarianus 01/032 and Vibrio splendidus LGP32
- (2013) T. Balbi et al. FISH & SHELLFISH IMMUNOLOGY
- Clinical Implications of Pneumococcal Serotypes: Invasive Disease Potential, Clinical Presentations, and Antibiotic Resistance
- (2013) Joon Young Song et al. JOURNAL OF KOREAN MEDICAL SCIENCE
- Mechanisms of the vasorelaxing effects of CORM-3, a water-soluble carbon monoxide-releasing molecule: interactions with eNOS
- (2013) Ali Alshehri et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Streptococcus pneumoniae Invades Endothelial Host Cells via Multiple Pathways and Is Killed in a Lysosome Dependent Manner
- (2013) Henrik Gradstedt et al. PLoS One
- Interactions between Blood-Borne Streptococcus pneumoniae and the Blood-Brain Barrier Preceding Meningitis
- (2013) Federico Iovino et al. PLoS One
- Contribution of phenotypic heterogeneity to adaptive antibiotic resistance
- (2013) M. A. Sanchez-Romero et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Pneumococcus: Epidemiology, Microbiology, and Pathogenesis
- (2013) B. Henriques-Normark et al. Cold Spring Harbor Perspectives in Medicine
- Concepts and Mechanisms: Crossing Host Barriers
- (2013) K. S. Doran et al. Cold Spring Harbor Perspectives in Medicine
- An Initial Event in the Insect Innate Immune Response: Structural and Biological Studies of Interactions between β-1,3-Glucan and the N-Terminal Domain of β-1,3-Glucan Recognition Protein
- (2012) Huaien Dai et al. BIOCHEMISTRY
- Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion
- (2012) Teresa L. M. Thurston et al. NATURE
- Functional effects of SDF-1α on a CD44+ CXCR4+ squamous cell carcinoma cell line as a model for interactions in the cancer stem cell niche
- (2012) ANNE FABER et al. ONCOLOGY REPORTS
- Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation
- (2012) E. F. Castillo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pneumolysin with Low Hemolytic Activity Confers an Early Growth Advantage to Streptococcus pneumoniae in the Blood
- (2011) Richard M. Harvey et al. INFECTION AND IMMUNITY
- Epidemiology of community-acquired pneumonia in children of Latin America and the Caribbean: a systematic review and meta-analysis
- (2011) Angela Gentile et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Changes in Capsular Serotype Alter the Surface Exposure of Pneumococcal Adhesins and Impact Virulence
- (2011) Carlos J. Sanchez et al. PLoS One
- Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease
- (2010) Jason W. Rosch et al. JOURNAL OF CLINICAL INVESTIGATION
- The encapsulated strain TIGR4 of Streptococcus pneumoniae is phagocytosed but is resistant to intracellular killing by mouse microglia
- (2010) Samuele Peppoloni et al. MICROBES AND INFECTION
- Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models
- (2009) Carlos J. Orihuela et al. JOURNAL OF CLINICAL INVESTIGATION
- The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion
- (2009) Satoshi Uchiyama et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Pneumolysin generates multiple conductance pores in the membrane of nucleated cells
- (2008) Rana G. El-Rachkidy et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Pneumolysin: A Double-Edged Sword During the Host-Pathogen Interaction
- (2008) Helen Marriott et al. CURRENT MOLECULAR MEDICINE
- Shuttle expression plasmids for genetic studies in Streptococcus mutans
- (2008) I. Biswas et al. MICROBIOLOGY-SGM
- Self-destructive cooperation mediated by phenotypic noise
- (2008) Martin Ackermann et al. NATURE
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