Vaccine-induced antibodies to herpes simplex virus glycoprotein D epitopes involved in virus entry and cell-to-cell spread correlate with protection against genital disease in guinea pigs

Prophylactic Herpes Simplex Virus 2 (HSV-2) Vaccines Adjuvanted with Stable Emulsion and Toll-Like Receptor 9 Agonist Induce a Robust HSV-2-Specific Cell-Mediated Immune Response, Protect against Symptomatic Disease, and Reduce the Latent Viral Reservoir

(2017) Michael T. Hensel et al.   JOURNAL OF VIROLOGY

Global sensing of the antigenic structure of herpes simplex virus gD using high-throughput array-based SPR imaging

(2017) Tina M. Cairns et al.   PLoS Pathogens

An HSV-2 Trivalent Vaccine Is Immunogenic in Rhesus Macaques and Highly Efficacious in Guinea Pigs

(2017) Sita Awasthi et al.   PLoS Pathogens

First estimates of the global and regional incidence of neonatal herpes infection

(2017) Katharine J Looker et al.   Lancet Global Health

Nasal Immunization Confers High Avidity Neutralizing Antibody Response and Immunity to Primary and Recurrent Genital Herpes in Guinea Pigs

(2016) Josefine Persson et al.   Frontiers in Immunology

A Herpes Simplex Virus 2 (HSV-2) gD Mutant Impaired for Neural Tropism Is Superior to an HSV-2 gD Subunit Vaccine To Protect Animals from Challenge with HSV-2

(2015) Kening Wang et al.   JOURNAL OF VIROLOGY

Herpes simplex type 2 virus deleted in glycoprotein D protects against vaginal, skin and neural disease

(2015) Christopher Petro et al.   eLife

Global Estimates of Prevalent and Incident Herpes Simplex Virus Type 2 Infections in 2012

(2015) Katharine J. Looker et al.   PLoS One

Better Neutralization of Herpes Simplex Virus Type 1 (HSV-1) Than HSV-2 by Antibody From Recipients of GlaxoSmithKline HSV-2 Glycoprotein D2 Subunit Vaccine

(2014) Sita Awasthi et al.   JOURNAL OF INFECTIOUS DISEASES

Blocking Herpes Simplex Virus 2 Glycoprotein E Immune Evasion as an Approach To Enhance Efficacy of a Trivalent Subunit Antigen Vaccine for Genital Herpes

(2014) S. Awasthi et al.   JOURNAL OF VIROLOGY

Dissection of the Antibody Response against Herpes Simplex Virus Glycoproteins in Naturally Infected Humans

(2014) T. M. Cairns et al.   JOURNAL OF VIROLOGY

Topical Herpes Simplex Virus 2 (HSV-2) Vaccination with Human Papillomavirus Vectors Expressing gB/gD Ectodomains Induces Genital-Tissue-Resident Memory CD8+T Cells and Reduces Genital Disease and Viral Shedding after HSV-2 Challenge

(2014) Nicolas Çuburu et al.   JOURNAL OF VIROLOGY

Correlate of Immune Protection Against HSV-1 Genital Disease in Vaccinated Women

(2013) R. B. Belshe et al.   JOURNAL OF INFECTIOUS DISEASES

An Adjuvanted Herpes Simplex Virus 2 Subunit Vaccine Elicits a T Cell Response in Mice and Is an Effective Therapeutic Vaccine in Guinea Pigs

(2013) M. Skoberne et al.   JOURNAL OF VIROLOGY

Properties of mouse and human IgG receptors and their contribution to disease models

(2012) P. Bruhns   BLOOD

Efficacy Results of a Trial of a Herpes Simplex Vaccine

(2012) Robert B. Belshe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Herpes Virus Fusion and Entry: A Story with Many Characters

(2012) Roselyn J. Eisenberg et al.   Viruses-Basel

Single and Combination Herpes Simplex Virus Type 2 Glycoprotein Vaccines Adjuvanted with CpG Oligodeoxynucleotides or Monophosphoryl Lipid A Exhibit Differential Immunity That Is Not Correlated to Protection in Animal Models

(2011) Tansi Khodai et al.   Clinical and Vaccine Immunology

Genital Shedding of Herpes Simplex Virus Among Symptomatic and Asymptomatic Persons With HSV-2 Infection

(2011) Elizabeth Tronstein   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Herpes Simplex Virus 1 IgG Fc Receptor Blocks Antibody-Mediated Complement Activation and Antibody-Dependent Cellular Cytotoxicity In Vivo

(2011) J. M. Lubinski et al.   JOURNAL OF VIROLOGY

Immunization with Herpes Simplex Virus 2 (HSV-2) Genes plus Inactivated HSV-2 Is Highly Protective against Acute and Recurrent HSV-2 Disease

(2011) C. S. Morello et al.   JOURNAL OF VIROLOGY

Antibody-Induced Conformational Changes in Herpes Simplex Virus Glycoprotein gD Reveal New Targets for Virus Neutralization

(2011) E. Lazear et al.   JOURNAL OF VIROLOGY

Immunization with a Vaccine Combining Herpes Simplex Virus 2 (HSV-2) Glycoprotein C (gC) and gD Subunits Improves the Protection of Dorsal Root Ganglia in Mice and Reduces the Frequency of Recurrent Vaginal Shedding of HSV-2 DNA in Guinea Pigs Compared to Immunization with gD Alone

(2011) S. Awasthi et al.   JOURNAL OF VIROLOGY

Cascade of Events Governing Cell-Cell Fusion Induced by Herpes Simplex Virus Glycoproteins gD, gH/gL, and gB

(2010) D. Atanasiu et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Type 1 Glycoprotein E Mediates Retrograde Spread from Epithelial Cells to Neurites

(2009) H. M. McGraw et al.   JOURNAL OF VIROLOGY

The adjuvant CLDC increases protection of a herpes simplex type 2 glycoprotein D vaccine in guinea pigs

(2009) David I. Bernstein et al.   VACCINE

Antibody-mediated protection against genital herpes simplex virus type 2 disease in mice by Fc gamma receptor-dependent and -independent mechanisms

(2007) Chin-Fun Chu et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY