Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein

Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides

(2018) Hyung S. Oh et al.   PLoS Pathogens

The RNA-Binding Site of Poliovirus 3C Protein Doubles as a Phosphoinositide-Binding Domain

(2017) Djoshkun Shengjuler et al.   STRUCTURE

Escaping Host Factor PI4KB Inhibition: Enterovirus Genomic RNA Replication in the Absence of Replication Organelles

(2017) Charlotte E. Melia et al.   Cell Reports

Type III phosphatidylinositol 4 kinases: structure, function, regulation, signalling and involvement in disease

(2016) G. L. Dornan et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Entangled in a membranous web: ER and lipid droplet reorganization during hepatitis C virus infection

(2016) Nathan L Meyers et al.   CURRENT OPINION IN CELL BIOLOGY

PtdIns(4,5)P2signaling regulates ATG14 and autophagy

(2016) Xiaojun Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Positive-strand RNA viruses stimulate host phosphatidylcholine synthesis at viral replication sites

(2016) Jiantao Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsically disordered region of influenza A NP regulates viral genome packaging via interactions with viral RNA and host PI(4,5)P 2

(2016) Michinori Kakisaka et al.   VIROLOGY

The Ebola Virus matrix protein, VP40, requires phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) for extensive oligomerization at the plasma membrane and viral egress

(2016) Kristen A. Johnson et al.   Scientific Reports

Phosphatidylserine Vesicles Enable Efficient En Bloc Transmission of Enteroviruses

(2015) Ying-Han Chen et al.   CELL

Phosphatidylinositol 4-kinases: Function, structure, and inhibition

(2015) Evzen Boura et al.   EXPERIMENTAL CELL RESEARCH

Phosphatidylinositol 4,5-Bisphosphate Is an HCV NS5A Ligand and Mediates Replication of the Viral Genome

(2015) Nam-Joon Cho et al.   GASTROENTEROLOGY

Emerging roles of PtdIns(4,5)P2 - beyond the plasma membrane

(2015) X. Tan et al.   JOURNAL OF CELL SCIENCE

Viral precursor protein P3 and its processed products perform discrete and essential functions in the poliovirus RNA replication complex

(2015) Allyn Spear et al.   VIROLOGY

Daclatasvir inhibits hepatitis C virus NS5A motility and hyper-accumulation of phosphoinositides

(2015) Vineela Chukkapalli et al.   VIROLOGY

Conformational Ensemble of the Poliovirus 3CD Precursor Observed by MD Simulations and Confirmed by SAXS: A Strategy to Expand the Viral Proteome?

(2015) Ibrahim Moustafa et al.   Viruses-Basel

Innate Immunity and Immune Evasion by Enterovirus 71

(2015) Prabuddha Pathinayake et al.   Viruses-Basel

Mechanism of Poliovirus Resistance to Host Phosphatidylinositol-4 Kinase III β Inhibitor

(2015) Minetaro Arita   ACS Infectious Diseases

Flaviviridae Replication Organelles: Oh, What a Tangled Web We Weave

(2015) David Paul et al.   Annual Review of Virology

NS5A Inhibitors Impair NS5A–Phosphatidylinositol 4-Kinase IIIα Complex Formation and Cause a Decrease of Phosphatidylinositol 4-Phosphate and Cholesterol Levels in Hepatitis C Virus-Associated Membranes

(2014) V. Reghellin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Potential subversion of autophagosomal pathway by picornaviruses

(2014) Matthew P. Taylor et al.   Autophagy

Induction and suppression of innate antiviral responses by picornaviruses

(2014) Qian Feng et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Dengue Virus- and Hepatitis C Virus-Induced Replication and Assembly Compartments: the Enemy Inside--Caught in the Web

(2014) L. Chatel-Chaix et al.   JOURNAL OF VIROLOGY

GBF1- and ACBD3-Independent Recruitment of PI4KIIIβ to Replication Sites by Rhinovirus 3A Proteins

(2014) Cristina M. Dorobantu et al.   JOURNAL OF VIROLOGY

Nonlytic viral spread enhanced by autophagy components

(2014) S. W. Bird et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of Unique Poliovirus RNA Replication Organelles

(2014) A. L. Richards et al.   mBio

The interaction between human enteroviruses and type I IFN signaling pathway

(2013) Jing Lu et al.   CRITICAL REVIEWS IN MICROBIOLOGY

How Positive-Strand RNA Viruses Benefit from Autophagosome Maturation

(2013) A. L. Richards et al.   JOURNAL OF VIROLOGY

Recruitment of PI4KIII  to Coxsackievirus B3 Replication Organelles Is Independent of ACBD3, GBF1, and Arf1

(2013) C. M. Dorobantu et al.   JOURNAL OF VIROLOGY

Phosphoinositides: Tiny Lipids With Giant Impact on Cell Regulation

(2013) Tamas Balla   PHYSIOLOGICAL REVIEWS

The Lipid Kinase Phosphatidylinositol-4 Kinase III Alpha Regulates the Phosphorylation Status of Hepatitis C Virus NS5A

(2013) Simon Reiss et al.   PLoS Pathogens

Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication

(2012) Hilde M van der Schaar et al.   CELL RESEARCH

The 3A Protein from Multiple Picornaviruses Utilizes the Golgi Adaptor Protein ACBD3 To Recruit PI4KIII 

(2012) A. L. Greninger et al.   JOURNAL OF VIROLOGY

ARF1 and GBF1 Generate a PI4P-Enriched Environment Supportive of Hepatitis C Virus Replication

(2012) Leiliang Zhang et al.   PLoS One

Phosphatidylinositol 4-kinases: hostages harnessed to build panviral replication platforms

(2012) Nihal Altan-Bonnet et al.   TRENDS IN BIOCHEMICAL SCIENCES

Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity

(2012) Annalisa Bianco et al.   PLoS Pathogens

Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS5A Is Essential for Integrity of the Membranous Replication Compartment

(2011) Simon Reiss et al.   Cell Host & Microbe

ACBD3-mediated recruitment of PI4KB to picornavirus RNA replication sites

(2011) Jun Sasaki et al.   EMBO JOURNAL

Hepatitis C Virus Stimulates the Phosphatidylinositol 4-Kinase III Alpha-Dependent Phosphatidylinositol 4-Phosphate Production That Is Essential for Its Replication

(2011) K. L. Berger et al.   JOURNAL OF VIROLOGY

Complex Dynamic Development of Poliovirus Membranous Replication Complexes

(2011) G. A. Belov et al.   JOURNAL OF VIROLOGY

Picornavirus Subversion of the Autophagy Pathway

(2011) Kathryn A. Klein et al.   Viruses-Basel

Organelle-Like Membrane Compartmentalization of Positive-Strand RNA Virus Replication Factories

(2010) Johan A. den Boon et al.   Annual Review of Microbiology

Viral Reorganization of the Secretory Pathway Generates Distinct Organelles for RNA Replication

(2010) Nai-Yun Hsu et al.   CELL

Cytoplasmic Viral Replication Complexes

(2010) Johan A. den Boon et al.   Cell Host & Microbe

Expanding knowledge of P3 proteins in the poliovirus lifecycle

(2010) Craig E Cameron et al.   Future Microbiology

Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4Pand PtdIns(4,5)P2

(2009) Gerald R. V. Hammond et al.   BIOCHEMICAL JOURNAL

A structural and functional perspective of alphavirus replication and assembly

(2009) Joyce Jose et al.   Future Microbiology

PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions

(2009) I. van den Bout et al.   JOURNAL OF CELL SCIENCE

Insight into Poliovirus Genome Replication and Encapsidation Obtained from Studies of 3B-3C Cleavage Site Mutants

(2009) H. S. Oh et al.   JOURNAL OF VIROLOGY

Golgicide A reveals essential roles for GBF1 in Golgi assembly and function

(2009) José B Sáenz et al.   Nature Chemical Biology

Picornavirus Genome Replication

(2008) Harsh B. Pathak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY