Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+ transporting subunit Alpha 1 and prohibitin as host-cell factors involved in the life cycle of mammarenaviruses

MOV10 Provides Antiviral Activity against RNA Viruses by Enhancing RIG-I–MAVS-Independent IFN Induction

(2016) Rolando A. Cuevas et al.   JOURNAL OF IMMUNOLOGY

Host Protein Moloney Leukemia Virus 10 (MOV10) Acts as a Restriction Factor of Influenza A Virus by Inhibiting the Nuclear Import of the Viral Nucleoprotein

(2016) Junsong Zhang et al.   JOURNAL OF VIROLOGY

IRAV ( FLJ11286 ), an Interferon-Stimulated Gene with Antiviral Activity against Dengue Virus, Interacts with MOV10

(2016) Corey A. Balinsky et al.   JOURNAL OF VIROLOGY

Suppression of Adenovirus Replication by Cardiotonic Steroids

(2016) Filomena Grosso et al.   JOURNAL OF VIROLOGY

Rocaglates convert DEAD-box protein eIF4A into a sequence-selective translational repressor

(2016) Shintaro Iwasaki et al.   NATURE

Antagonism of the Sodium-Potassium ATPase Impairs Chikungunya Virus Infection

(2016) Alison W. Ashbrook et al.   mBio

Specialized Functional Diversity and Interactions of the Na,K-ATPase

(2016) Vladimir V. Matchkov et al.   Frontiers in Physiology

Identification and Mechanism of Action of a Novel Small-Molecule Inhibitor of Arenavirus Multiplication

(2015) Nhi Ngo et al.   JOURNAL OF VIROLOGY

ATP1A1-Mediated Src Signaling Inhibits Coronavirus Entry into Host Cells

(2015) Christine Burkard et al.   JOURNAL OF VIROLOGY

Single Nucleoprotein Residue Modulates Arenavirus Replication Complex Formation

(2015) Kristeene A. Knopp et al.   mBio

A Novel Class of Small Molecule Compounds that Inhibit Hepatitis C Virus Infection by Targeting the Prohibitin-CRaf Pathway

(2015) Shufeng Liu et al.   EBioMedicine

Elucidation of the Ebola Virus VP24 Cellular Interactome and Disruption of Virus Biology through Targeted Inhibition of Host-Cell Protein Function

(2014) Isabel García-Dorival et al.   JOURNAL OF PROTEOME RESEARCH

The chaperonin CCTα is required for efficient transcription and replication of rabies virus

(2014) Jinyang Zhang et al.   MICROBIOLOGY AND IMMUNOLOGY

Rocaglamide, silvestrol and structurally related bioactive compounds from Aglaia species

(2014) Li Pan et al.   NATURAL PRODUCT REPORTS

The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints

(2013) Jennifer Neumann et al.   INTERNATIONAL JOURNAL OF CANCER

Identification of Critical Amino Acids within the Nucleoprotein of Tacaribe Virus Important for Anti-interferon Activity

(2013) Brooke Harmon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression

(2013) Xue Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular Chaperonin CCT  Contributes to Rabies Virus Replication during Infection

(2013) J. Zhang et al.   JOURNAL OF VIROLOGY

Digoxin Suppresses HIV-1 Replication by Altering Viral RNA Processing

(2013) Raymond W. Wong et al.   PLoS Pathogens

Natural compounds inhibiting the replication of Porcine reproductive and respiratory syndrome virus

(2012) Anbu K. Karuppannan et al.   ANTIVIRAL RESEARCH

Identification of prohibitin as a Chikungunya virus receptor protein

(2012) Phitchayapak Wintachai et al.   JOURNAL OF MEDICAL VIROLOGY

Identification of Human Host Proteins Contributing to H5N1 Influenza Virus Propagation by Membrane Proteomics

(2012) Cheng Liu et al.   JOURNAL OF PROTEOME RESEARCH

The PI3K/Akt Pathway Contributes to Arenavirus Budding

(2012) Shuzo Urata et al.   JOURNAL OF VIROLOGY

Arenavirus Nucleoproteins Prevent Activation of Nuclear Factor Kappa B

(2012) W. W. S. I. Rodrigo et al.   JOURNAL OF VIROLOGY

Arenavirus Nucleoprotein Targets Interferon Regulatory Factor-Activating Kinase IKK 

(2012) C. Pythoud et al.   JOURNAL OF VIROLOGY

Arenavirus Infection Induces Discrete Cytosolic Structures for RNA Replication

(2012) N. L. Baird et al.   JOURNAL OF VIROLOGY

Structural Basis for the dsRNA Specificity of the Lassa Virus NP Exonuclease

(2012) Kathryn M. Hastie et al.   PLoS One

Endogenous MOV10 inhibits the retrotransposition of endogenous retroelements but not the replication of exogenous retroviruses

(2012) Shetal Arjan-Odedra et al.   Retrovirology

Identification of Molecular Determinants from Moloney Leukemia Virus 10 Homolog (MOV10) Protein for Virion Packaging and Anti-HIV-1 Activity

(2011) Aierken Abudu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple Functional Domains and Complexes of the Two Nonstructural Proteins of Human Respiratory Syncytial Virus Contribute to Interferon Suppression and Cellular Location

(2011) S. Swedan et al.   JOURNAL OF VIROLOGY

The C-Terminal Region of Lymphocytic Choriomeningitis Virus Nucleoprotein Contains Distinct and Segregable Functional Domains Involved in NP-Z Interaction and Counteraction of the Type I Interferon Response

(2011) E. Ortiz-Riano et al.   JOURNAL OF VIROLOGY

Ribavirin Can Be Mutagenic for Arenaviruses

(2011) H. Moreno et al.   JOURNAL OF VIROLOGY

Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression

(2011) K. M. Hastie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Moloney Leukemia Virus 10 (MOV10) Protein Inhibits Retrovirus Replication

(2010) Xiaojun Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Use of Single-Cycle Infectious Lymphocytic Choriomeningitis Virus To Study Hemorrhagic Fever Arenaviruses

(2010) W. W. S. I. Rodrigo et al.   JOURNAL OF VIROLOGY

Rescue from Cloned cDNAs and In Vivo Characterization of Recombinant Pathogenic Romero and Live-Attenuated Candid #1 Strains of Junin Virus, the Causative Agent of Argentine Hemorrhagic Fever Disease

(2010) S. F. Emonet et al.   JOURNAL OF VIROLOGY

P Body-Associated Protein Mov10 Inhibits HIV-1 Replication at Multiple Stages

(2010) R. Burdick et al.   JOURNAL OF VIROLOGY

Association of the Influenza Virus RNA Polymerase Subunit PB2 with the Host Chaperonin CCT

(2010) T. Fislova et al.   JOURNAL OF VIROLOGY

Cap binding and immune evasion revealed by Lassa nucleoprotein structure

(2010) Xiaoxuan Qi et al.   NATURE

Perturbation of the P-Body Component Mov10 Inhibits HIV-1 Infectivity

(2010) Vyacheslav Furtak et al.   PLoS One

Identification and characterization of prohibitin as a receptor protein mediating DENV-2 entry into insect cells

(2010) Atichat Kuadkitkan et al.   VIROLOGY

Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein

(2010) Yasushi Inoue et al.   VIROLOGY

Pilot study of huachansu in patients with hepatocellular carcinoma, nonsmall-cell lung cancer, or pancreatic cancer

(2009) Zhiqiang Meng et al.   CANCER

Respiratory Syncytial Virus Nonstructural Proteins Decrease Levels of Multiple Members of the Cellular Interferon Pathways

(2009) S. Swedan et al.   JOURNAL OF VIROLOGY

Identification of Amino Acid Residues Critical for the Anti-Interferon Activity of the Nucleoprotein of the Prototypic Arenavirus Lymphocytic Choriomeningitis Virus

(2009) L. Martinez-Sobrido et al.   JOURNAL OF VIROLOGY

Genetic Detection and Characterization of Lujo Virus, a New Hemorrhagic Fever–Associated Arenavirus from Southern Africa

(2009) Thomas Briese et al.   PLoS Pathogens

Anti-HSV activity of digitoxin and its possible mechanisms

(2008) Chun-Ting Su et al.   ANTIVIRAL RESEARCH

Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies

(2008) Alice Y Yam et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Treatment of Argentine hemorrhagic fever

(2007) Delia A. Enria et al.   ANTIVIRAL RESEARCH

New opportunities for field research on the pathogenesis and treatment of Lassa fever

(2007) Sheik Humarr Khan et al.   ANTIVIRAL RESEARCH