Ebselen alleviates testicular pathology in mice with Zika virus infection and prevents its sexual transmission

Frequent Zika Virus Sexual Transmission and Prolonged Viral RNA Shedding in an Immunodeficient Mouse Model

(2017) Nisha K. Duggal et al.   Cell Reports

Zika Virus Causes Testis Damage and Leads to Male Infertility in Mice

(2016) Wenqiang Ma et al.   CELL

Vaginal Exposure to Zika Virus during Pregnancy Leads to Fetal Brain Infection

(2016) Laura J. Yockey et al.   CELL

A Mouse Model of Zika Virus Pathogenesis

(2016) Helen M. Lazear et al.   Cell Host & Microbe

Zika Virus

(2016) Didier Musso et al.   CLINICAL MICROBIOLOGY REVIEWS

Persistent detection of Zika virus RNA in semen for six months after symptom onset in a traveller returning from Haiti to Italy, February 2016

(2016) Emanuele Nicastri et al.   Eurosurveillance

Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication

(2016) Shahzada Khan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection

(2016) Hyemin Kim et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Zika virus: high infectious viral load in semen, a new sexually transmitted pathogen?

(2016) Jean Michel Mansuy et al.   LANCET INFECTIOUS DISEASES

Zika virus infection damages the testes in mice

(2016) Jennifer Govero et al.   NATURE

Evidence of Sexual Transmission of Zika Virus

(2016) Eric D’Ortenzio et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika Virus

(2016) Lyle R. Petersen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Zika virus was transmitted by sexual contact in Texas, health officials report

(2016) Michael McCarthy   BMJ-British Medical Journal

A Mouse Model of Zika Virus Sexual Transmission and Vaginal Viral Replication

(2016) William Weihao Tang et al.   Cell Reports

How Relevant Is Sexual Transmission of Zika Virus?

(2016) Christian L. Althaus et al.   PLOS MEDICINE

Zika virus was transmitted by sexual contact in Texas, health officials report

(2016) Michael McCarthy   BMJ-British Medical Journal

Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility

(2015) Irina Ingold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Repurposing ebselen for treatment of multidrug-resistant staphylococcal infections

(2015) Shankar Thangamani et al.   Scientific Reports

Seminal fluid and reproduction: much more than previously thought

(2014) John J. Bromfield   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Characterizing and Diminishing Autofluorescence in Formalin-fixed Paraffin-embedded Human Respiratory Tissue

(2014) A. Sally Davis et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Ebselen, a promising antioxidant drug: mechanisms of action and targets of biological pathways

(2014) Gajendra Kumar Azad et al.   MOLECULAR BIOLOGY REPORTS

Effect of Oxidative Stress on Male Reproduction

(2014) Ashok Agarwal et al.   World Journal of Mens Health

Protective effect of ebselen on experimental testicular torsion and detorsion injury

(2013) M. M. Rifaioglu et al.   ANDROLOGIA

Reactive Oxygen Species in Inflammation and Tissue Injury

(2013) Manish Mittal et al.   ANTIOXIDANTS & REDOX SIGNALING

Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells

(2013) Mehari Endale et al.   IMMUNOBIOLOGY

Nitric Oxide Activates IL-6 Production and Expression in Human Renal Epithelial Cells

(2012) Isak Demirel et al.   AMERICAN JOURNAL OF NEPHROLOGY

Identification of 14-3-3γ as a Mieap-interacting protein and its role in mitochondrial quality control

(2012) Takafumi Miyamoto et al.   Scientific Reports

CLEC5A Regulates Japanese Encephalitis Virus-Induced Neuroinflammation and Lethality

(2012) Szu-Ting Chen et al.   PLoS Pathogens

Oxidative stress: a new risk factor for thyroid cancer

(2011) Mingzhao Xing   ENDOCRINE-RELATED CANCER

Mitochondrial reactive oxygen species drive proinflammatory cytokine production: Figure 1.

(2011) Edwina Naik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SPATA18, a Spermatogenesis-Associated Gene, Is a Novel Transcriptional Target of p53 and p63

(2011) C. Bornstein et al.   MOLECULAR AND CELLULAR BIOLOGY

Possible Existence of Lysosome-Like Organella within Mitochondria and Its Role in Mitochondrial Quality Control

(2011) Yuji Miyamoto et al.   PLoS One

Antioxidant Systems and Oxidative Stress in the Testes

(2010) R. John Aitken et al.   Oxidative Medicine and Cellular Longevity

Exogenous Antioxidants—Double-Edged Swords in Cellular Redox State: Health Beneficial Effects at Physiologic Doses versus Deleterious Effects at High Doses

(2010) Jaouad Bouayed et al.   Oxidative Medicine and Cellular Longevity

Seminal reactive oxygen species-antioxidant relationship in fertile males with and without varicocele

(2009) T. Mostafa et al.   ANDROLOGIA

Oxidative Stress: A Common Factor in Testicular Dysfunction

(2008) T. T. Turner et al.   JOURNAL OF ANDROLOGY

Two-step oligoclonal development of male germ cells

(2008) H. Ueno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL