STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle

Human papillomavirus type 18 E5 oncogene supports cell cycle progression and impairs epithelial differentiation by modulating growth factor receptor signalling during the virus life cycle

(2017) Christopher W. Wasson et al.   Oncotarget

Analysis of Multiple HPV E6 PDZ Interactions Defines Type-Specific PDZ Fingerprints That Predict Oncogenic Potential

(2016) Miranda Thomas et al.   PLoS Pathogens

Cyclin-dependent kinase 5 represses Foxp3 gene expression and Treg development through specific phosphorylation of Stat3 at Serine 727

(2015) Eric Lam et al.   MOLECULAR IMMUNOLOGY

The Human Papillomavirus E6 PDZ Binding Motif: From Life Cycle to Malignancy

(2015) Ketaki Ganti et al.   Viruses-Basel

The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes

(2015) Kathryn H. Richards et al.   Scientific Reports

Constitutive STAT3 activation in epidermal keratinocytes enhances cell clonogenicity and favours spontaneous immortalization by opposing differentiation and senescence checkpoints

(2014) Valeria Orecchia et al.   EXPERIMENTAL DERMATOLOGY

STAT3 interrupts ATR-Chk1 signaling to allow oncovirus-mediated cell proliferation

(2014) Siva Koganti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of interleukin-6/signal transducer and activator of transcription 3 by human papillomavirus early proteins 6 induces fibroblast senescence to promote cervical tumourigenesis through autocrine and paracrine pathways in tumour microenvironment

(2013) Chunxia Ren et al.   EUROPEAN JOURNAL OF CANCER

Functional Regulatory Role of STAT3 in HPV16-Mediated Cervical Carcinogenesis

(2013) Shirish Shukla et al.   PLoS One

HPV-18 E6 mutants reveal p53 modulation of viral DNA amplification in organotypic cultures

(2013) E.-Y. Kho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The E4 protein; structure, function and patterns of expression

(2013) John Doorbar   VIROLOGY

Diseases associated with human papillomavirus infection

(2013) Heather A. Cubie   VIROLOGY

Epigenetics of human papillomaviruses

(2013) Eric Johannsen et al.   VIROLOGY

The HPV16 E6 Oncoprotein Causes Prolonged Receptor Protein Tyrosine Kinase Signaling and Enhances Internalization of Phosphorylated Receptor Species

(2013) Jennifer M. Spangle et al.   PLoS Pathogens

The JAK-STAT Transcriptional Regulator, STAT-5, Activates the ATM DNA Damage Pathway to Induce HPV 31 Genome Amplification upon Epithelial Differentiation

(2013) Shiyuan Hong et al.   PLoS Pathogens

Inactivation of p53 Rescues the Maintenance of High Risk HPV DNA Genomes Deficient in Expression of E6

(2013) Laurel D. Lorenz et al.   PLoS Pathogens

Discovery of Potent and Selective Covalent Inhibitors of JNK

(2012) Tinghu Zhang et al.   CHEMISTRY & BIOLOGY

STAT3 signal transduction through interleukin-22 in oral squamous cell carcinoma

(2012) LUTFUN NAHER et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Interactions between E6AP and E6 proteins from alpha and beta HPV types

(2012) Miranda Thomas et al.   VIROLOGY

Proteomic approaches to the study of papillomavirus–host interactions

(2012) Elizabeth A. White et al.   VIROLOGY

Worldwide burden of cervical cancer in 2008

(2011) M. Arbyn et al.   ANNALS OF ONCOLOGY

A highly efficient system to produce infectious human papillomavirus: Elucidation of natural virus-host interactions

(2011) Louise T. Chow et al.   CELL CYCLE

A cyclin-binding motif in human papillomavirus type 18 (HPV18) E1^E4 is necessary for association with CDK–cyclin complexes and G2/M cell cycle arrest of keratinocytes, but is not required for differentiation-dependent viral genome amplification or L1 capsid protein expression

(2011) Gillian L. Knight et al.   VIROLOGY

STAT3 modulates the DNA damage response pathway

(2010) Seán P. Barry et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

The cdk5 Kinase Regulates the STAT3 Transcription Factor to Prevent DNA Damage upon Topoisomerase I Inhibition

(2010) Sandy Courapied et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor

(2010) Ken Miyoshi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

mTOR mediates human trophoblast invasion through regulation of matrix-remodeling enzymes and is associated with serine phosphorylation of STAT3

(2009) Susann Busch et al.   EXPERIMENTAL CELL RESEARCH

Erk1/2 MAP kinases are required for epidermal G2/M progression

(2009) Phillip A. Dumesic et al.   JOURNAL OF CELL BIOLOGY

Human Papillomaviruses Activate the ATM DNA Damage Pathway for Viral Genome Amplification upon Differentiation

(2009) Cary A. Moody et al.   PLoS Pathogens

Efficacy of TG101348, a Selective JAK2 Inhibitor, in Treatment of a Murine Model of JAK2V617F-Induced Polycythemia Vera

(2008) Gerlinde Wernig et al.   CANCER CELL

The High-Mobility Group A1a/Signal Transducer and Activator of Transcription-3 Axis: An Achilles Heel for Hematopoietic Malignancies?

(2008) J. Hillion et al.   CANCER RESEARCH

Impact of Stat3 activation upon skin biology: A dichotomy of its role between homeostasis and diseases

(2007) Shigetoshi Sano et al.   JOURNAL OF DERMATOLOGICAL SCIENCE