The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans

Dynamic Architecture of DNA Repair Complexes and the Synaptonemal Complex at Sites of Meiotic Recombination

(2018) Alexander Woglar et al.   CELL

LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis

(2018) Ye Hong et al.   Nature Communications

A SUMO-Dependent Protein Network Regulates Chromosome Congression during Oocyte Meiosis

(2017) Federico Pelisch et al.   MOLECULAR CELL

The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis

(2016) Juliane Braun et al.   PLoS One

Meiotic recombination and the crossover assurance checkpoint in Caenorhabditis elegans

(2016) Zhouliang Yu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Separable Roles for a Caenorhabditis elegans RMI1 Homolog in Promoting and Antagonizing Meiotic Crossovers Ensure Faithful Chromosome Inheritance

(2016) Marlène Jagut et al.   PLOS BIOLOGY

The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis

(2016) Ye Hong et al.   PLoS Genetics

Streamlined Genome Engineering with a Self-Excising Drug Selection Cassette

(2015) Daniel J. Dickinson et al.   GENETICS

Streamlined Genome Engineering with a Self-Excising Drug Selection Cassette

(2015) Daniel J. Dickinson et al.   GENETICS

The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins

(2014) Yumi Kim et al.   DEVELOPMENTAL CELL

DNA Helicase HIM-6/BLM Both Promotes MutSγ-Dependent Crossovers and Antagonizes MutSγ-Independent Interhomolog Associations During Caenorhabditis elegans Meiosis

(2014) Mara Schvarzstein et al.   GENETICS

Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites

(2014) J. Kim Holloway et al.   JOURNAL OF CELL BIOLOGY

Antagonistic roles of ubiquitin ligase HEI10 and SUMO ligase RNF212 regulate meiotic recombination

(2014) Huanyu Qiao et al.   NATURE GENETICS

Holliday Junction Resolvases

(2014) H. D. M. Wyatt et al.   Cold Spring Harbor Perspectives in Biology

Meiotic and Mitotic Recombination in Meiosis

(2013) K. P. Kohl et al.   GENETICS

Coordinated Actions of SLX1-SLX4 and MUS81-EME1 for Holliday Junction Resolution in Human Cells

(2013) Haley D.M. Wyatt et al.   MOLECULAR CELL

RNF212 is a dosage-sensitive regulator of crossing-over during mammalian meiosis

(2013) April Reynolds et al.   NATURE GENETICS

The C. elegans DSB-2 Protein Reveals a Regulatory Network that Controls Competence for Meiotic DSB Formation and Promotes Crossover Assurance

(2013) Simona Rosu et al.   PLoS Genetics

Joint Molecule Resolution Requires the Redundant Activities of MUS-81 and XPF-1 during Caenorhabditis elegans Meiosis

(2013) Nigel J. O'Neil et al.   PLoS Genetics

Interplay between Structure-Specific Endonucleases for Crossover Control during Caenorhabditis elegans Meiosis

(2013) Takamune T. Saito et al.   PLoS Genetics

Identification of DSB-1, a Protein Required for Initiation of Meiotic Recombination in Caenorhabditis elegans, Illuminates a Crossover Assurance Checkpoint

(2013) Ericca L. Stamper et al.   PLoS Genetics

Combinatorial Regulation of Meiotic Holliday Junction Resolution in C. elegans by HIM-6 (BLM) Helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 Nucleases

(2013) Ana Agostinho et al.   PLoS Genetics

Delineation of Joint Molecule Resolution Pathways in Meiosis Identifies a Crossover-Specific Resolvase

(2012) Kseniya Zakharyevich et al.   CELL

COSA-1 Reveals Robust Homeostasis and Separable Licensing and Reinforcement Steps Governing Meiotic Crossovers

(2012) Rayka Yokoo et al.   CELL

The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo

(2012) Andreas Brachner et al.   JOURNAL OF CELL SCIENCE

LEM-3 – A LEM Domain Containing Nuclease Involved in the DNA Damage Response in C. elegans

(2012) Christina M. Dittrich et al.   PLoS One

Regulatory Control of the Resolution of DNA Recombination Intermediates during Meiosis and Mitosis

(2011) Joao Matos et al.   CELL

Robust Crossover Assurance and Regulated Interhomolog Access Maintain Meiotic Crossover Number

(2011) S. Rosu et al.   SCIENCE

Temporally and Biochemically Distinct Activities of Exo1 during Meiosis: Double-Strand Break Resection and Resolution of Double Holliday Junctions

(2010) Kseniya Zakharyevich et al.   MOLECULAR CELL

RTEL-1 Enforces Meiotic Crossover Interference and Homeostasis

(2010) J. L. Youds et al.   SCIENCE

The Caenorhabditis elegans Homolog of Gen1/Yen1 Resolvases Links DNA Damage Signaling to DNA Double-Strand Break Repair

(2010) Aymeric P. Bailly et al.   PLoS Genetics

Distribution of meiotic recombination events: talking to your neighbors

(2009) Enrique Martinez-Perez et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The axial element protein HTP-3 promotes cohesin loading and meiotic axis assembly in C. elegans to implement the meiotic program of chromosome segregation

(2009) A. F. Severson et al.   GENES & DEVELOPMENT

Caenorhabditis elegans HIM-18/SLX-4 Interacts with SLX-1 and XPF-1 and Maintains Genomic Integrity in the Germline by Processing Recombination Intermediates

(2009) Takamune T. Saito et al.   PLoS Genetics

BRC-1 acts in the inter-sister pathway of meiotic double-strand break repair

(2008) Adele Adamo et al.   EMBO REPORTS

Identification of Holliday junction resolvases from humans and yeast

(2008) Stephen C. Y. Ip et al.   NATURE

MUS81 Generates a Subset of MLH1-MLH3–Independent Crossovers in Mammalian Meiosis

(2008) J. Kim Holloway et al.   PLoS Genetics

ZHP-3 Acts at Crossovers to Couple Meiotic Recombination with Synaptonemal Complex Disassembly and Bivalent Formation in C. elegans

(2008) Needhi Bhalla et al.   PLoS Genetics