An efficient Bayesian meta-analysis approach for studying cross-phenotype genetic associations
Published 2018 View Full Article
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Title
An efficient Bayesian meta-analysis approach for studying cross-phenotype genetic associations
Authors
Keywords
Phenotypes, Case-control studies, Genome-wide association studies, Dyslipidemia, Simulation and modeling, Genetic loci, Type 2 diabetes, Peripheral vascular disease
Journal
PLoS Genetics
Volume 14, Issue 2, Pages e1007139
Publisher
Public Library of Science (PLoS)
Online
2018-02-13
DOI
10.1371/journal.pgen.1007139
References
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Note: Only part of the references are listed.- How Can We Explain Very Low Odds Ratios in GWAS? I. Polygenic Models
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- (2015) Bjarni J. Vilhjálmsson et al. AMERICAN JOURNAL OF HUMAN GENETICS
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- A Comparison of Multivariate Genome-Wide Association Methods
- (2014) Tessel E. Galesloot et al. PLoS One
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- (2013) Ole A. Andreassen et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Common genetic variants in the 9p21 region and their associations with multiple tumours
- (2013) F Gu et al. BRITISH JOURNAL OF CANCER
- Turning of COGS moves forward findings for hormonally mediated cancers
- (2013) Lori C Sakoda et al. NATURE GENETICS
- Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
- (2013) S Hong Lee et al. NATURE GENETICS
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- (2013) Cristen J Willer et al. NATURE GENETICS
- Genetic insights into common pathways and complex relationships among immune-mediated diseases
- (2013) Miles Parkes et al. NATURE REVIEWS GENETICS
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- (2012) Samsiddhi Bhattacharjee et al. AMERICAN JOURNAL OF HUMAN GENETICS
- MultiPhen: Joint Model of Multiple Phenotypes Can Increase Discovery in GWAS
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- Abundant Pleiotropy in Human Complex Diseases and Traits
- (2011) Shanya Sivakumaran et al. AMERICAN JOURNAL OF HUMAN GENETICS
- P-value based analysis for shared controls design in genome-wide association studies
- (2010) Dmitri V. Zaykin et al. GENETIC EPIDEMIOLOGY
- Meta-Analysis of Genome-wide Association Studies with Overlapping Subjects
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- Bayesian statistical methods for genetic association studies
- (2009) Matthew Stephens et al. NATURE REVIEWS GENETICS
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