Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS

(2016) Yunpeng Wang et al.   PLoS Genetics

A Fast Method that Uses Polygenic Scores to Estimate the Variance Explained by Genome-wide Marker Panels and the Proportion of Variants Affecting a Trait

(2015) Luigi Palla et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Common genetic variants influence human subcortical brain structures

(2015) Derrek P. Hibar et al.   NATURE

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies

(2015) Wesley K. Thompson et al.   PLoS Genetics

MultiBLUP: improved SNP-based prediction for complex traits

(2014) Doug Speed et al.   GENOME RESEARCH

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Efficient multivariate linear mixed model algorithms for genome-wide association studies

(2014) Xiang Zhou et al.   NATURE METHODS

The contribution of genetic variants to disease depends on the ruler

(2014) John S. Witte et al.   NATURE REVIEWS GENETICS

Improved Detection of Common Variants Associated with Schizophrenia by Leveraging Pleiotropy with Cardiovascular-Disease Risk Factors

(2013) Ole A. Andreassen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies

(2013) Nilanjan Chatterjee et al.   NATURE GENETICS

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

(2013) Stephan Ripke et al.   NATURE GENETICS

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

The heritability of human disease: estimation, uses and abuses

(2013) Albert Tenesa et al.   NATURE REVIEWS GENETICS

Polygenic Modeling with Bayesian Sparse Linear Mixed Models

(2013) Xiang Zhou et al.   PLoS Genetics

All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs

(2013) Andrew J. Schork et al.   PLoS Genetics

Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate

(2013) Ole A. Andreassen et al.   PLoS Genetics

Using summary data from the Danish National Registers to estimate heritabilities for schizophrenia, bipolar disorder, and major depressive disorder

(2013) Naomi Wray   Frontiers in Genetics

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Living with P Values

(2012) Sander Greenland et al.   EPIDEMIOLOGY

A Better Coefficient of Determination for Genetic Profile Analysis

(2012) Sang Hong Lee et al.   GENETIC EPIDEMIOLOGY

Improving accuracy of genomic predictions within and between dairy cattle breeds with imputed high-density single nucleotide polymorphism panels

(2012) M. Erbe et al.   JOURNAL OF DAIRY SCIENCE

A mega-analysis of genome-wide association studies for major depressive disorder

(2012)   MOLECULAR PSYCHIATRY

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

(2012) S Hong Lee et al.   NATURE GENETICS

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

(2012) Eli A Stahl et al.   NATURE GENETICS

Estimating Missing Heritability for Disease from Genome-wide Association Studies

(2011) Sang Hong Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic inflation factors under polygenic inheritance

(2011) Jian Yang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Uncovering the total heritability explained by all true susceptibility variants in a genome-wide association study

(2011) Hon-Cheong So et al.   GENETIC EPIDEMIOLOGY

Genome-wide association study identifies five new schizophrenia loci

(2011)   NATURE GENETICS

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

(2011)   NATURE GENETICS

Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants

(2011) J.-H. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

(2010) Ju-Hyun Park et al.   NATURE GENETICS

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

The Psychiatric GWAS Consortium: Big Science Comes to Psychiatry

(2010) Patrick F. Sullivan   NEURON

Estimating the Total Number of Susceptibility Variants Underlying Complex Diseases from Genome-Wide Association Studies

(2010) Hon-Cheong So et al.   PLoS One

Methodological Issues in Multistage Genome-Wide Association Studies

(2010) Duncan C. Thomas et al.   STATISTICAL SCIENCE

Estimating Effects and Making Predictions from Genome-Wide Marker Data

(2010) Michael E. Goddard et al.   STATISTICAL SCIENCE

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

(2009) Paul Lichtenstein et al.   LANCET

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

(2009) Shaun M. Purcell et al.   NATURE

Estimating Odds Ratios in Genome Scans: An Approximate Conditional Likelihood Approach

(2008) Arpita Ghosh et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Accommodating Linkage Disequilibrium in Genetic-Association Analyses via Ridge Regression

(2008) Nathalie Malo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Estimation of significance thresholds for genomewide association scans

(2008) Frank Dudbridge et al.   GENETIC EPIDEMIOLOGY

Estimation of the multiple testing burden for genomewide association studies of nearly all common variants

(2008) Itsik Pe'er et al.   GENETIC EPIDEMIOLOGY