mTOR signaling regulates central and peripheral circadian clock function

NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus

(2018) Ryan S Wible et al.   eLife

Aberrant Proteostasis of BMAL1 Underlies Circadian Abnormalities in a Paradigmatic mTOR-opathy

(2017) Jonathan O. Lipton et al.   Cell Reports

TOR signaling pathway and autophagy are involved in the regulation of circadian rhythms in behavior and plasticity of L2 interneurons in the brain of Drosophila melanogaster

(2017) Ewelina Kijak et al.   PLoS One

The Pentose Phosphate Pathway Regulates the Circadian Clock

(2016) Guillaume Rey et al.   Cell Metabolism

Model-driven experimental approach reveals the complex regulatory distribution of p53 by the circadian factor Period 2

(2016) Tetsuya Gotoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BMAL1-dependent regulation of the mTOR signaling pathway delays aging

(2016) Rohini V. Khapre et al.   Aging-US

Time for Food: The Intimate Interplay between Nutrition, Metabolism, and the Circadian Clock

(2015) Gad Asher et al.   CELL

The Circadian Protein BMAL1 Regulates Translation in Response to S6K1-Mediated Phosphorylation

(2015) Jonathan O. Lipton et al.   CELL

Light-regulated translational control of circadian behavior by eIF4E phosphorylation

(2015) Ruifeng Cao et al.   NATURE NEUROSCIENCE

Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C terminus

(2015) Haiyan Xu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C terminus

(2015) Haiyan Xu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Making new contacts: the mTOR network in metabolism and signalling crosstalk

(2014) Mitsugu Shimobayashi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21

(2014) M. Cornu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A circadian gene expression atlas in mammals: Implications for biology and medicine

(2014) Ray Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Machine Learning Helps Identify CHRONO as a Circadian Clock Component

(2014) Ron C. Anafi et al.   PLOS BIOLOGY

A Novel Protein, CHRONO, Functions as a Core Component of the Mammalian Circadian Clock

(2014) Akihiro Goriki et al.   PLOS BIOLOGY

Cell Type-Specific Functions of Period Genes Revealed by Novel Adipocyte and Hepatocyte Circadian Clock Models

(2014) Chidambaram Ramanathan et al.   PLoS Genetics

Impact of fasting on the rhythmic expression of myogenic and metabolic factors in skeletal muscle of adult mice

(2013) T. Shavlakadze et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanism of the circadian clock in physiology

(2013) Jacob Richards et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Circadian Regulation of mTOR by the Ubiquitin Pathway in Renal Cell Carcinoma

(2013) Hiroyuki Okazaki et al.   CANCER RESEARCH

Competing E3 Ubiquitin Ligases Govern Circadian Periodicity by Degradation of CRY in Nucleus and Cytoplasm

(2013) Seung-Hee Yoo et al.   CELL

Translational Control of Entrainment and Synchrony of the Suprachiasmatic Circadian Clock by mTOR/4E-BP1 Signaling

(2013) Ruifeng Cao et al.   NEURON

A New Functional Role for Mechanistic/Mammalian Target of Rapamycin Complex 1 (mTORC1) in the Circadian Regulation of L-Type Voltage-Gated Calcium Channels in Avian Cone Photoreceptors

(2013) Cathy Chia-Yu Huang et al.   PLoS One

p53 regulates Period2 expression and the circadian clock

(2013) Takao Miki et al.   Nature Communications

The Circadian Clock Coordinates Ribosome Biogenesis

(2013) Céline Jouffe et al.   PLOS BIOLOGY

Central and Peripheral Circadian Clocks in Mammals

(2012) Jennifer A. Mohawk et al.   Annual Review of Neuroscience

Period determination in the food-entrainable and methamphetamine-sensitive circadian oscillator(s)

(2012) J. S. Pendergast et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct perturbation of the translatome by the antidiabetic drug metformin

(2012) O. Larsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

Altered clock gene expression and vascular smooth muscle diurnal contractile variations in type 2 diabetic db/db mice

(2011) Wen Su et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets

(2011) Ken Inoki et al.   Annual Review of Pharmacology and Toxicology

Crosstalk between Components of Circadian and Metabolic Cycles in Mammals

(2011) Gad Asher et al.   Cell Metabolism

Circadian regulation of mammalian target of rapamycin signaling in the mouse suprachiasmatic nucleus

(2011) R. Cao et al.   NEUROSCIENCE

Poly(ADP-Ribose) Polymerase 1 Participates in the Phase Entrainment of Circadian Clocks to Feeding

(2010) Gad Asher et al.   CELL

AKT and TOR Signaling Set the Pace of the Circadian Pacemaker

(2010) Xiangzhong Zheng et al.   CURRENT BIOLOGY

Mammalian Target of Rapamycin Signaling Modulates Photic Entrainment of the Suprachiasmatic Circadian Clock

(2010) R. Cao et al.   JOURNAL OF NEUROSCIENCE

Sleep and circadian rhythm disruption in psychiatric and neurodegenerative disease

(2010) Katharina Wulff et al.   NATURE REVIEWS NEUROSCIENCE

Physiology of Circadian Entrainment

(2010) Diego A. Golombek et al.   PHYSIOLOGICAL REVIEWS

Circadian Integration of Metabolism and Energetics

(2010) J. Bass et al.   SCIENCE

mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs

(2010) R. J. O. Dowling et al.   SCIENCE

A Genome-wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells

(2009) Eric E. Zhang et al.   CELL

Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1

(2009) Y. Nakahata et al.   SCIENCE

AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation

(2009) K. A. Lamia et al.   SCIENCE

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis

(2009) K. M. Ramsey et al.   SCIENCE

Harmonics of Circadian Gene Transcription in Mammals

(2009) Michael E. Hughes et al.   PLoS Genetics

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

High-Fat Diet Delays and Fasting Advances the Circadian Expression of Adiponectin Signaling Components in Mouse Liver

(2008) Maayan Barnea et al.   ENDOCRINOLOGY

Photic regulation of the mTOR signaling pathway in the suprachiasmatic circadian clock

(2008) Ruifeng Cao et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The genetics of mammalian circadian order and disorder: implications for physiology and disease

(2008) Joseph S. Takahashi et al.   NATURE REVIEWS GENETICS

Redundant Function of REV-ERBα and β and Non-Essential Role for Bmal1 Cycling in Transcriptional Regulation of Intracellular Circadian Rhythms

(2008) Andrew C. Liu et al.   PLoS Genetics