Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain
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Title
Dopamine transporter oligomerization involves the scaffold domain, but spares the bundle domain
Authors
Keywords
Dimers (Chemical physics), Cell membranes, Lipids, Oligomers, Biochemical simulations, Crystal structure, Dimerization, Dopamine transporters
Journal
PLoS Computational Biology
Volume 14, Issue 6, Pages e1006229
Publisher
Public Library of Science (PLoS)
Online
2018-06-07
DOI
10.1371/journal.pcbi.1006229
References
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Note: Only part of the references are listed.- Functional properties of dopamine transporter oligomers after copper linking
- (2017) Juan Zhen et al. JOURNAL OF NEUROCHEMISTRY
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- (2017) Andreas Anderluh et al. Nature Communications
- Excessive aggregation of membrane proteins in the Martini model
- (2017) Matti Javanainen et al. PLoS One
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- (2016) Azmat Sohail et al. PLoS Computational Biology
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- (2016) Kristyna Pluhackova et al. PLoS Computational Biology
- Properties of an Inward-Facing State of LeuT: Conformational Stability and Substrate Release
- (2015) Julie Grouleff et al. BIOPHYSICAL JOURNAL
- High-Throughput Simulations of Dimer and Trimer Assembly of Membrane Proteins. The DAFT Approach
- (2015) Tsjerk A. Wassenaar et al. Journal of Chemical Theory and Computation
- Computational Lipidomics with insane: A Versatile Tool for Generating Custom Membranes for Molecular Simulations
- (2015) Tsjerk A. Wassenaar et al. Journal of Chemical Theory and Computation
- ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
- (2015) James A. Maier et al. Journal of Chemical Theory and Computation
- Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinities
- (2015) Juan Zhen et al. JOURNAL OF NEUROCHEMISTRY
- Amphetamines, new psychoactive drugs and the monoamine transporter cycle
- (2015) Harald H. Sitte et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Tracking Single Serotonin Transporter Molecules at the Endoplasmic Reticulum and Plasma Membrane
- (2014) Andreas Anderluh et al. BIOPHYSICAL JOURNAL
- A Cytosolic Relay of Heat Shock Proteins HSP70-1A and HSP90β Monitors the Folding Trajectory of the Serotonin Transporter
- (2014) Ali El-Kasaby et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Single Molecule Analysis Reveals Coexistence of Stable Serotonin Transporter Monomers and Oligomers in the Live Cell Plasma Membrane
- (2014) Andreas Anderluh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PIP2 regulates psychostimulant behaviors through its interaction with a membrane protein
- (2014) Peter J Hamilton et al. Nature Chemical Biology
- SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking
- (2014) E Bowton et al. Translational Psychiatry
- GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit
- (2013) Sander Pronk et al. BIOINFORMATICS
- Free energy of WALP23 dimer association in DMPC, DPPC, and DOPC bilayers
- (2013) Norberto Castillo et al. CHEMISTRY AND PHYSICS OF LIPIDS
- Switching the Clientele
- (2013) Sonja Sucic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Going Backward: A Flexible Geometric Approach to Reverse Transformation from Coarse Grained to Atomistic Models
- (2013) Tsjerk A. Wassenaar et al. Journal of Chemical Theory and Computation
- Structural basis for action by diverse antidepressants on biogenic amine transporters
- (2013) Hui Wang et al. NATURE
- Amphetamine actions at the serotonin transporter rely on the availability of phosphatidylinositol-4,5-bisphosphate
- (2013) F. Buchmayer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of dopamine transporter regulation in normal and disease states
- (2013) Roxanne A. Vaughan et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Mutational Analysis of the High-Affinity Zinc Binding Site Validates a Refined Human Dopamine Transporter Homology Model
- (2013) Thomas Stockner et al. PLoS Computational Biology
- Membrane Protein Simulations Using AMBER Force Field and Berger Lipid Parameters
- (2012) Arnau Cordomí et al. Journal of Chemical Theory and Computation
- Improved Parameters for the Martini Coarse-Grained Protein Force Field
- (2012) Djurre H. de Jong et al. Journal of Chemical Theory and Computation
- X-ray structures of LeuT in substrate-free outward-open and apo inward-open states
- (2012) Harini Krishnamurthy et al. NATURE
- Assessing the Relative Stability of Dimer Interfaces in G Protein-Coupled Receptors
- (2012) Jennifer M. Johnston et al. PLoS Computational Biology
- The Serotonin Transporter Is an Exclusive Client of the Coat Protein Complex II (COPII) Component SEC24C
- (2011) Sonja Sucic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Keep It Flexible: Driving Macromolecular Rotary Motions in Atomistic Simulations with GROMACS
- (2011) Carsten Kutzner et al. Journal of Chemical Theory and Computation
- The Plasma Membrane-Associated GTPase Rin Interacts with the Dopamine Transporter and Is Required for Protein Kinase C-Regulated Dopamine Transporter Trafficking
- (2011) D. M. Navaroli et al. JOURNAL OF NEUROSCIENCE
- SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation
- (2011) A. S. Kristensen et al. PHARMACOLOGICAL REVIEWS
- Mutations in the Carboxyl-terminal SEC24 Binding Motif of the Serotonin Transporter Impair Folding of the Transporter
- (2010) Ali El-Kasaby et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- COPII-mediated vesicle formation at a glance
- (2010) D. Jensen et al. JOURNAL OF CELL SCIENCE
- g_wham—A Free Weighted Histogram Analysis Implementation Including Robust Error and Autocorrelation Estimates
- (2010) Jochen S. Hub et al. Journal of Chemical Theory and Computation
- Interrelation of dopamine transporter oligomerization and surface presence as studied with mutant transporter proteins and amphetamine
- (2010) Yan Li et al. JOURNAL OF NEUROCHEMISTRY
- Dysregulation of Dopamine Transporters via Dopamine D2 Autoreceptors Triggers Anomalous Dopamine Efflux Associated with Attention-Deficit Hyperactivity Disorder
- (2010) E. Bowton et al. JOURNAL OF NEUROSCIENCE
- Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study
- (2010) Manju A Kurian et al. LANCET NEUROLOGY
- The Rocking Bundle: A Mechanism for Ion-Coupled Solute Flux by Symmetrical Transporters
- (2009) Lucy R. Forrest et al. PHYSIOLOGY
- Dopamine spillover after quantal release: Rethinking dopamine transmission in the nigrostriatal pathway
- (2008) Margaret E. Rice et al. BRAIN RESEARCH REVIEWS
- Glycine Transporter Dimers
- (2008) Ingo Bartholomäus et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Substrates dissociate dopamine transporter oligomers
- (2008) Nianhang Chen et al. JOURNAL OF NEUROCHEMISTRY
- A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation
- (2008) S. K. Singh et al. SCIENCE
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