Multiple Sclerosis Pathology

The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain

(2016) Lukas Haider et al.   BRAIN

The search for the target antigens of multiple sclerosis, part 2: CD8+ T cells, B cells, and antibodies in the focus of reverse-translational research

(2016) Reinhard Hohlfeld et al.   LANCET NEUROLOGY

Progressive multifocal leukoencephalopathy and immune reconstitution inflammatory syndrome (IRIS)

(2015) Jan Bauer et al.   ACTA NEUROPATHOLOGICA

Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid cause demyelination of spinal cord explants

(2015) Kevin Blauth et al.   ACTA NEUROPATHOLOGICA

Melanoma cell adhesion molecule-positive CD8 T lymphocytes mediate central nervous system inflammation

(2015) Catherine Larochelle et al.   ANNALS OF NEUROLOGY

Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque

(2015) Josa M. Frischer et al.   ANNALS OF NEUROLOGY

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

Demyelination during multiple sclerosis is associated with combined activation of microglia/macrophages by IFN-γ and alpha B-crystallin

(2014) Malika Bsibsi et al.   ACTA NEUROPATHOLOGICA

Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics

(2014) Oscar G. Vidaurre et al.   BRAIN

Multiple sclerosis deep grey matter: the relation between demyelination, neurodegeneration, inflammation and iron

(2014) Lukas Haider et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

(2013) Tatsuro Misu et al.   ACTA NEUROPATHOLOGICA

Disease-specific molecular events in cortical multiple sclerosis lesions

(2013) Marie Therese Fischer et al.   BRAIN

Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system

(2012) Catherine Larochelle et al.   BRAIN

Functional identification of pathogenic autoantibody responses in patients with multiple sclerosis

(2012) Christina Elliott et al.   BRAIN

Secretory products of multiple sclerosis B cells are cytotoxic to oligodendroglia in vitro

(2012) Robert P. Lisak et al.   JOURNAL OF NEUROIMMUNOLOGY

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

Will the real multiple sclerosis please stand up?

(2012) Peter K. Stys et al.   NATURE REVIEWS NEUROSCIENCE

IL-21 and IL-21 Receptor Expression in Lymphocytes and Neurons in Multiple Sclerosis Brain

(2011) John S. Tzartos et al.   AMERICAN JOURNAL OF PATHOLOGY

The Relationship between Normal Cerebral Perfusion Patterns and White Matter Lesion Distribution in 1,249 Patients with Multiple Sclerosis

(2011) Christopher M. Holland et al.   JOURNAL OF NEUROIMAGING

Inflammatory Cortical Demyelination in Early Multiple Sclerosis

(2011) Claudia F. Lucchinetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intracerebral Human Regulatory T Cells: Analysis of CD4+CD25+FOXP3+ T Cells in Brain Lesions and Cerebrospinal Fluid of Multiple Sclerosis Patients

(2011) Benedikt Fritzsching et al.   PLoS One

Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords

(2010) Géraldine Androdias et al.   ANNALS OF NEUROLOGY

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

(2010) Graham R. Campbell et al.   ANNALS OF NEUROLOGY

Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patients

(2010) Ranjan Dutta et al.   ANNALS OF NEUROLOGY

The blood–brain barrier, chemokines and multiple sclerosis

(2010) David W. Holman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Demyelination versus remyelination in progressive multiple sclerosis

(2010) Stephan Bramow et al.   BRAIN

Wallerian Degeneration: A Major Component of Early Axonal Pathology in Multiple Sclerosis

(2010) Tomasz Dziedzic et al.   BRAIN PATHOLOGY

Multiple sclerosis: Distribution of inflammatory cells in newly forming lesions

(2009) Andrew P. D. Henderson et al.   ANNALS OF NEUROLOGY

The relation between inflammation and neurodegeneration in multiple sclerosis brains

(2009) Josa M. Frischer et al.   BRAIN

Demyelination, Inflammation, and Neurodegeneration in Multiple Sclerosis Deep Gray Matter

(2009) Marco Vercellino et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

(2009) Bruce D Trapp et al.   LANCET NEUROLOGY

Mitochondrial defects in acute multiple sclerosis lesions

(2008) Don Mahad et al.   BRAIN

B cells and multiple sclerosis

(2008) Diego Franciotta et al.   LANCET NEUROLOGY

Interleukin-17 Production in Central Nervous System-Infiltrating T Cells and Glial Cells Is Associated with Active Disease in Multiple Sclerosis

(2007) John S. Tzartos et al.   AMERICAN JOURNAL OF PATHOLOGY

Cortical demyelination in PML and MS: Similarities and differences

(2007) N. M. Moll et al.   NEUROLOGY