Beyond sepsis: Staphylococcus epidermidis is an underestimated but significant contributor to neonatal morbidity

Late-onset Sepsis in Extremely Premature Infants

(2017) Rachel G. Greenberg et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Late-onset Neonatal Sepsis—A 10-year Review From North Queensland, Australia

(2017) Harsha Gowda et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Toxin Mediates Sepsis Caused by Methicillin-Resistant Staphylococcus epidermidis

(2017) Li Qin et al.   PLoS Pathogens

Host Response to Staphylococcus epidermidis Colonization and Infections

(2017) Thuan H. Nguyen et al.   Frontiers in Cellular and Infection Microbiology

Longitudinal development of the gut microbiome and metabolome in preterm neonates with late onset sepsis and healthy controls

(2017) Christopher J. Stewart et al.   Microbiome

Cerebral ultrasound abnormalities in preterm infants caused by late-onset sepsis

(2017) L. C. Claessens et al.   PLoS One

Molecular epidemiology ofStaphylococcus epidermidisin neonatal intensive care units

(2016) Hiie Soeorg et al.   APMIS

The impact of a sepsis quality improvement project on neurodisability rates in very low birthweight infants

(2016) Jonathan W Davis et al.   Archives of Disease in Childhood-Fetal and Neonatal Edition

Neonatal bloodstream infections in a Ghanaian Tertiary Hospital: Are the current antibiotic recommendations adequate?

(2016) Appiah-Korang Labi et al.   BMC INFECTIOUS DISEASES

Pathogen and antimicrobial resistance profiles of culture-proven neonatal sepsis in Southwest China, 1990-2014

(2016) Qi Lu et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Global, regional, and national causes of under-5 mortality in 2000–15: an updated systematic analysis with implications for the Sustainable Development Goals

(2016) Li Liu et al.   LANCET

The Vulnerable Newborn Brain: Imaging Patterns of Acquired Perinatal Injury

(2016) Donna M. Ferriero   Neonatology

Surgical Necrotizing Enterocolitis versus Spontaneous Intestinal Perforation in White Matter Injury on Brain Magnetic Resonance Imaging

(2016) Seung Han Shin et al.   Neonatology

Aggressive Posterior Retinopathy of Prematurity Is Associated with Multiple Infectious Episodes and Thrombocytopenia

(2016) Pia Lundgren et al.   Neonatology

Retinopathy of Prematurity: Therapeutic Strategies Based on Pathophysiology

(2016) Rowena Cayabyab et al.   Neonatology

Factors associated with inter-institutional variations in sepsis rates of very-low-birth-weight infants in 34 Malaysian neonatal intensive care units

(2016) NY Boo et al.   SINGAPORE MEDICAL JOURNAL

Clinical Relevance of Pathogens Detected by Multiplex PCR in Blood of Very-Low-Birth Weight Infants with Suspected Sepsis – Multicentre Study of the German Neonatal Network

(2016) Birte Tröger et al.   PLoS One

Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012

(2015) Barbara J. Stoll et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Staphylococcus epidermidisBacteremia Induces Brain Injury in Neonatal Mice via Toll-like Receptor 2-Dependent and -Independent Pathways

(2015) Dan Bi et al.   JOURNAL OF INFECTIOUS DISEASES

Blood Culture Proven Early Onset Sepsis and Late Onset Sepsis in Very-Low-Birth-Weight Infants in Korea

(2015) Soon Min Lee et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Peptide length and folding state govern the capacity of staphylococcal β-type phenol-soluble modulins to activate human formyl-peptide receptors 1 or 2

(2015) Dorothee Kretschmer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

NOD1 and NOD2 expression and function in very preterm infant mononuclear cells

(2014) Caitlyn Granland et al.   ACTA PAEDIATRICA

Late-onset neonatal sepsis: recent developments

(2014) Ying Dong et al.   Archives of Disease in Childhood-Fetal and Neonatal Edition

Late-onset bloodstream infections of Very-Low-Birth-Weight infants: data from the Polish Neonatology Surveillance Network in 2009–2011

(2014) Jadwiga Wójkowska-Mach et al.   BMC INFECTIOUS DISEASES

The role of Staphylococcus epidermidis in neonatal sepsis: Guarding angel or pathogenic devil?

(2014) Ying Dong et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Infection-induced inflammation and cerebral injury in preterm infants

(2014) Tobias Strunk et al.   LANCET INFECTIOUS DISEASES

A Prime Time for Trained Immunity: Innate Immune Memory in Newborns and Infants

(2014) Ofer Levy et al.   Neonatology

Microbiological Spectrum and Antibiotic Sensitivity in Endophthalmitis

(2014) Ronald C. Gentile et al.   OPHTHALMOLOGY

The airway microbiome of intubated premature infants: characteristics and changes that predict the development of bronchopulmonary dysplasia

(2014) Pablo Lohmann et al.   PEDIATRIC RESEARCH

Staphylococcus epidermidisandStaphylococcus aureustrigger different interleukin-8 and intercellular adhesion molecule-1 in lung cells: implications for inflammatory complications following neonatal sepsis

(2013) Mikael Ivarsson et al.   ACTA PAEDIATRICA

Modulation of ENaC, CFTR, and iNOS expression in bronchial epithelial cells after stimulation withStaphylococcus epidermidis(94B080) andStaphylococcus aureus(90B083)

(2013) Rashida Hussain et al.   APMIS

Neonatal Host Defense against Staphylococcal Infections

(2013) Melanie R. Power Coombs et al.   Clinical & Developmental Immunology

Toll-like receptor signaling in neonatal sepsis and inflammation: a matter of orchestration and conditioning

(2013) Kirsten Glaser et al.   Expert Review of Clinical Immunology

Distinct Signaling Cascades Elicited by Different Formyl Peptide Receptor 2 (FPR2) Agonists

(2013) Fabio Cattaneo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neurodevelopmental outcomes of very low birth weight infants with neonatal sepsis: systematic review and meta-analysis

(2013) B Alshaikh et al.   Journal of Perinatology

Coagulase-negative staphylococcus sepsis in preterm infants and long-term neurodevelopmental outcome

(2013) B Alshaikh et al.   Journal of Perinatology

Retinopathy of prematurity

(2013) Ann Hellström et al.   LANCET

Phagocytosis of neonatal pathogens by peripheral blood neutrophils and monocytes from newborn preterm and term infants

(2013) Amy Prosser et al.   PEDIATRIC RESEARCH

Neonatal Infection and 5-year Neurodevelopmental Outcome of Very Preterm Infants

(2013) A. Mitha et al.   PEDIATRICS

Culture-proven neonatal sepsis in preterm infants in a neonatal intensive care unit over a 7 year period: Coagulase-negativeStaphylococcusas the predominant pathogen

(2013) Hilal Ozkan et al.   PEDIATRICS INTERNATIONAL

A Novel Lipopeptide from Skin Commensal Activates TLR2/CD36-p38 MAPK Signaling to Increase Antibacterial Defense against Bacterial Infection

(2013) Dongqing Li et al.   PLoS One

Complement C5a Generation by Staphylococcal Biofilms

(2013) Ashley E. Satorius et al.   SHOCK

Neonatal sepsis

(2013) Birju A Shah et al.   Virulence

Role of interleukin-10 in the pathogenesis of necrotizing enterocolitis

(2012) Claudia N. Emami et al.   AMERICAN JOURNAL OF SURGERY

Neonatal infections in China, Malaysia, Hong Kong and Thailand

(2012) Abdullah Al-Taiar et al.   Archives of Disease in Childhood-Fetal and Neonatal Edition

Early and late onset sepsis in very-low-birth-weight infants from a large group of neonatal intensive care units

(2012) C.P. Hornik et al.   EARLY HUMAN DEVELOPMENT

Bacterial adhesion, intracellular survival and cytokine induction upon stimulation of mononuclear cells with planktonic or biofilm phase Staphylococcus epidermidis

(2012) Anastasia I. Spiliopoulou et al.   FEMS MICROBIOLOGY LETTERS

Responsiveness of human monocytes to the commensal bacterium Staphylococcus epidermidis develops late in gestation

(2012) Tobias Strunk et al.   PEDIATRIC RESEARCH

A Neonatal Model of Intravenous Staphylococcus epidermidis Infection in Mice

(2012) Kenny D. Kronforst et al.   PLoS One

Persistent coagulase-negative staphylococci bacteremia in very-low-birth-weight infants

(2011) Nehama Linder et al.   EUROPEAN JOURNAL OF PEDIATRICS

The Virulence Regulator Agr Controls the Staphylococcal Capacity to Activate Human Neutrophils via the Formyl Peptide Receptor 2

(2011) Dorothee Kretschmer et al.   Journal of Innate Immunity

Diversity of the Human Skin Microbiome Early in Life

(2011) Kimberly A. Capone et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Impact of Sepsis on Neurodevelopmental Outcome in a Swiss National Cohort of Extremely Premature Infants

(2011) L. J. Schlapbach et al.   PEDIATRICS

The Mechanism of Excessive Intestinal Inflammation in Necrotizing Enterocolitis: An Immature Innate Immune Response

(2011) Nanda Nanthakumar et al.   PLoS One

Molecular basis of Staphylococcus epidermidis infections

(2011) Michael Otto   Seminars in Immunopathology

Understanding the significance of Staphylococcus epidermidis bacteremia in babies and children

(2010) Gordon YC Cheung et al.   CURRENT OPINION IN INFECTIOUS DISEASES

The modulatory effect of lipids and glucose on the neonatal immune response induced by Staphylococcus epidermidis

(2010) Berit Haase et al.   INFLAMMATION RESEARCH

Method of bacterial killing differentially affects the human innate immune response to Staphylococcus epidermidis

(2010) Tobias Strunk et al.   Innate Immunity

Success through diversity – How Staphylococcus epidermidis establishes as a nosocomial pathogen

(2010) Sonja M.K. Schoenfelder et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Staphylococcus epidermidis Esp inhibits Staphylococcus aureus biofilm formation and nasal colonization

(2010) Tadayuki Iwase et al.   NATURE

Risk Factors Associated with Development of Persistent Coagulase-Negative Staphylococci Bacteremia in the Neonate and Associated Short-Term and Discharge Morbidities

(2010) Ann Anderson-Berry et al.   Neonatology

Expression of Toll-like receptors by neonatal leukocytes

(2010) Pallave Dasari et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Human Neonatal Peripheral Blood Leukocytes Demonstrate Pathogen-Specific Coordinate Expression of TLR2, TLR4/MD2, and MyD88 During Bacterial Infection In Vivo

(2010) Jin-Ping Zhang et al.   PEDIATRIC RESEARCH

TLR2 Mediates Recognition of Live Staphylococcus epidermidis and Clearance of Bacteremia

(2010) Tobias Strunk et al.   PLoS One

Staphylococcus epidermidis Strategies to Avoid Killing by Human Neutrophils

(2010) Gordon Y. C. Cheung et al.   PLoS Pathogens

Neonatal Cord Blood Subsets and Cytokine Response to Bacterial Antigens

(2009) John Peoples et al.   AMERICAN JOURNAL OF PERINATOLOGY

Reduced levels of antimicrobial proteins and peptides in human cord blood plasma

(2009) T Strunk et al.   Archives of Disease in Childhood-Fetal and Neonatal Edition

Selective Antimicrobial Action Is Provided by Phenol-Soluble Modulins Derived from Staphylococcus epidermidis, a Normal Resident of the Skin

(2009) Anna L. Cogen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Molecular characterization of Staphylococcus epidermidis strains isolated from a teaching hospital in Shanghai, China

(2009) M. Li et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Commensal bacteria regulate Toll-like receptor 3–dependent inflammation after skin injury

(2009) Yuping Lai et al.   NATURE MEDICINE

Chorioamnionitis, Postnatal Factors and Proinflammatory Response in the Pathogenetic Sequence of Bronchopulmonary Dysplasia

(2009) Christian P. Speer   Neonatology

Microecology, intestinal epithelial barrier and necrotizing enterocolitis

(2009) Renu Sharma et al.   PEDIATRIC SURGERY INTERNATIONAL

Topographical and Temporal Diversity of the Human Skin Microbiome

(2009) E. A. Grice et al.   SCIENCE

Mobile Genetic Element-Encoded Cytolysin Connects Virulence to Methicillin Resistance in MRSA

(2009) Shu Y. Queck et al.   PLoS Pathogens

Staphylococcus epidermidispolysaccharide intercellular adhesin induces IL-8 expression in human astrocytes via a mechanism involving TLR2

(2008) Niall T. Stevens et al.   CELLULAR MICROBIOLOGY

NOD-like receptors (NLRs): bona fide intracellular microbial sensors

(2008) Michael H Shaw et al.   CURRENT OPINION IN IMMUNOLOGY

A polymer-type water-soluble peptidoglycan exhibited both Toll-like receptor 2- and NOD2-agonistic activities, resulting in synergistic activation of human monocytic cells

(2008) Mizuho Natsuka et al.   Innate Immunity

Adverse Neurodevelopment in Preterm Infants with Postnatal Sepsis or Necrotizing Enterocolitis is Mediated by White Matter Abnormalities on Magnetic Resonance Imaging at Term

(2008) Divyen K. Shah et al.   JOURNAL OF PEDIATRICS

Potential of immunomodulatory agents for prevention and treatment of neonatal sepsis

(2008) J L Wynn et al.   Journal of Perinatology