Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1
Authors
Keywords
hPSCs, Beta cells, Diabetes, Differentiation, Transcription factors, Pancreatic epithelium
Journal
Stem Cell Research & Therapy
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-01-23
DOI
10.1186/s13287-017-0759-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Critical role of β1 integrin in postnatal beta-cell function and expansion
- (2017) Jason Peart et al. Oncotarget
- miR-18a counteracts AKT and ERK activation to inhibit the proliferation of pancreatic progenitor cells
- (2017) Xuyan Li et al. Scientific Reports
- Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development
- (2017) Angela J Churchill et al. eLife
- Human pluripotent stem cell differentiation to functional pancreatic cells for diabetes therapies: Innovations, challenges and future directions
- (2017) Elena F. Jacobson et al. Journal of Biological Engineering
- Rho-Associated Kinases and Non-muscle Myosin IIs Inhibit the Differentiation of Human iPSCs to Pancreatic Endoderm
- (2017) Taro Toyoda et al. Stem Cell Reports
- Long-Term Culture of Self-renewing Pancreatic Progenitors Derived from Human Pluripotent Stem Cells
- (2017) Jamie Trott et al. Stem Cell Reports
- Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes
- (2016) Zengrong Zhu et al. Cell Stem Cell
- Pdx1 regulates pancreas tubulogenesis and E-cadherin expression
- (2016) Leilani Marty-Santos et al. DEVELOPMENT
- Generation of polyhormonal and multipotent pancreatic progenitor lineages from human pluripotent stem cells
- (2016) Roman Korytnikov et al. METHODS
- ECM Signaling Regulates Collective Cellular Dynamics to Control Pancreas Branching Morphogenesis
- (2016) Hung Ping Shih et al. Cell Reports
- Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro
- (2015) H. A. Russ et al. EMBO JOURNAL
- Cell aggregation optimizes the differentiation of human ESCs and iPSCs into pancreatic bud-like progenitor cells
- (2015) Taro Toyoda et al. Stem Cell Research
- Efficient Generation of NKX6-1+ Pancreatic Progenitors from Multiple Human Pluripotent Stem Cell Lines
- (2015) M. Cristina Nostro et al. Stem Cell Reports
- PDX1 Binds and Represses Hepatic Genes to Ensure Robust Pancreatic Commitment in Differentiating Human Embryonic Stem Cells
- (2015) Adrian Kee Keong Teo et al. Stem Cell Reports
- Advances and challenges in the differentiation of pluripotent stem cells into pancreatic β cells
- (2015) Essam M Abdelalim World Journal of Stem Cells
- Extracellular matrix: A dynamic microenvironment for stem cell niche
- (2014) Francesca Gattazzo et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Generation of Functional Human Pancreatic β Cells In Vitro
- (2014) Felicia W. Pagliuca et al. CELL
- Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
- (2014) Alireza Rezania et al. NATURE BIOTECHNOLOGY
- Pancreatic Insulin-Producing Cells Differentiated from Human Embryonic Stem Cells Correct Hyperglycemia in SCID/NOD Mice, an Animal Model of Diabetes
- (2014) Xiu-feng Hua et al. PLoS One
- Differentiated human stem cells resemble fetal, not adult, β cells
- (2014) Sinisa Hrvatin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pluripotent Stem Cells as a Potential Tool for Disease Modelling and Cell Therapy in Diabetes
- (2014) Essam M. Abdelalim et al. Stem Cell Reviews and Reports
- Knockdown of p53 suppresses Nanog expression in embryonic stem cells
- (2013) Essam Mohamed Abdelalim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The influence of matrix properties on growth and morphogenesis of human pancreatic ductal epithelial cells in 3D
- (2013) Asad Raza et al. BIOMATERIALS
- Development of the Human Pancreas From Foregut to Endocrine Commitment
- (2013) R. E. Jennings et al. DIABETES
- Role of the extracellular matrix in regulating stem cell fate
- (2013) Fiona M. Watt et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Initial Cell Seeding Density Influences Pancreatic Endocrine Development During in vitro Differentiation of Human Embryonic Stem Cells
- (2013) Blair K. Gage et al. PLoS One
- Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo
- (2013) Alireza Rezania et al. STEM CELLS
- Extracellular Matrix-Mediated Differentiation of Human Embryonic Stem Cells: Differentiation to Insulin-Secreting Beta Cells
- (2013) Karthikeyan Narayanan et al. TISSUE ENGINEERING PART A
- Nkx6.1 Is Essential for Maintaining the Functional State of Pancreatic Beta Cells
- (2013) Brandon L. Taylor et al. Cell Reports
- The p53 inhibitor, pifithrin-α, suppresses self-renewal of embryonic stem cells
- (2012) Essam Mohamed Abdelalim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Transient overexpression of cyclin D2/CDK4/GLP1 genes induces proliferation and differentiation of adult pancreatic progenitors and mediates islet regeneration
- (2012) Shuyuan Chen et al. CELL CYCLE
- Maturation of Human Embryonic Stem Cell-Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice
- (2012) A. Rezania et al. DIABETES
- A Scalable System for Production of Functional Pancreatic Progenitors from Human Embryonic Stem Cells
- (2012) Thomas C. Schulz et al. PLoS One
- Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish
- (2011) Robin A Kimmel et al. BMC BIOLOGY
- Stage-specific signaling through TGF family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells
- (2011) M. C. Nostro et al. DEVELOPMENT
- Noggin, Retinoids, and Fibroblast Growth Factor Regulate Hepatic or Pancreatic Fate of Human Embryonic Stem Cells
- (2010) Josué Kunjom Mfopou et al. GASTROENTEROLOGY
- Generation of Homogeneous PDX1+ Pancreatic Progenitors from Human ES Cell-derived Endoderm Cells
- (2009) Jun Cai et al. Journal of Molecular Cell Biology
- Transcription factor expression in the developing human fetal endocrine pancreas
- (2008) B. M. Lyttle et al. DIABETOLOGIA
- Effect of Extracellular Matrix and 3D Morphogenesis on Islet Hormone Gene Expression by Ngn3-Infected Mouse Pancreatic Ductal Epithelial Cells
- (2008) Michael Ian Boretti et al. TISSUE ENGINEERING PART A
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now