Differentiation of human pluripotent stem cells into two distinct NKX6.1 populations of pancreatic progenitors

Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1

(2018) Bushra Memon et al.   Stem Cell Research & Therapy

Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development

(2017) Angela J Churchill et al.   eLife

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

(2015) H. A. Russ et al.   EMBO JOURNAL

Cell aggregation optimizes the differentiation of human ESCs and iPSCs into pancreatic bud-like progenitor cells

(2015) Taro Toyoda et al.   Stem Cell Research

Efficient Generation of NKX6-1+ Pancreatic Progenitors from Multiple Human Pluripotent Stem Cell Lines

(2015) M. Cristina Nostro et al.   Stem Cell Reports

Advances and challenges in the differentiation of pluripotent stem cells into pancreatic β cells

(2015) Essam M Abdelalim   World Journal of Stem Cells

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

Pluripotent Stem Cells as a Potential Tool for Disease Modelling and Cell Therapy in Diabetes

(2014) Essam M. Abdelalim et al.   Stem Cell Reviews and Reports

Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture

(2014) Hiroki Takeuchi et al.   Scientific Reports

Development of the Human Pancreas From Foregut to Endocrine Commitment

(2013) R. E. Jennings et al.   DIABETES

Maturation and function of human embryonic stem cell-derived pancreatic progenitors in macroencapsulation devices following transplant into mice

(2013) Jennifer E. Bruin et al.   DIABETOLOGIA

Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo

(2013) Alireza Rezania et al.   STEM CELLS

State of the Art of Clinical Islet Transplantation and Novel Protocols of Immunosuppression

(2011) A. M. James Shapiro   Current Diabetes Reports

Encapsulated pancreatic progenitors derived from human embryonic stem cells as a therapy for insulin-dependent diabetes

(2011) Bernard E. Tuch et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells

(2011) Olivia G Kelly et al.   NATURE BIOTECHNOLOGY

β-Cell failure in type 2 diabetes

(2011) Gil Leibowitz et al.   Journal of Diabetes Investigation

Nkx6 Transcription Factors and Ptf1a Function as Antagonistic Lineage Determinants in Multipotent Pancreatic Progenitors

(2010) Ashleigh E. Schaffer et al.   DEVELOPMENTAL CELL

Production of Functional Glucagon-Secreting  -Cells From Human Embryonic Stem Cells

(2010) A. Rezania et al.   DIABETES

Noggin, Retinoids, and Fibroblast Growth Factor Regulate Hepatic or Pancreatic Fate of Human Embryonic Stem Cells

(2010) Josué Kunjom Mfopou et al.   GASTROENTEROLOGY

In vitro expression of NGN3 identifies RAB3B as the predominant Ras-associated GTP-binding protein 3 family member in human islets

(2010) Karen Piper Hanley et al.   JOURNAL OF ENDOCRINOLOGY

Pancreatic islet plasticity: Interspecies comparison of islet architecture and composition

(2010) Donald J. Steiner et al.   Islets

Derivation of insulin-producing cells from human embryonic stem cells

(2009) Dennis Van Hoof et al.   Stem Cell Research

Transcription factor expression in the developing human fetal endocrine pancreas

(2008) B. M. Lyttle et al.   DIABETOLOGIA

On the origin of the   cell

(2008) J. M. Oliver-Krasinski et al.   GENES & DEVELOPMENT

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

(2008) Evert Kroon et al.   NATURE BIOTECHNOLOGY