The differentiation of mesenchymal stem cells to vascular cells regulated by the HMGB1/RAGE axis: its application in cell therapy for transplant arteriosclerosis

The Influence of Timing and Frequency of Adipose-Derived Mesenchymal Stem Cell Therapy on Immunomodulation Outcomes After Vascularized Composite Allotransplantation

(2017) Jan A. Plock et al.   TRANSPLANTATION

Mesenchymal Stromal Cell Therapy for Chronic Lung Allograft Dysfunction: Results of a First-in-Man Study

(2017) Daniel C. Chambers et al.   Stem Cells Translational Medicine

Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease

(2016) Rafael Kramann et al.   Cell Stem Cell

Endothelial-like cells differentiated from mesenchymal stem cells attenuate neointimal hyperplasia after vascular injury

(2016) Jianzhong Xu et al.   Molecular Medicine Reports

In Vivo Interleukin-13-Primed Macrophages Contribute to Reduced Alloantigen-Specific T Cell Activation and Prolong Immunological Survival of Allogeneic Mesenchymal Stem Cell Implants

(2016) Chloé J. Hoornaert et al.   STEM CELLS

Differentiation of Vascular Stem Cells Contributes to Ectopic Calcification of Atherosclerotic Plaque

(2016) Aleksandra Leszczynska et al.   STEM CELLS

Receptor for Advanced Glycation End Products-Mediated Signaling Impairs the Maintenance of Bone Marrow Mesenchymal Stromal Cells in Diabetic Model Mice

(2016) Eriko Aikawa et al.   STEM CELLS AND DEVELOPMENT

HMGB1 promotes the secretion of multiple cytokines and potentiates the osteogenic differentiation of mesenchymal stem cells through the Ras/MAPK signaling pathway

(2016) Lin Feng et al.   Experimental and Therapeutic Medicine

Blockade of Extracellular HMGB1 Suppresses Xenoreactive B Cell Responses and Delays Acute Vascular Xenogeneic Rejection

(2015) J.-H. Li et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The Role of HMGB1 in Cardiovascular Biology: Danger Signals

(2015) Jingjing Cai et al.   ANTIOXIDANTS & REDOX SIGNALING

Immunomodulatory Effects of Different Cellular Therapies of Bone Marrow Origin on Chimerism Induction and Maintenance Across MHC Barriers in a Face Allotransplantation Model

(2015) Mikael Hivelin et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Necrotic cell-derived high mobility group box 1 attracts antigen-presenting cells but inhibits hepatocyte growth factor-mediated tropism of mesenchymal stem cells for apoptotic cell death

(2015) S Vogel et al.   CELL DEATH AND DIFFERENTIATION

High Mobility Group Box 1 Promotes Angiogenesis from Bone Marrow-derived Endothelial Progenitor Cells after Myocardial Infarction

(2015) Yuichi Nakamura et al.   Journal of Atherosclerosis and Thrombosis

HMGB1-Mediated Early Loss of Transplanted Islets Is Prevented by Anti–IL-6R Antibody in Mice

(2015) Takeshi Itoh et al.   PANCREAS

Mesenchymal stem/stromal cells precondition lung monocytes/macrophages to produce tolerance against allo- and autoimmunity in the eye

(2015) Jung Hwa Ko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunological and Fibrotic Mechanisms in Cardiac Allograft Vasculopathy

(2015) Manon A. A. Jansen et al.   TRANSPLANTATION

HMGB1 and injury amplification

(2015) Peter Huebener et al.   Oncotarget

Mesenchymal Stem Cells Reduce Murine Atherosclerosis Development

(2015) Vanessa Frodermann et al.   Scientific Reports

Immune-Mediated Vascular Injury and Dysfunction in Transplant Arteriosclerosis

(2015) Anna von Rossum et al.   Frontiers in Immunology

Systemic high-mobility group box 1 administration suppresses skin inflammation by inducing an accumulation of PDGFRα+ mesenchymal cells from bone marrow

(2015) Eriko Aikawa et al.   Scientific Reports

HMGB1 Is Involved in Chronic Rejection of Cardiac Allograft via Promoting Inflammatory-Like mDCs

(2014) H. Zou et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Distinct Expression Patterns of Alveolar “Alarmins” in Subtypes of Chronic Lung Allograft Dysfunction

(2014) T. Saito et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Cell migration to CXCL12 requires simultaneous IKKα and IKKβ-dependent NF-κB signaling

(2014) Marianna Penzo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Activated Platelets Interfere with Recruitment of Mesenchymal Stem Cells to Apoptotic Cardiac Cells via High Mobility Group Box 1/Toll-like Receptor 4-mediated Down-regulation of Hepatocyte Growth Factor Receptor MET

(2014) Sebastian Vogel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-mobility group box 1 accelerates early acute allograft rejection via enhancing IL-17+γδ T-cell response

(2014) Quansong Xia et al.   TRANSPLANT INTERNATIONAL

Coronary cardiac allograft vasculopathy versus native atherosclerosis: difficulties in classification

(2014) Annalisa Angelini et al.   VIRCHOWS ARCHIV

Mesenchymal Stem Cells Ameliorate Atherosclerotic Lesions via Restoring Endothelial Function

(2014) Yu-Ling Lin et al.   Stem Cells Translational Medicine

Monocyte Chemoattractant Protein 1–Mediated Migration of Mesenchymal Stem Cells Is a Source of Intimal Hyperplasia

(2013) Monika K. Grudzinska et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Six-Month Feeding of Low-Dose Fish Oil Decreases Vascular Expression of High Mobility Group Box1 and Receptor for Advanced Glycation End-Products in Rat Chronic Allograft Vasculopathy

(2013) W. Wei et al.   TRANSPLANTATION PROCEEDINGS

Vascular Smooth Muscle Cell Apoptosis Promotes Transplant Arteriosclerosis Through Inducing the Production of SDF-1α

(2012) J. Li et al.   AMERICAN JOURNAL OF TRANSPLANTATION

HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

(2012) Milena Schiraldi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Down-regulation of vascular HMGB1 and RAGE expression by n-3 polyunsaturated fatty acids is accompanied by amelioration of chronic vasculopathy of small bowel allografts

(2012) Wei Wei et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Adventitial Pericyte Progenitor/Mesenchymal Stem Cells Participate in the Restenotic Response to Arterial Injury

(2012) Ulrich Tigges et al.   JOURNAL OF VASCULAR RESEARCH

Astrocytic high-mobility group box 1 promotes endothelial progenitor cell-mediated neurovascular remodeling during stroke recovery

(2012) K. Hayakawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differentiation of multipotent vascular stem cells contributes to vascular diseases

(2012) Zhenyu Tang et al.   Nature Communications

Human mesenchymal stem cells respond to native but not oxidized damage associated molecular pattern molecules from necrotic (tumor) material

(2011) Ramin Lotfi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Requirement of HMGB1 for stromal cell-derived factor-1/CXCL12-dependent migration of macrophages and dendritic cells

(2009) Lara Campana et al.   JOURNAL OF LEUKOCYTE BIOLOGY

High Mobility Group Box 1 Protein Inhibits the Proliferation of Human Mesenchymal Stem Cells and Promotes Their Migration and Differentiation along Osteoblastic Pathway

(2008) Erhong Meng et al.   STEM CELLS AND DEVELOPMENT