Detection of genetic cardiac diseases by Ca2+ transient profiles using machine learning methods

On Biometrics With Eye Movements

(2017) Youming Zhang et al.   IEEE Journal of Biomedical and Health Informatics

In Vivo Cellular Reprogramming: The Next Generation

(2016) Deepak Srivastava et al.   CELL

Clinical and Mechanistic Insights Into the Genetics of Cardiomyopathy

(2016) Michael A. Burke et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Insights Into Molecular, Cellular, and Functional Phenotypes

(2015) I. Karakikes et al.   CIRCULATION RESEARCH

Signal analysis and classification methods for the calcium transient data of stem cell-derived cardiomyocytes

(2015) Martti Juhola et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

Functional abnormalities in iPSC-derived cardiomyocytes generated from CPVT1 and CPVT2 patients carrying ryanodine or calsequestrin mutations

(2015) Atara Novak et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Monitoring Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Genetically Encoded Calcium and Voltage Fluorescent Reporters

(2015) Rami Shinnawi et al.   Stem Cell Reports

Antiarrhythmic Effects of Dantrolene in Patients with Catecholaminergic Polymorphic Ventricular Tachycardia and Replication of the Responses Using iPSC Models

(2015) Kirsi Penttinen et al.   PLoS One

Supervised Machine Learning for Classification of the Electrophysiological Effects of Chronotropic Drugs on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

(2015) Christopher Heylman et al.   PLoS One

Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells

(2014) Lu Han et al.   CARDIOVASCULAR RESEARCH

Human Stem Cell-Derived Cardiomyocytes in Cellular Impedance Assays: Bringing Cardiotoxicity Screening to the Front Line

(2014) Matthew F. Peters et al.   Cardiovascular Toxicology

Evaluating the performance of artificial neural networks for the classification of freshwater benthic macroinvertebrates

(2014) Henry Joutsijoki et al.   Ecological Informatics

Ca2+ signaling in human induced pluripotent stem cell-derived cardiomyocytes (iPS-CM) from normal and catecholaminergic polymorphic ventricular tachycardia (CPVT)-afflicted subjects

(2013) X.-H. Zhang et al.   CELL CALCIUM

Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells

(2013) Feng Lan et al.   Cell Stem Cell

Structural and Functional Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells

(2013) Scott D. Lundy et al.   STEM CELLS AND DEVELOPMENT

CaMKII inhibition rectifies arrhythmic phenotype in a patient-specific model of catecholaminergic polymorphic ventricular tachycardia

(2013) E Di Pasquale et al.   Cell Death & Disease

Optical Imaging of Voltage and Calcium in Cardiac Cells & Tissues

(2012) Todd J. Herron et al.   CIRCULATION RESEARCH

Modeling of Catecholaminergic Polymorphic Ventricular Tachycardia With Patient-Specific Human-Induced Pluripotent Stem Cells

(2012) Ilanit Itzhaki et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cell Model of Catecholaminergic Polymorphic Ventricular Tachycardia Reveals Early and Delayed Afterdepolarizations

(2012) Kirsi Kujala et al.   PLoS One

In vitro Modeling of Ryanodine Receptor 2 Dysfunction Using Human Induced Pluripotent Stem Cells

(2011) Azra Fatima et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture

(2011) A. L. Lahti et al.   Disease Models & Mechanisms

Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia

(2011) Christian B. Jung et al.   EMBO Molecular Medicine

Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation

(2011) Elena Matsa et al.   EUROPEAN HEART JOURNAL

Cardiomyocytes derived from human embryonic and induced pluripotent stem cells: comparative ultrastructure

(2011) Mihaela Gherghiceanu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Calcium Handling in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes

(2011) Ilanit Itzhaki et al.   PLoS One

Calcium Homeostasis in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

(2011) Yee-Ki Lee et al.   Stem Cell Reviews and Reports

Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome

(2010) Alessandra Moretti et al.   NEW ENGLAND JOURNAL OF MEDICINE