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Identification of lipases with activity towards monoacylglycerol by criterion of conserved cap architectures

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Cyclipostins and cyclophostin analogs inhibit the antigen 85C fromMycobacterium tuberculosisbothin vitroandin vivo

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Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling

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Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p

(2016) Philipp Aschauer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

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(2016) Laura Scalvini et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Chewing the fat: lipid metabolism and homeostasis during M. tuberculosis infection

(2016) Rustin R Lovewell et al.   CURRENT OPINION IN MICROBIOLOGY

Experimental Models of Foamy Macrophages and Approaches for Dissecting the Mechanisms of Lipid Accumulation and Consumption during Dormancy and Reactivation of Tuberculosis

(2016) Pierre Santucci et al.   Frontiers in Cellular and Infection Microbiology

Small-Molecule Probes Reveal Esterases with Persistent Activity in Dormant and Reactivating Mycobacterium tuberculosis

(2016) Katie R. Tallman et al.   ACS Infectious Diseases

OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins

(2015) Edward Harder et al.   Journal of Chemical Theory and Computation

Purification, crystallization and preliminary X-ray diffraction analysis of a soluble variant of the monoglyceride lipase Yju3p from the yeastSaccharomyces cerevisiae

(2015) Srinivasan Rengachari et al.   Acta Crystallographica Section F-Structural Biology Communications

Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents

(2015) Guy Griebel et al.   Scientific Reports

Mycolic Acids: Structures, Biosynthesis, and Beyond

(2014) Hedia Marrakchi et al.   CHEMISTRY & BIOLOGY

Exploitation of host lipids by bacteria

(2013) François Vromman et al.   CURRENT OPINION IN MICROBIOLOGY

Conformational Plasticity and Ligand Binding of Bacterial Monoacylglycerol Lipase

(2013) Srinivasan Rengachari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes

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Mycobacterial lipolytic enzymes: A gold mine for tuberculosis research

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LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

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(2011) Paul D. Adams et al.   METHODS

Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Å resolution

(2011) Céline Schalk-Hihi et al.   PROTEIN SCIENCE

Mycobacterium tuberculosis Uses Host Triacylglycerol to Accumulate Lipid Droplets and Acquires a Dormancy-Like Phenotype in Lipid-Loaded Macrophages

(2011) Jaiyanth Daniel et al.   PLoS Pathogens

A Monoacylglycerol Lipase from Mycobacterium smegmatis Involved in Bacterial Cell Interaction

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MolProbity: all-atom structure validation for macromolecular crystallography

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Crystal Structure of the Human Monoacylglycerol Lipase, a Key Actor in Endocannabinoid Signaling

(2009) Geoffray Labar et al.   CHEMBIOCHEM

Triacylglycerol Utilization Is Required for Regrowth of In Vitro Hypoxic Nonreplicating Mycobacterium bovis Bacillus Calmette-Guerin

(2009) K. L. Low et al.   JOURNAL OF BACTERIOLOGY

Structural Basis for Human Monoglyceride Lipase Inhibition

(2009) T. Bertrand et al.   JOURNAL OF MOLECULAR BIOLOGY

Lipids in host–pathogen interactions: Pathogens exploit the complexity of the host cell lipidome

(2009) Ynske P.M. van der Meer-Janssen et al.   PROGRESS IN LIPID RESEARCH

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

(2008) Jonathan Z Long et al.   Nature Chemical Biology

PROMALS3D: a tool for multiple protein sequence and structure alignments

(2008) Jimin Pei et al.   NUCLEIC ACIDS RESEARCH

Foamy Macrophages from Tuberculous Patients' Granulomas Constitute a Nutrient-Rich Reservoir for M. tuberculosis Persistence

(2008) Pascale Peyron et al.   PLoS Pathogens