Impact of the griffithsin anti-HIV microbicide and placebo gels on the rectal mucosal proteome and microbiome in non-human primates

Correlates of condomless anal sex among men who have sex with men (MSM) in Tijuana, Mexico: The role of public sex venues

(2017) Shirley J. Semple et al.   PLoS One

Rectal 1% Tenofovir Gel Use Associates with Altered Epidermal Protein Expression

(2016) Laura Romas et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

The rectal mucosa and condomless receptive anal intercourse in HIV-negative MSM: implications for HIV transmission and prevention

(2016) C F Kelley et al.   Mucosal Immunology

DADA2: High-resolution sample inference from Illumina amplicon data

(2016) Benjamin J Callahan et al.   NATURE METHODS

Studies in a Murine Model Confirm the Safety of Griffithsin and Advocate Its Further Development as a Microbicide Targeting HIV-1 and Other Enveloped Viruses

(2016) Joseph Kouokam et al.   Viruses-Basel

Anti-nociceptive effect of Faecalibacterium prausnitzii in non-inflammatory IBS-like models

(2016) S. Miquel et al.   Scientific Reports

Microbiome Composition and Function Drives Wound-Healing Impairment in the Female Genital Tract

(2016) Alexander S. Zevin et al.   PLoS Pathogens

Gut Microbiota Linked to Sexual Preference and HIV Infection

(2016) Marc Noguera-Julian et al.   EBioMedicine

Genital Inflammation and the Risk of HIV Acquisition in Women

(2015) Lindi Masson et al.   CLINICAL INFECTIOUS DISEASES

Molecular Signatures of Immune Activation and Epithelial Barrier Remodeling Are Enhanced during the Luteal Phase of the Menstrual Cycle: Implications for HIV Susceptibility

(2015) Kenzie Birse et al.   JOURNAL OF VIROLOGY

Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins and an influx of HIV-susceptible target cells

(2015) Kelly B Arnold et al.   Mucosal Immunology

Rectal Application of a Highly Osmolar Personal Lubricant in a Macaque Model Induces Acute Cytotoxicity but Does Not Increase Risk of SHIV Infection

(2015) Sundaram A. Vishwanathan et al.   PLoS One

Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study

(2015) Karen Smith-McCune et al.   PLoS One

Factors Associated with Inconsistent Condom Use among Men Who Have Sex with Men in Cambodia

(2015) Siyan Yi et al.   PLoS One

Estimating per-act HIV transmission risk

(2014) Pragna Patel et al.   AIDS

A Comparative Proteomic Analysis of the Soluble Immune Factor Environment of Rectal and Oral Mucosa

(2014) Laura M. Romas et al.   PLoS One

An improved dual-indexing approach for multiplexed 16S rRNA gene sequencing on the Illumina MiSeq platform

(2014) Douglas W Fadrosh et al.   Microbiome

The increase in global HIV epidemics in MSM

(2013) Chris Beyrer et al.   AIDS

Vaginally Delivered Tenofovir Disoproxil Fumarate Provides Greater Protection than Tenofovir against Genital Herpes in a Murine Model of Efficacy and Safety

(2013) Briana Nixon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Rectal pre-exposure prophylaxis (PrEP)

(2013) Lisa C. Rohan et al.   ANTIVIRAL RESEARCH

The development of rectal microbicides for HIV prevention

(2013) Ian McGowan   Expert Opinion on Drug Delivery

Griffithsin Protects Mice from Genital Herpes by Preventing Cell-to-Cell Spread

(2013) B. Nixon et al.   JOURNAL OF VIROLOGY

Male Sex Workers Who Sell Sex to Men Also Engage in Anal Intercourse with Women: Evidence from Mombasa, Kenya

(2013) Priya Mannava et al.   PLoS One

A Phase 1 Randomized, Double Blind, Placebo Controlled Rectal Safety and Acceptability Study of Tenofovir 1% Gel (MTN-007)

(2013) Ian Mcgowan et al.   PLoS One

RMP-02/MTN-006: A Phase 1 Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Tenofovir 1% Gel Compared with Oral Tenofovir Disoproxil Fumarate

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Global epidemiology of HIV infection in men who have sex with men

(2012) Chris Beyrer et al.   LANCET

Worldwide burden of HIV in transgender women: a systematic review and meta-analysis

(2012) Stefan D Baral et al.   LANCET INFECTIOUS DISEASES

The SILVA ribosomal RNA gene database project: improved data processing and web-based tools

(2012) Christian Quast et al.   NUCLEIC ACIDS RESEARCH

HIV Prevention in High-Risk Women in South Africa: Condom Use and the Need for Change

(2012) Francois van Loggerenberg et al.   PLoS One

Twice-Daily Application of HIV Microbicides Alter the Vaginal Microbio

(2012) J. Ravel et al.   mBio

Bacterial Vaginosis Associated with Increased Risk of Female-to-Male HIV-1 Transmission: A Prospective Cohort Analysis among African Couples

(2012) Craig R. Cohen et al.   PLOS MEDICINE

Identification of Personal Lubricants That Can Cause Rectal Epithelial Cell Damage and Enhance HIV Type 1 Replication in Vitro

(2011) Othell Begay et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

First Phase 1 Double-Blind, Placebo-Controlled, Randomized Rectal Microbicide Trial Using UC781 Gel with a Novel Index of Ex Vivo Efficacy

(2011) Peter A. Anton et al.   PLoS One

Investigation of Griffithsin's Interactions with Human Cells Confirms Its Outstanding Safety and Efficacy Profile as a Microbicide Candidate

(2011) Joseph Calvin Kouokam et al.   PLoS One

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

(2009) B. R. O'Keefe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

A Randomized Six-Day Safety Study of an Antiretroviral Microbicide Candidate UC781, a Non-Nucleoside Reverse Transcriptase Inhibitor

(2008) Jill L. Schwartz et al.   SEXUALLY TRANSMITTED DISEASES