Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells

Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency

(2016) Victoria Capel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Enhancing Endosomal Escape for Intracellular Delivery of Macromolecular Biologic Therapeutics

(2016) Peter Lönn et al.   Scientific Reports

The effect of the size of fluorescent dextran on its endocytic pathway

(2015) Lei Li et al.   CELL BIOLOGY INTERNATIONAL

Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown

(2015) Anders Wittrup et al.   NATURE BIOTECHNOLOGY

Different endocytotic uptake mechanisms for nanoparticles in epithelial cells and macrophages

(2014) Dagmar A Kuhn et al.   Beilstein Journal of Nanotechnology

Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

(2013) Jerome Gilleron et al.   NATURE BIOTECHNOLOGY

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

(2013) Gaurav Sahay et al.   NATURE BIOTECHNOLOGY

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

Deciphering the mechanisms of cellular uptake of engineered nanoparticles by accurate evaluation of internalization using imaging flow cytometry

(2013) Sandra Vranic et al.   Particle and Fibre Toxicology

A Novel Liposome-Based Nanocarrier Loaded with an LPS-dsRNA Cocktail for Fish Innate Immune System Stimulation

(2013) Angels Ruyra et al.   PLoS One

The endocytosis and intracellular fate of nanomedicines: Implication for rational design

(2013) Longfa Kou et al.   Asian Journal of Pharmaceutical Sciences

The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

(2012) Eleonore Fröhlich   International Journal of Nanomedicine

Action and Reaction: The Biological Response to siRNA and Its Delivery Vehicles

(2012) Rosemary L Kanasty et al.   MOLECULAR THERAPY

Comparative cellular pharmacokinetics and pharmacodynamics of siRNA delivery by SPANosomes and by cationic liposomes

(2012) Chenguang Zhou et al.   Nanomedicine-Nanotechnology Biology and Medicine

Functional lipids and lipoplexes for improved gene delivery

(2011) Xiao-Xiang Zhang et al.   BIOCHIMIE

Cholesterol sequestration by nystatin enhances the uptake and activity of endostatin in endothelium via regulating distinct endocytic pathways

(2011) Y. Chen et al.   BLOOD

Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies

(2011) Tore-Geir Iversen et al.   Nano Today

Effects of Transport Inhibitors on the Cellular Uptake of Carboxylated Polystyrene Nanoparticles in Different Cell Lines

(2011) Tiago dos Santos et al.   PLoS One

Breaking down the barriers: siRNA delivery and endosome escape

(2010) M. Dominska et al.   JOURNAL OF CELL SCIENCE

Endocytosis of nanomedicines

(2010) Gaurav Sahay et al.   JOURNAL OF CONTROLLED RELEASE

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(2010) Jennifer Ziello et al.   MOLECULAR MEDICINE

siRNA delivery systems for cancer treatment

(2009) Yu-Kyoung Oh et al.   ADVANCED DRUG DELIVERY REVIEWS

Inhibitors of clathrin-dependent endocytosis enhance TGF  signaling and responses

(2009) C.-L. Chen et al.   JOURNAL OF CELL SCIENCE

Endocytosisviacaveolae: alternative pathway with distinct cellular compartments to avoid lysosomal degradation?

(2009) Anna L. Kiss et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lipid-based nanotherapeutics for siRNA delivery

(2009) A. Schroeder et al.   JOURNAL OF INTERNAL MEDICINE

A Novel Mechanism Is Involved in Cationic Lipid-Mediated Functional siRNA Delivery

(2009) James J. Lu et al.   MOLECULAR PHARMACEUTICS

The Use of Inhibitors to Study Endocytic Pathways of Gene Carriers: Optimization and Pitfalls

(2009) Dries Vercauteren et al.   MOLECULAR THERAPY

Surface Charge of Nanoparticles Determines Their Endocytic and Transcytotic Pathway in Polarized MDCK Cells

(2008) Oshrat Harush-Frenkel et al.   BIOMACROMOLECULES

The effect of surface functionality on cellular trafficking of dendrimers

(2008) Omathanu P. Perumal et al.   BIOMATERIALS

Endocytosis Inhibitors Prevent Poly(amidoamine) Dendrimer Internalization and Permeability across Caco-2 Cells

(2008) Kelly M. Kitchens et al.   MOLECULAR PHARMACEUTICS

Cellular attachment and internalization of cationic liposomes containing mycobacterial cell wall

(2008) Atthachai Homhuan et al.   SCIENCEASIA