Autoantibodies against the Immunoglobulin-Binding Region of Ro52 Link its Autoantigenicity with Pathogen Neutralization

Cocapture of cognate and bystander antigens can activate autoreactive B cells

(2017) Nicholas S. R. Sanderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordinated Neutralization and Immune Activation by the Cytosolic Antibody Receptor TRIM21

(2016) Adam J. Fletcher et al.   JOURNAL OF VIROLOGY

TRIM21 Ubiquitylates SQSTM1/p62 and Suppresses Protein Sequestration to Regulate Redox Homeostasis

(2016) Ji-An Pan et al.   MOLECULAR CELL

Transcriptomic Segregation of Human Autoantigens Useful for the Diagnosis of Autoimmune Diseases

(2016) Peter D. Burbelo et al.   Molecular Diagnosis & Therapy

Brief Report: Patients With Primary Sjögren's Syndrome Who Are Positive for Autoantibodies to Tripartite Motif-Containing Protein 38 Show Greater Disease Severity

(2016) Nina Wolska et al.   Arthritis & Rheumatology

TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity

(2015) Stian Foss et al.   IMMUNOLOGICAL REVIEWS

Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21

(2015) Adam J. Fletcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Luciferase immunoprecipitation systems for measuring antibodies in autoimmune and infectious diseases

(2015) Peter D. Burbelo et al.   Translational Research

Trim21 regulates Nmi-IFI35 complex-mediated inhibition of innate antiviral response

(2015) Anshuman Das et al.   VIROLOGY

Serological epitope profile of anti-Ro52–positive patients with systemic autoimmune rheumatic diseases

(2015) Maria Infantino et al.   ARTHRITIS RESEARCH & THERAPY

TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus

(2015) Ruth E. Watkinson et al.   PLoS Pathogens

Prediction of Sjögren's Syndrome Years Before Diagnosis and Identification of Patients With Early Onset and Severe Disease Course by Autoantibody Profiling

(2015) Elke Theander et al.   Arthritis & Rheumatology

The E3 Ubiquitin Ligase Ro52 Negatively Regulates IFN-  Production Post-Pathogen Recognition by Polyubiquitin-Mediated Degradation of IRF3

(2014) R. Higgs et al.   JOURNAL OF IMMUNOLOGY

Nucleotide Biosynthetic Enzyme GMP Synthase Is a TRIM21-Controlled Relay of p53 Stabilization

(2014) B. Ashok Reddy et al.   MOLECULAR CELL

Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies

(2014) Caitlin Gillis et al.   Frontiers in Immunology

Simultaneous Neutralization and Innate Immune Detection of a Replicating Virus by TRIM21

(2013) R. E. Watkinson et al.   JOURNAL OF VIROLOGY

A genome-wide association study in Han Chinese identifies a susceptibility locus for primary Sjögren's syndrome at 7q11.23

(2013) Yongzhe Li et al.   NATURE GENETICS

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

(2013) Christopher J Lessard et al.   NATURE GENETICS

Intracellular antibody receptor TRIM21 prevents fatal viral infection

(2013) M. Vaysburd et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical and Pathological Roles of Ro/SSA Autoantibody System

(2012) Ryusuke Yoshimi et al.   Clinical & Developmental Immunology

The immunobiology of Ro52 (TRIM21) in autoimmunity: A critical review

(2012) Vilija Oke et al.   JOURNAL OF AUTOIMMUNITY

Two Major Autoantibody Clusters in Systemic Lupus Erythematosus

(2012) Kathryn H. Ching et al.   PLoS One

AAA ATPase p97/VCP is essential for TRIM21-mediated virus neutralization

(2012) F. Hauler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-Ro and anti-La autoantibody profiling in Norwegian patients with primary Sjögren’s syndrome using luciferase immunoprecipitation systems (LIPS)

(2012) R Volchenkov et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

American College of Rheumatology classification criteria for Sjögren's syndrome: A data-driven, expert consensus approach in the Sjögren's International Collaborative Clinical Alliance Cohort

(2012) S. C. Shiboski et al.   ARTHRITIS CARE & RESEARCH

Salivary anti-Ro60 and anti-Ro52 Antibody Profiles to Diagnose Sjögren’s Syndrome

(2011) K.H. Ching et al.   JOURNAL OF DENTAL RESEARCH

Sera from patients with rheumatic diseases recognize different epitope regions on the 52-kD Ro/SS-A protein

(2010) B. BOŽIČ et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Fc Receptor-Like A Associates with Intracellular IgG and IgM but Is Dispensable for Antigen-Specific Immune Responses

(2010) T. J. Wilson et al.   JOURNAL OF IMMUNOLOGY

Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)

(2010) D. L. Mallery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensitive and robust luminescent profiling of anti-La and other autoantibodies in Sjögren's syndrome

(2009) Peter D. Burbelo et al.   AUTOIMMUNITY

Ro52-mediated Monoubiquitination of IKK  Down-regulates NF- B Signalling

(2009) K. Wada et al.   JOURNAL OF BIOCHEMISTRY

Antibody Profiling by Luciferase Immunoprecipitation Systems (LIPS)

(2009) Peter D. Burbelo et al.   Jove-Journal of Visualized Experiments