In vitro patient-derived 3D mesothelioma tumor organoids facilitate patient-centric therapeutic screening

Diagnostic utility of BAP1 and EZH2 expression in malignant mesothelioma

(2017) Aya Shinozaki-Ushiku et al.   HISTOPATHOLOGY

A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening

(2016) Aleksander Skardal et al.   BIOTECHNOLOGY AND BIOENGINEERING

A tunable hydrogel system for long-term release of cell-secreted cytokines and bioprinted in situ wound cell delivery

(2016) Aleksander Skardal et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Bioprinting Cellularized Constructs Using a Tissue-specific Hydrogel Bioink

(2016) Aleksander Skardal et al.   Jove-Journal of Visualized Experiments

A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs

(2015) Aleksander Skardal et al.   Acta Biomaterialia

Engineered In Vitro Disease Models

(2015) Kambez H. Benam et al.   Annual Review of Pathology-Mechanisms of Disease

Translating genomic discoveries to the clinic in pediatric oncology

(2015) Julia Glade Bender et al.   CURRENT OPINION IN PEDIATRICS

Recent innovations in the USA National Cancer Institute-sponsored investigator initiated Phase I and II anticancer drug development: Figure 1.

(2015) Hideaki Bando et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Prospective Clinical Study of Precision Oncology in Solid Tumors

(2015) Davendra P. S. Sohal et al.   JNCI-Journal of the National Cancer Institute

Loss of BAP1 function leads to EZH2-dependent transformation

(2015) Lindsay M LaFave et al.   NATURE MEDICINE

Genetic Testing and Tissue Banking for Personalized Oncology: Analytical and Institutional Factors

(2015) George Miles et al.   SEMINARS IN ONCOLOGY

Organoid modeling for cancer precision medicine

(2015) Michael A Cantrell et al.   Genome Medicine

Prospective Clinical Study of Precision Oncology in Solid Tumors

(2015) Davendra P. S. Sohal et al.   JNCI-Journal of the National Cancer Institute

Precision medicine in colorectal cancer: the molecular profile alters treatment strategies

(2015) Nguyen H. Tran et al.   Therapeutic Advances in Medical Oncology

DZNep inhibits the proliferation of colon cancer HCT116 cells by inducing senescence and apoptosis

(2015) Mingquan Sha et al.   Acta Pharmaceutica Sinica B

Prioritizing targets for precision cancer medicine

(2014) F. Andre et al.   ANNALS OF ONCOLOGY

Translating Genomics for Precision Cancer Medicine

(2014) Roychowdhury Sameek et al.   Annual Review of Genomics and Human Genetics

Organoid Cultures Derived from Patients with Advanced Prostate Cancer

(2014) Dong Gao et al.   CELL

Organs-on-a-chip: a new tool for drug discovery

(2014) Alessandro Polini et al.   Expert Opinion on Drug Discovery

Pneumatic valves in folded 2D and 3D fluidic devices made from plastic films and tapes

(2014) Gregory A. Cooksey et al.   LAB ON A CHIP

The Spectrum of SWI/SNF Mutations, Ubiquitous in Human Cancers

(2013) A. Hunter Shain et al.   PLoS One

Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function

(2012) Aleksander Skardal et al.   BIOMATERIALS

Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues

(2011) Maren Drewitz et al.   Biotechnology Journal

Biomimetic tissues on a chip for drug discovery

(2011) Amir M. Ghaemmaghami et al.   DRUG DISCOVERY TODAY

Toxicity Testing in the 21st Century: Defining New Risk Assessment Approaches Based on Perturbation of Intracellular Toxicity Pathways

(2011) Sudin Bhattacharya et al.   PLoS One

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

The generation of 3-D tissue models based on hyaluronan hydrogel-coated microcarriers within a rotating wall vessel bioreactor

(2010) Aleksander Skardal et al.   BIOMATERIALS

Incorporation of multicellular spheroids into 3-D polymeric scaffolds provides an improved tumor model for screening anticancer drugs

(2010) Won Jin Ho et al.   CANCER SCIENCE

A Useful Antibody Panel for Differential Diagnosis Between Peritoneal Mesothelioma and Ovarian Serous Carcinoma in Japanese Cases

(2008) Yukio Takeshima et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Modular extracellular matrices: Solutions for the puzzle

(2008) Monica A. Serban et al.   METHODS

Evaluating Drug Efficacy and Toxicology in Three Dimensions: Using Synthetic Extracellular Matrices in Drug Discovery

(2007) Glenn D. Prestwich   ACCOUNTS OF CHEMICAL RESEARCH