Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice
Authors
Keywords
-
Journal
Scientific Reports
Volume 8, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-01-03
DOI
10.1038/s41598-017-18388-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Neuronal human BACE1 knockin induces systemic diabetes in mice
- (2016) Kaja Plucińska et al. DIABETOLOGIA
- Inflammatory cause of metabolic syndrome via brain stress and NF-κB
- (2016) Dongsheng Cai et al. Aging-US
- Diet-Induced Obese Mice Retain Endogenous Leptin Action
- (2015) Nickki Ottaway et al. Cell Metabolism
- Alzheimer-associated A oligomers impact the central nervous system to induce peripheral metabolic deregulation
- (2015) J. R. Clarke et al. EMBO Molecular Medicine
- Leptin Mediates the Increase in Blood Pressure Associated with Obesity
- (2014) Stephanie E. Simonds et al. CELL
- Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes
- (2014) D. Lee Hamilton et al. DIABETOLOGIA
- Leptin receptor neurons in the dorsomedial hypothalamus are key regulators of energy expenditure and body weight, but not food intake
- (2014) Kavon Rezai-Zadeh et al. Molecular Metabolism
- Hypothalamic Inflammation: Marker or Mechanism of Obesity Pathogenesis?
- (2013) Joshua P. Thaler et al. DIABETES
- AZ-4217: A High Potency BACE Inhibitor Displaying Acute Central Efficacy in Different In Vivo Models and Reduced Amyloid Deposition in Tg2576 Mice
- (2013) S. Eketjall et al. JOURNAL OF NEUROSCIENCE
- Leptin signaling and leptin resistance
- (2013) Yingjiang Zhou et al. Frontiers of Medicine
- Amyloid- Induces Hepatic Insulin Resistance by Activating JAK2/STAT3/SOCS-1 Signaling Pathway
- (2012) Y. Zhang et al. DIABETES
- BACE1 is at the crossroad of a toxic vicious cycle involving cellular stress and β-amyloid production in Alzheimer’s disease
- (2012) Linda Chami et al. Molecular Neurodegeneration
- Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice
- (2011) Paul J. Meakin et al. BIOCHEMICAL JOURNAL
- Obesity is associated with hypothalamic injury in rodents and humans
- (2011) Joshua P. Thaler et al. JOURNAL OF CLINICAL INVESTIGATION
- Diet-Induced Obesity Attenuates Fasting-Induced Hyperphagia
- (2011) D. I. Briggs et al. JOURNAL OF NEUROENDOCRINOLOGY
- Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons
- (2011) Linh Vong et al. NEURON
- The Melanocortin-4 Receptor: Physiology, Pharmacology, and Pathophysiology
- (2010) Ya-Xiong Tao ENDOCRINE REVIEWS
- Obesity and leptin resistance: distinguishing cause from effect
- (2010) Martin G. Myers et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance
- (2009) Lale Ozcan et al. Cell Metabolism
- Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease
- (2008) Wei-Qin Zhao et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity
- (2008) Xiaoqing Zhang et al. CELL
- Understanding BACE1: essential protease for amyloid-β production in Alzheimer’s disease
- (2008) J. H. Stockley et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Endoplasmic Reticulum Stress Induces Leptin Resistance
- (2008) T. Hosoi et al. MOLECULAR PHARMACOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started