DNA-release by Streptococcus pneumoniae autolysin LytA induced Krueppel-like factor 4 expression in macrophages

Role of Pneumococcal Autolysin for KLF4 Expression and Chemokine Secretion in Lung Epithelium

(2015) Janine Zahlten et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Serotype 1 and 8 Pneumococci Evade Sensing by Inflammasomes in Human Lung Tissue

(2015) Diana Fatykhova et al.   PLoS One

Kruppel-Like Factor 4 Is Essential for Inflammatory Monocyte Differentiation In Vivo

(2014) J. K. Alder et al.   JOURNAL OF IMMUNOLOGY

Community-Acquired Pneumonia

(2014) Daniel M. Musher et al.   NEW ENGLAND JOURNAL OF MEDICINE

Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

(2013) D. Kurotaki et al.   BLOOD

A Defined Methodology for Reliable Quantification of Western Blot Data

(2013) Sean C. Taylor et al.   MOLECULAR BIOTECHNOLOGY

Innate immune detection of microbial nucleic acids

(2013) Claudia Gürtler et al.   TRENDS IN MICROBIOLOGY

High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9–TRIF pathway

(2013) Claudia Volpi et al.   Nature Communications

Pneumococcal Pneumonia

(2012) David H. Dockrell et al.   CHEST

TLR9- and Src-dependent expression of Krueppel-like factor 4 controls interleukin-10 expression in pneumonia

(2012) Janine Zahlten et al.   EUROPEAN RESPIRATORY JOURNAL

FMS-Like Tyrosine Kinase 3 Ligand Treatment of Mice Aggravates Acute Lung Injury in Response to Streptococcus pneumoniae: Role of Pneumolysin

(2012) Christina Brumshagen et al.   INFECTION AND IMMUNITY

Supporting conditional mouse mutagenesis with a comprehensive cre characterization resource

(2012) Caleb S. Heffner et al.   Nature Communications

Recognition of Streptococcus pneumoniae by the innate immune system

(2011) Uwe Koppe et al.   CELLULAR MICROBIOLOGY

Krüppel-like factor 4 regulates macrophage polarization

(2011) Xudong Liao et al.   JOURNAL OF CLINICAL INVESTIGATION

Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice

(2011) Shigeki Nakamura et al.   JOURNAL OF CLINICAL INVESTIGATION

Streptococcus pneumoniae Stimulates a STING- and IFN Regulatory Factor 3-Dependent Type I IFN Production in Macrophages, which Regulates RANTES Production in Macrophages, Cocultured Alveolar Epithelial Cells, and Mouse Lungs

(2011) U. Koppe et al.   JOURNAL OF IMMUNOLOGY

The NLRP3 Inflammasome Is Differentially Activated by Pneumolysin Variants and Contributes to Host Defense in Pneumococcal Pneumonia

(2011) M. Witzenrath et al.   JOURNAL OF IMMUNOLOGY

Innate Immune Sensing of DNA

(2011) Shruti Sharma et al.   PLoS Pathogens

Identification and functions of pattern-recognition receptors

(2010) Yutaro Kumagai et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TLR2- and Nucleotide-Binding Oligomerization Domain 2-Dependent Kruppel-Like Factor 2 Expression Downregulates NF- B-Related Gene Expression

(2010) J. Zahlten et al.   JOURNAL OF IMMUNOLOGY

Krüppel-like factor 4, a novel transcription factor regulates microglial activation and subsequent neuroinflammation

(2010) Deepak K Kaushik et al.   Journal of Neuroinflammation

Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cells

(2009) Guadalupe Villarreal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

(2009) Arash Shahangian et al.   JOURNAL OF CLINICAL INVESTIGATION

Pattern recognition receptors and control of adaptive immunity

(2008) Noah W. Palm et al.   IMMUNOLOGICAL REVIEWS

Pneumolysin Released during Streptococcus pneumoniae Autolysis Is a Potent Activator of Intracellular Oxygen Radical Production in Neutrophils

(2008) A. Martner et al.   INFECTION AND IMMUNITY

The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease

(2008) Aras Kadioglu et al.   NATURE REVIEWS MICROBIOLOGY